RU2004133532A - Фармацевтические препараты с замедленным высвобождением и способы их получения - Google Patents
Фармацевтические препараты с замедленным высвобождением и способы их получения Download PDFInfo
- Publication number
- RU2004133532A RU2004133532A RU2004133532/15A RU2004133532A RU2004133532A RU 2004133532 A RU2004133532 A RU 2004133532A RU 2004133532/15 A RU2004133532/15 A RU 2004133532/15A RU 2004133532 A RU2004133532 A RU 2004133532A RU 2004133532 A RU2004133532 A RU 2004133532A
- Authority
- RU
- Russia
- Prior art keywords
- sustained release
- albuterol
- hour
- release tablet
- composition
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 claims 19
- 239000007939 sustained release tablet Substances 0.000 claims 19
- 238000013268 sustained release Methods 0.000 claims 16
- 239000012730 sustained-release form Substances 0.000 claims 16
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 claims 13
- 229960002052 salbutamol Drugs 0.000 claims 13
- 238000009792 diffusion process Methods 0.000 claims 12
- 229940057282 albuterol sulfate Drugs 0.000 claims 11
- BNPSSFBOAGDEEL-UHFFFAOYSA-N albuterol sulfate Chemical compound OS(O)(=O)=O.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1.CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 BNPSSFBOAGDEEL-UHFFFAOYSA-N 0.000 claims 11
- 239000011248 coating agent Substances 0.000 claims 10
- 238000000576 coating method Methods 0.000 claims 10
- 229920001600 hydrophobic polymer Polymers 0.000 claims 10
- 229920001477 hydrophilic polymer Polymers 0.000 claims 8
- 239000001856 Ethyl cellulose Substances 0.000 claims 6
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims 6
- 235000019325 ethyl cellulose Nutrition 0.000 claims 6
- 229920001249 ethyl cellulose Polymers 0.000 claims 6
- 238000004090 dissolution Methods 0.000 claims 4
- 229920000609 methyl cellulose Polymers 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 239000001761 ethyl methyl cellulose Substances 0.000 claims 3
- 235000010944 ethyl methyl cellulose Nutrition 0.000 claims 3
- 235000020937 fasting conditions Nutrition 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims 2
- 230000003204 osmotic effect Effects 0.000 claims 2
- 239000003826 tablet Substances 0.000 claims 2
- WSVLPVUVIUVCRA-KPKNDVKVSA-N Alpha-lactose monohydrate Chemical compound O.O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O WSVLPVUVIUVCRA-KPKNDVKVSA-N 0.000 claims 1
- 238000013265 extended release Methods 0.000 claims 1
- 229960001021 lactose monohydrate Drugs 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/120,501 US7125563B2 (en) | 2002-04-12 | 2002-04-12 | Sustained release pharmaceutical preparations and methods for producing the same |
| US10/120,501 | 2002-04-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2004133532A true RU2004133532A (ru) | 2005-06-10 |
Family
ID=29214431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004133532/15A RU2004133532A (ru) | 2002-04-12 | 2003-04-11 | Фармацевтические препараты с замедленным высвобождением и способы их получения |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US7125563B2 (enExample) |
| EP (1) | EP1494653A1 (enExample) |
| JP (1) | JP2005532289A (enExample) |
| CN (1) | CN1655765A (enExample) |
| AU (1) | AU2003218397A1 (enExample) |
| CA (1) | CA2481667A1 (enExample) |
| HR (1) | HRP20040945A2 (enExample) |
| PL (1) | PL373328A1 (enExample) |
| RU (1) | RU2004133532A (enExample) |
| WO (1) | WO2003086364A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0203296D0 (en) | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| US8637512B2 (en) | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| ATE341312T1 (de) * | 2003-05-20 | 2006-10-15 | Ethypharm Sa | Orale pharmazeutische zusammensetzung mit verzögerter freisetzung |
| EP2112920B1 (en) | 2003-06-26 | 2018-07-25 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| EP2018160B1 (en) | 2006-03-16 | 2011-12-14 | Tris Pharma, Inc. | Modified release formulations containing drug-ion exchange resin complexes |
| WO2007112581A1 (en) * | 2006-04-03 | 2007-10-11 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| EP2296634A1 (en) * | 2008-06-02 | 2011-03-23 | Dexcel Pharma Technologies Ltd. | Process for manufacture of a medicament with granulation and pan coating |
| WO2011102504A1 (ja) | 2010-02-22 | 2011-08-25 | 第一三共株式会社 | 経口用徐放性固形製剤 |
| EP2540294B1 (en) * | 2010-02-22 | 2016-08-03 | Daiichi Sankyo Company, Limited | Sustained-release solid preparation for oral use |
| US8623409B1 (en) | 2010-10-20 | 2014-01-07 | Tris Pharma Inc. | Clonidine formulation |
| KR102127625B1 (ko) | 2012-09-03 | 2020-06-29 | 다이이찌 산쿄 가부시키가이샤 | 하이드로모르폰염산염 함유의 경구용 서방성 의약 조성물 |
| US11590228B1 (en) | 2015-09-08 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine compositions |
