RU2015109591A - Молекулы с антигенсвязывающей активностью и способностью к поливалентному связыванию с fc-гамма-рецепторами - Google Patents

Молекулы с антигенсвязывающей активностью и способностью к поливалентному связыванию с fc-гамма-рецепторами Download PDF

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RU2015109591A
RU2015109591A RU2015109591A RU2015109591A RU2015109591A RU 2015109591 A RU2015109591 A RU 2015109591A RU 2015109591 A RU2015109591 A RU 2015109591A RU 2015109591 A RU2015109591 A RU 2015109591A RU 2015109591 A RU2015109591 A RU 2015109591A
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Хенрик ОЛСЕН
Дэвид БЛОК
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Гликник Инк.
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components
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    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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RU2015109591A 2012-08-20 2013-08-20 Молекулы с антигенсвязывающей активностью и способностью к поливалентному связыванию с fc-гамма-рецепторами RU2015109591A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261691057P 2012-08-20 2012-08-20
US61/691,057 2012-08-20
US201361785144P 2013-03-14 2013-03-14
US61/785,144 2013-03-14
PCT/US2013/055800 WO2014031646A2 (en) 2012-08-20 2013-08-20 Molecules with antigen binding and polyvalent fc gamma receptor binding activity

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RU2015109591A true RU2015109591A (ru) 2016-10-20

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US (2) US9683044B2 (enExample)
EP (1) EP2885320A4 (enExample)
JP (1) JP2015527366A (enExample)
KR (1) KR20150058236A (enExample)
CN (1) CN104718223A (enExample)
AU (1) AU2013305885B2 (enExample)
BR (1) BR112015003459A2 (enExample)
CA (1) CA2882296A1 (enExample)
HK (1) HK1210792A1 (enExample)
IL (1) IL237307A0 (enExample)
MX (1) MX2015002269A (enExample)
RU (1) RU2015109591A (enExample)
WO (1) WO2014031646A2 (enExample)

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CA2882296A1 (en) 2014-02-27
US9683044B2 (en) 2017-06-20
BR112015003459A2 (pt) 2017-09-26
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AU2013305885A1 (en) 2015-03-05
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HK1210792A1 (en) 2016-05-06
US20180094061A1 (en) 2018-04-05
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