RU2011117988A - Система для доставки саморасширяющегося стента - Google Patents
Система для доставки саморасширяющегося стента Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/962—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
- A61F2/966—Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2002/9534—Instruments specially adapted for placement or removal of stents or stent-grafts for repositioning of stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
Abstract
1. Система для доставки саморасширяющегося стента, включающая внутреннюю часть, расположенную коаксиально по отношению к наружной части, причем указанные внутренняя и наружная части включают дистальный и проксимальный конец; толкатель, расположенный на проксимальном конце внутренней части; и скользящий элемент, расположенный коаксиально по отношению к внутренней части, и скользящий элемент расположен в и контактирует с внутренним диаметром стента; причем, до раскрытия стента, стент удерживается во внутреннем диаметре наружной части, и в течение раскрытия стента скользящий элемент может вращаться и двигаться в продольном направлении вдоль внутренней части, позволяя стенту двигаться дистально или вращаться во внутренней части, в то время как наружная часть стягивается для раскрытия стента. ! 2. Система по п.1, отличающаяся тем, что толкатель и внутренняя часть двигаются дистально, в то время как наружная часть стягивается в проксимальном направлении в течение раскрытии стента для аккомодации к укорочению стента. ! 3. Система по п.1, отличающаяся тем, что дополнительно включает дистальный ограничитель, соединенный с внутренней частью в положении, дистальном относительно скользящего элемента. ! 4. Система по п.3, отличающаяся тем, что до того, как наружная часть полностью стягивается для высвобождения стента, внутренняя часть и дистальный ограничитель, соединенный с внутренней частью, двигаются проксимально по отношению к стенту до тех пор, пока дистальный ограничитель не приходит в контакт со скользящим элементом, посредством чего стент удерживается в наружной части. ! 5. Система по п.1, отличающаяся тем, что с
Claims (26)
1. Система для доставки саморасширяющегося стента, включающая внутреннюю часть, расположенную коаксиально по отношению к наружной части, причем указанные внутренняя и наружная части включают дистальный и проксимальный конец; толкатель, расположенный на проксимальном конце внутренней части; и скользящий элемент, расположенный коаксиально по отношению к внутренней части, и скользящий элемент расположен в и контактирует с внутренним диаметром стента; причем, до раскрытия стента, стент удерживается во внутреннем диаметре наружной части, и в течение раскрытия стента скользящий элемент может вращаться и двигаться в продольном направлении вдоль внутренней части, позволяя стенту двигаться дистально или вращаться во внутренней части, в то время как наружная часть стягивается для раскрытия стента.
2. Система по п.1, отличающаяся тем, что толкатель и внутренняя часть двигаются дистально, в то время как наружная часть стягивается в проксимальном направлении в течение раскрытии стента для аккомодации к укорочению стента.
3. Система по п.1, отличающаяся тем, что дополнительно включает дистальный ограничитель, соединенный с внутренней частью в положении, дистальном относительно скользящего элемента.
4. Система по п.3, отличающаяся тем, что до того, как наружная часть полностью стягивается для высвобождения стента, внутренняя часть и дистальный ограничитель, соединенный с внутренней частью, двигаются проксимально по отношению к стенту до тех пор, пока дистальный ограничитель не приходит в контакт со скользящим элементом, посредством чего стент удерживается в наружной части.
5. Система по п.1, отличающаяся тем, что скользящий элемент контактирует с толкателем, в то время как наружная часть стягивается.
6. Система по п.1, отличающаяся тем, что толкатель обеспечивается проксимальным ограничителем.
7. Система по п.1, отличающаяся тем, что наружная часть является наружной оболочкой.
8. Система по п.1, отличающаяся тем, что внутренняя часть является направляющей трубкой-проводником.
9. Система по п.8, отличающаяся тем, что направляющая трубка-проводник является полой.
10. Система по п.1, отличающаяся тем, что внутренняя часть является твердым стержнем.
11. Система по п.1, отличающаяся тем, что скользящий элемент расположен во внутреннем диаметре на внутренней стенке стента.
