RU2002105516A - Способ получения тиазоловых производных - Google Patents
Способ получения тиазоловых производных Download PDFInfo
- Publication number
- RU2002105516A RU2002105516A RU2002105516/04A RU2002105516A RU2002105516A RU 2002105516 A RU2002105516 A RU 2002105516A RU 2002105516/04 A RU2002105516/04 A RU 2002105516/04A RU 2002105516 A RU2002105516 A RU 2002105516A RU 2002105516 A RU2002105516 A RU 2002105516A
- Authority
- RU
- Russia
- Prior art keywords
- acid
- chloride
- formula
- source
- anion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/50—Nitrogen atoms bound to hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Claims (11)
1. Соединение, отвечающее формуле
и его кислотно-аддитивные соли.
2. 5-гидрокситиазол-2-диазониевая соль формулы
и ее кислотно-аддитивные соли,
где А- обозначает противоанион, дериватизированный из кислоты НА, где НА обозначает органическую кислоту или неорганическую минеральную кислоту.
3. Способ получения соединения, отвечающего формуле
и его кислотно-аддитивных солей, включающий стадию реакции 2-хлор-5-гидроксиметилтиазола, отвечающего формуле
с источником хлоридного аниона в присутствии кислоты.
4. Способ по п.3, в котором источник хлоридного аниона выбирают из ряда, включающего неорганическую кислоту, хлоридную соль, ацилхлорид и сульфонилхлорид.
5. Способ по п.4, в котором источник хлоридного аниона выбирают из ряда, включающего HCl, SOCl2, PCl3, POCl3, PCl5, ацетилхлорид, бензоилхлорид, мезилхлорид и тозилхлорид.
6. Способ по п.5, в котором источник хлоридного аниона представляет собой тозилхлорид.
7. Способ по п.5, в котором источник хлоридного аниона представляет собой соляную кислоту.
8. Способ получения соединения, отвечающего формуле
и его кислотно-аддитивных солей, включающий стадию реакции 2-гидрокси-5-гидроксиметилтиазола, отвечающего формуле
с источником хлоридного аниона в присутствии кислоты.
9. Способ получения соединения, отвечающего формуле
и его кислотно-аддитивных солей, включающий стадию реакции 5-гидроксиметилтиазолдиазониевой соли формулы
в которой А- обозначает противоанион, дериватизированный из кислоты НА, где НА представляет собой органическую кислоту или неорганическую минеральную кислоту,
с источником хлоридного аниона в присутствии кислоты.
10. Способ получения 5-гидроксиметилтиазолдиазониевой соли формулы
в которой А- обозначает противоанион, дериватизированный из кислоты НА, где НА представляет собой органическую кислоту или неорганическую минеральную кислоту,
включающий стадию реакции соединения, отвечающего формуле
и его кислотно-аддитивных солеи с нитритом щелочного металла в присутствии кислоты.
11. Способ получения соединения, отвечающего формуле
включающий стадию реакции эпоксидного соединения формулы
с тиомочевиной.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/371,180 | 1999-08-10 | ||
| US09/371,180 US6265553B1 (en) | 1999-08-10 | 1999-08-10 | Intermediate thiazoles and process for the preparation of 2-chloro-5-chloromethyl-thiazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2002105516A true RU2002105516A (ru) | 2003-09-20 |
Family
ID=23462834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2002105516/04A RU2002105516A (ru) | 1999-08-10 | 2000-08-08 | Способ получения тиазоловых производных |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US6265553B1 (ru) |
| EP (1) | EP1202979B1 (ru) |
| JP (1) | JP2003506444A (ru) |
| KR (1) | KR20020022796A (ru) |
| CN (2) | CN1169800C (ru) |
| AR (1) | AR030258A1 (ru) |
| AT (1) | ATE294166T1 (ru) |
| AU (1) | AU778367B2 (ru) |
| BR (1) | BR0013235A (ru) |
| CA (1) | CA2380838A1 (ru) |
| CZ (1) | CZ2002483A3 (ru) |
| DE (1) | DE60019763D1 (ru) |
| ES (1) | ES2238029T3 (ru) |
| HU (1) | HUP0202819A3 (ru) |
| MX (1) | MXPA02001246A (ru) |
| RU (1) | RU2002105516A (ru) |
| TR (2) | TR200202474T2 (ru) |
| WO (1) | WO2001010852A1 (ru) |
| ZA (1) | ZA200201110B (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101684079B (zh) | 2003-08-29 | 2013-04-03 | 三井化学株式会社 | 农园艺用杀虫剂的制备中间体及制备方法 |
| US8754053B2 (en) * | 2010-02-17 | 2014-06-17 | Syngenta Crop Protection Llc | Isoxazoline derivatives as insecticides |