| CR20190142A (es) * | 2016-09-07 | 2019-05-22 | Saniona As | Composiciones de tesofensina |
| US12458592B1 (en) | 2017-09-24 | 2025-11-04 | Tris Pharma, Inc. | Extended release amphetamine tablets |
| US11590081B1 (en) | 2017-09-24 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine tablets |
| US11918689B1 (en) | 2020-07-28 | 2024-03-05 | Tris Pharma Inc | Liquid clonidine extended release composition |
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| US4264573A (en) | 1979-05-21 | 1981-04-28 | Rowell Laboratories, Inc. | Pharmaceutical formulation for slow release via controlled surface erosion |
| US4252786A (en) * | 1979-11-16 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Controlled release tablet |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4503030A (en) | 1983-06-06 | 1985-03-05 | Alza Corporation | Device for delivering drug to certain pH environments |
| US4587117A (en) | 1983-06-06 | 1986-05-06 | Alza Corporation | Medical device for delivering drug to pH environments greater than 3.5 |
| US4851229A (en) | 1983-12-01 | 1989-07-25 | Alza Corporation | Composition comprising a therapeutic agent and a modulating agent |
| US4751071A (en) | 1983-12-01 | 1988-06-14 | Alza Corporation | Composition comprising salbutamol |
| US4777049A (en) | 1983-12-01 | 1988-10-11 | Alza Corporation | Constant release system with pulsed release |
| US4695591A (en) * | 1985-03-29 | 1987-09-22 | Schering Corporation | Controlled release dosage forms comprising hydroxypropylmethylcellulose |
| IT1213080B (it) * | 1986-06-17 | 1989-12-07 | Recordati Chem Pharm | Sistemi terapeutico per la cessione controllata di farmaci. |
| US5254347A (en) | 1988-03-31 | 1993-10-19 | Tanabe Seiyaku Co., Ltd. | Controlled release pharmaceutical preparation and method for producing the same |
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| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
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| SK279684B6 (sk) | 1993-06-14 | 1999-02-11 | Janssen Pharmaceutica N.V. | Tableta a spôsob jej výroby |
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| US5464633A (en) | 1994-05-24 | 1995-11-07 | Jagotec Ag | Pharmaceutical tablets releasing the active substance after a definite period of time |
| SE9402431D0 (sv) | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
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| IL116674A (en) | 1995-01-09 | 2003-05-29 | Mendell Co Inc Edward | Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof |
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| US5674895A (en) | 1995-05-22 | 1997-10-07 | Alza Corporation | Dosage form comprising oxybutynin |
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| SE9600072D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
| US6245351B1 (en) | 1996-03-07 | 2001-06-12 | Takeda Chemical Industries, Ltd. | Controlled-release composition |
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| TW477702B (en) | 1997-10-23 | 2002-03-01 | Dev Center Biotechnology | Controlled release tacrine dosage form |
| US6156347A (en) | 1998-01-21 | 2000-12-05 | Bio-Dar Ltd. | Controlled release chromium picolinate |
| US6251430B1 (en) | 1998-02-04 | 2001-06-26 | Guohua Zhang | Water insoluble polymer based sustained release formulation |
-
2002
- 2002-04-12 US US10/120,501 patent/US7125563B2/en not_active Expired - Fee Related
-
2003
- 2003-04-11 JP JP2003583385A patent/JP2005532289A/ja active Pending
- 2003-04-11 PL PL03373328A patent/PL373328A1/xx not_active Application Discontinuation
- 2003-04-11 RU RU2004133532/15A patent/RU2004133532A/ru not_active Application Discontinuation
- 2003-04-11 HR HR20040945A patent/HRP20040945A2/hr not_active Application Discontinuation
- 2003-04-11 CN CNA038115018A patent/CN1655765A/zh active Pending
- 2003-04-11 CA CA002481667A patent/CA2481667A1/en not_active Abandoned
- 2003-04-11 WO PCT/US2003/009210 patent/WO2003086364A1/en not_active Ceased
- 2003-04-11 AU AU2003218397A patent/AU2003218397A1/en not_active Abandoned
- 2003-04-11 EP EP03714395A patent/EP1494653A1/en not_active Withdrawn
-
2006
- 2006-01-17 US US11/332,158 patent/US20060105037A1/en not_active Abandoned
-
2008
- 2008-01-09 US US11/971,741 patent/US20080107730A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080107730A1 (en) | 2008-05-08 |
| CA2481667A1 (en) | 2003-10-23 |
| AU2003218397A1 (en) | 2003-10-27 |
| US20060105037A1 (en) | 2006-05-18 |
| EP1494653A1 (en) | 2005-01-12 |
| WO2003086364A1 (en) | 2003-10-23 |
| PL373328A1 (en) | 2005-08-22 |
| CN1655765A (zh) | 2005-08-17 |
| JP2005532289A (ja) | 2005-10-27 |
| US20030198670A1 (en) | 2003-10-23 |
| US7125563B2 (en) | 2006-10-24 |
| HRP20040945A2 (en) | 2005-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20070920 |