12. Система по п.1, отличающаяся тем, что скользящий элемент включает наружную часть, образуемую из полимера, и наружная часть скользящего элемента формуется к внутреннему диаметру стента.
13. Система по п.1, отличающаяся тем, что скользящий элемент является ламинированной структурой, имеющей наружную и внутреннюю части, причем наружная часть скользящего элемента образована полимером и формуется к внутреннему диаметру стента, и внутренняя часть скользящего элемента является жесткой частью.
14. Система по п.1, отличающаяся тем, что дополнительно включает смещающий элемент, присоединенный к дистальному концу толкателя, причем смещающий элемент смещает движение стента вдоль оси внутрь системы доставки и толкает проксимальный конец стента в дистальном направлении в течение раскрытия стента.
15. Система по п.1, отличающаяся тем, что саморасширяющийся стент включает полосу несущей спирали, намотанную по спирали вокруг оси стента, причем полоса несущей спирали включает волнообразный структурный компонент несущих элементов, имеющий пики на каждой стороне; множество спиралевидных элементов, намотанных по спирали вокруг оси стента, причем спиралевидные элементы продолжаются в том же направлении, что и полоса несущей спирали, и взаимосвязывают, по крайней мере, некоторые из указанных пиков первого витка через или рядом, по крайней мере, с некоторыми из указанных пиков второго витка полосы несущей спирали, где построенный треугольник геометрической взаимосвязи имеет первую сторону с длиной ножек LC, которая является эффективной длиной спиралевидного элемента между взаимосвязанными пиками первого и второго витков полосы несущей спирали, вторую сторону с длиной ножек, которая является расстоянием по окружности между указанным пиком первого витка и указанным пиком второго витка, взаимосвязанных спиралевидными элементами, разделенным на синус угла As полосы несущей спирали от продольной оси стента, третью сторону с длиной ножек, которая является продольным расстоянием, на которое продолжается полоса несущей спирали в 1 окружности витка (Р1) минус эффективная длина LS несущего элемента, причем первый угол первой стороны равен 180° минус угол As, второй угол второй стороны равен углу Ас спиралевидного элемента от продольной оси, и третий угол третьей стороны равен углу As минус угол Ас, причем соотношение спиралевидный элемент/несущий элемент яляется отношением длины первой ножки LC к длине LS, умноженным на количество прилегающих волнообразных компонентов несущих элементов, образующих полосу несущей спирали, NS, большее или равное приблизительно 1.
16. Система по п.15, отличающаяся тем, что соотношение спиралевидный элемент/несущий элемент больше, чем 2.0.
17. Система по п.15, отличающаяся тем, что полоса несущей спирали включает множество волнообразных компонентов несущих элементов, причем указанные волнообразные компоненты соединены один с другим.
18. Система по п.17, отличающаяся тем, что включает два указанных волнообразных компонента.
19. Система по п.17, отличающаяся тем, что включает три указанных волнообразных компонента.
20. Система по п.15, отличающаяся тем, что дополнительно включает несущую часть, соединенную с концом полосы несущей спирали, причем указанная несущая часть включает множество несущих элементов и намотана вокруг оси стента под острым углом, образованным между плоскостью, перпендикулярной к оси стента, и витком несущей части, причем указанный угол меньше, чем острый угол, образуемый между плоскостью, перпендикулярной к оси стента, и витком полосы несущей спирали; и переходящие части спирали взаимосвязаны между указанной несущей частью и витком полосы несущей спирали, прилегающей к несущей части, и полоса переходящей спирали включает переходящие элементы, связанные, по крайней мере, с некоторыми из спиралевидных элементов витка полосы несущей спирали, прилегающими к указанной несущей части, и, по крайней мере, с некоторыми из несущих элементов несущей части.
21. Система по п.20, отличающаяся тем, что прилегающие элементы переходящей спирали увеличиваются от более короткой длины по окружности стента, в то время как виток несущей части выходит из полосы несущей спирали.