| US20120323034A1 (en) * | 2010-02-26 | 2012-12-20 | Sumitomo Chemical Company, Limited | Process for production of cyclopropanecarboxylic acid ester compound |
| AU2012303664A1 (en) * | 2011-09-01 | 2014-04-10 | Biotelliga Holdings Limited | Insecticidal lipid agents isolated from entomopathogenic fungi and uses thereof |
| CN106749086B (zh) * | 2016-12-27 | 2019-05-24 | 江苏振方生物化学有限公司 | 一种农药中间体2-氯-5-氯甲基噻唑的制备方法 |
| CN111036158A (zh) * | 2019-12-28 | 2020-04-21 | 邯郸市瑞田农药有限公司 | 一种2氯-5氯甲基噻唑合成反应系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3631538A1 (de) * | 1986-09-17 | 1988-03-24 | Bayer Ag | Verfahren zur herstellung von 2-chlor-5-chlormethylthiazol |
| US5811555A (en) * | 1995-11-22 | 1998-09-22 | Kureha Chemical Industry Co., Ltd. | Method for substitution of an amino group of a primary amine by a chlorine atom and a synthetic method by application thereof |
| JP2001508452A (ja) * | 1997-01-22 | 2001-06-26 | ノバルティス アクチェンゲゼルシャフト | チアゾール誘導体の製造方法 |
| US5773625A (en) * | 1997-10-02 | 1998-06-30 | Abbott Laboratories | Process for the preparation of disubstituted carbonates |
| US6407251B1 (en) * | 2000-12-28 | 2002-06-18 | Takeda Chemical Industries, Ltd. | Process for preparing 2-chloro-5-chloromethylthiazole |
-
1999
- 1999-08-10 US US09/371,180 patent/US6265553B1/en not_active Expired - Fee Related
-
2000
- 2000-08-08 BR BR0013235-7A patent/BR0013235A/pt not_active IP Right Cessation
- 2000-08-08 AT AT00956412T patent/ATE294166T1/de not_active IP Right Cessation
- 2000-08-08 CN CNB008114455A patent/CN1169800C/zh not_active Expired - Fee Related
- 2000-08-08 TR TR2002/02474T patent/TR200202474T2/xx unknown
- 2000-08-08 CZ CZ2002483A patent/CZ2002483A3/cs unknown
- 2000-08-08 TR TR2002/00304T patent/TR200200304T2/xx unknown
- 2000-08-08 CN CNA2004100566415A patent/CN1626525A/zh active Pending
- 2000-08-08 CA CA002380838A patent/CA2380838A1/en not_active Abandoned
- 2000-08-08 DE DE60019763T patent/DE60019763D1/de not_active Expired - Lifetime
- 2000-08-08 EP EP00956412A patent/EP1202979B1/en not_active Expired - Lifetime
- 2000-08-08 AR ARP000104086A patent/AR030258A1/es not_active Application Discontinuation
- 2000-08-08 AU AU68364/00A patent/AU778367B2/en not_active Ceased
- 2000-08-08 JP JP2001515318A patent/JP2003506444A/ja active Pending
- 2000-08-08 US US10/049,073 patent/US6476230B1/en not_active Expired - Fee Related
- 2000-08-08 ES ES00956412T patent/ES2238029T3/es not_active Expired - Lifetime
- 2000-08-08 WO PCT/EP2000/007709 patent/WO2001010852A1/en active Search and Examination
- 2000-08-08 KR KR1020027001623A patent/KR20020022796A/ko not_active Application Discontinuation
- 2000-08-08 HU HU0202819A patent/HUP0202819A3/hu not_active Application Discontinuation
- 2000-08-08 RU RU2002105516/04A patent/RU2002105516A/ru not_active Application Discontinuation
- 2000-08-08 MX MXPA02001246A patent/MXPA02001246A/es unknown
-
2002
- 2002-02-08 ZA ZA200201110A patent/ZA200201110B/en unknown
- 2002-09-16 US US10/244,236 patent/US6566530B2/en not_active Expired - Fee Related
-
2003
- 2003-05-07 US US10/431,100 patent/US6710182B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AR030258A1 (es) | 2003-08-20 |
| US6566530B2 (en) | 2003-05-20 |
| US6710182B2 (en) | 2004-03-23 |
| US20030191321A1 (en) | 2003-10-09 |
| ES2238029T3 (es) | 2005-08-16 |
| HUP0202819A2 (hu) | 2002-12-28 |
| BR0013235A (pt) | 2002-04-23 |
| CA2380838A1 (en) | 2001-02-15 |
| CN1169800C (zh) | 2004-10-06 |
| AU778367B2 (en) | 2004-12-02 |
| WO2001010852A1 (en) | 2001-02-15 |
| HUP0202819A3 (en) | 2004-03-01 |
| TR200200304T2 (tr) | 2002-06-21 |
| EP1202979B1 (en) | 2005-04-27 |
| DE60019763D1 (de) | 2005-06-02 |
| MXPA02001246A (es) | 2002-07-22 |
| JP2003506444A (ja) | 2003-02-18 |
| US6476230B1 (en) | 2002-11-05 |
| ZA200201110B (en) | 2002-11-27 |
| KR20020022796A (ko) | 2002-03-27 |
| AU6836400A (en) | 2001-03-05 |
| CZ2002483A3 (cs) | 2002-05-15 |
| US20030055229A1 (en) | 2003-03-20 |
| CN1368966A (zh) | 2002-09-11 |
| TR200202474T2 (tr) | 2003-01-21 |
| ATE294166T1 (de) | 2005-05-15 |
| CN1626525A (zh) | 2005-06-15 |
| EP1202979A1 (en) | 2002-05-08 |
| US6265553B1 (en) | 2001-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20050214 |