22. Система по п.20, отличающаяся тем, что спиралевидные элементы полосы несущей спирали не соединяются с несущей частью.
23. Система по п.15, отличающаяся тем, что ножки в каждой паре ножек имеют равную длину.
24. Система по п.15, отличающаяся тем, что спиралевидные элементы включают изогнутую переходную часть на каждом конце, причем указанная переходная часть соединена с пиками полосы несущей спирали.
25. Система по п.15, отличающаяся тем, что спиралевидные элементы включают пару спиралевидных частей, разделенных промежутком.
26. Система по п.1, отличающаяся тем, что саморасширяющийся стент включает полосу несущей спирали, намотанную по спирали вокруг оси стента, причем полоса несущей спирали включает волнообразный структурный компонент несущих элементов, и волнообразный структурный компонент имеет пики на каждой стороне; множество спиралевидных элементов, намотанных по спирали вокруг оси стента, причем спиралевидные элементы продолжаются в том же направлении, что и полоса несущей спирали, и взаимосвязывают, по крайней мере, некоторые из указанных пиков первого витка через или рядом, по крайней мере, с некоторыми из указанных пиков второго витка полосы несущей спирали, где построенный треугольник геометрической взаимосвязи имеет первую сторону с длиной ножек LC, которая является эффективной длиной спиралевидного элемента между взаимосвязанными пиками первого и второго витков полосы несущей спирали, вторую сторону с длиной ножек, которая является расстоянием по окружности между указанным пиком первого витка и указанным пиком второго витка, взаимосвязанных спиралевидными элементами, разделенным на синус угла As полосы несущей спирали от продольной оси стента, третью сторону с длиной ножек, которая является продольным расстоянием, на которое продолжается полоса несущей спирали в 1 окружности витка (Р1) минус эффективная длина LS несущего элемента, причем первый угол первой стороны равен 180° минус угол As, второй угол второй стороны равен углу Ас спиралевидного элемента от продольной оси, и третий угол третьей стороны равен углу As минус угол Ас.
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- 2009-10-06 BR BRPI0920690A patent/BRPI0920690B8/pt active IP Right Grant
- 2009-10-06 JP JP2011531104A patent/JP5429828B2/ja active Active
- 2009-10-06 WO PCT/US2009/059604 patent/WO2010042458A1/en active Application Filing
- 2009-10-06 CA CA2739835A patent/CA2739835C/en active Active
- 2009-10-06 KR KR1020117009979A patent/KR101406963B1/ko active IP Right Grant
- 2009-10-06 RU RU2011117988/14A patent/RU2508079C2/ru active
- 2009-10-06 AU AU2009302559A patent/AU2009302559A1/en not_active Abandoned
- 2009-10-06 NZ NZ592332A patent/NZ592332A/en unknown
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JP2012504483A (ja) | 2012-02-23 |
WO2010042458A1 (en) | 2010-04-15 |
US9149376B2 (en) | 2015-10-06 |
CA2739835A1 (en) | 2010-04-15 |
CN102227194B (zh) | 2015-10-07 |
EP2341867A1 (en) | 2011-07-13 |
US10010438B2 (en) | 2018-07-03 |
BRPI0920690B1 (pt) | 2020-07-14 |
BRPI0920690A2 (pt) | 2015-12-29 |
CN102227194A (zh) | 2011-10-26 |
CA2739835C (en) | 2016-11-01 |
NZ592332A (en) | 2012-06-29 |
US20160113794A1 (en) | 2016-04-28 |
KR101406963B1 (ko) | 2014-06-13 |
EP2341867B1 (en) | 2017-12-06 |
AU2009302559A1 (en) | 2010-04-15 |
KR20110084210A (ko) | 2011-07-21 |
US20100094394A1 (en) | 2010-04-15 |
MX2011003665A (es) | 2011-07-04 |
EP2341867A4 (en) | 2014-01-08 |
BRPI0920690B8 (pt) | 2021-06-22 |
JP5429828B2 (ja) | 2014-02-26 |
RU2508079C2 (ru) | 2014-02-27 |
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