RS64579B1 - Nova heterociklična jedinjenja - Google Patents

Nova heterociklična jedinjenja

Info

Publication number
RS64579B1
RS64579B1 RS20230788A RSP20230788A RS64579B1 RS 64579 B1 RS64579 B1 RS 64579B1 RS 20230788 A RS20230788 A RS 20230788A RS P20230788 A RSP20230788 A RS P20230788A RS 64579 B1 RS64579 B1 RS 64579B1
Authority
RS
Serbia
Prior art keywords
heterocyclic compounds
new heterocyclic
new
compounds
heterocyclic
Prior art date
Application number
RS20230788A
Other languages
English (en)
Inventor
Bernd Kuhn
Uwe Grether
Benoit Hornsperger
Hans Richter
Carsten Kroll
Zbinden Katrin Groebke
Fionn O`Hara
Didier Rombach
Marius Daniel Rinaldo Lutz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of RS64579B1 publication Critical patent/RS64579B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
RS20230788A 2018-11-22 2019-11-20 Nova heterociklična jedinjenja RS64579B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18207725 2018-11-22
EP19809026.8A EP3883936B1 (en) 2018-11-22 2019-11-20 New heterocyclic compounds
PCT/EP2019/081870 WO2020104494A1 (en) 2018-11-22 2019-11-20 New heterocyclic compounds

Publications (1)

Publication Number Publication Date
RS64579B1 true RS64579B1 (sr) 2023-10-31

Family

ID=64453331

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20230788A RS64579B1 (sr) 2018-11-22 2019-11-20 Nova heterociklična jedinjenja

Country Status (31)

Country Link
US (1) US20210387999A1 (sr)
EP (1) EP3883936B1 (sr)
JP (1) JP7444882B2 (sr)
KR (1) KR20210094540A (sr)
CN (1) CN113166170A (sr)
AR (1) AR117139A1 (sr)
AU (1) AU2019383500A1 (sr)
BR (1) BR112021009348A2 (sr)
CA (1) CA3119506A1 (sr)
CL (1) CL2021001330A1 (sr)
CO (1) CO2021007056A2 (sr)
CR (1) CR20210247A (sr)
DK (1) DK3883936T3 (sr)
ES (1) ES2955037T3 (sr)
FI (1) FI3883936T3 (sr)
HR (1) HRP20231083T1 (sr)
HU (1) HUE062913T2 (sr)
IL (1) IL283333B2 (sr)
LT (1) LT3883936T (sr)
MA (1) MA55131B1 (sr)
MX (1) MX2021005714A (sr)
PE (1) PE20211870A1 (sr)
PH (1) PH12021551167A1 (sr)
PL (1) PL3883936T3 (sr)
PT (1) PT3883936T (sr)
RS (1) RS64579B1 (sr)
SG (1) SG11202104206SA (sr)
SI (1) SI3883936T1 (sr)
TW (1) TWI825227B (sr)
UA (1) UA128505C2 (sr)
WO (1) WO2020104494A1 (sr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR114136A1 (es) 2017-10-10 2020-07-29 Hoffmann La Roche Compuestos heterocíclicos
WO2019105915A1 (en) 2017-11-28 2019-06-06 F. Hoffmann-La Roche Ag New heterocyclic compounds
TW201938164A (zh) 2018-01-08 2019-10-01 瑞士商赫孚孟拉羅股份公司 新穎雜環化合物
RU2769507C1 (ru) 2018-08-13 2022-04-01 Ф. Хоффманн-Ля Рош Аг Новые гетероциклические соединения как ингибиторы моноацилглицеринлипазы
US20210094971A1 (en) * 2019-09-09 2021-04-01 Hoffmann-La Roche Inc. Heterocyclic compounds
KR20220062515A (ko) * 2019-09-12 2022-05-17 에프. 호프만-라 로슈 아게 Magl 억제제로서 4,4a,5,7,8,8a-헥사피리도[4,3-b][1,4]옥사진-3-온 화합물
WO2022049134A1 (en) 2020-09-03 2022-03-10 F. Hoffmann-La Roche Ag Heterocyclic compounds
EP4215526A4 (en) * 2020-09-18 2024-10-16 Shanghai Pharmaceuticals Holding Co Ltd HETEROCYCLIC CARBONYL COMPOUND AND ITS USE
JP2024505261A (ja) 2021-01-29 2024-02-05 セディラ・セラピューティクス・インコーポレイテッド Cdk2阻害剤およびその使用方法
TW202317560A (zh) 2021-06-26 2023-05-01 美商賽迪拉治療股份有限公司 Cdk2抑制劑及其使用方法
WO2023130043A1 (en) * 2021-12-29 2023-07-06 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment of anxiety
WO2023130050A1 (en) * 2021-12-29 2023-07-06 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment and management of pain
AR128333A1 (es) * 2022-01-25 2024-04-17 Hoffmann La Roche Nuevos compuestos heterociclicos
WO2023247670A1 (en) * 2022-06-24 2023-12-28 F. Hoffmann-La Roche Ag New heterocyclic-carbonyl-cyclic compounds as magl inhibitors
WO2024033277A1 (en) 2022-08-08 2024-02-15 F. Hoffmann-La Roche Ag New heterocyclic compounds
WO2024033479A1 (en) * 2022-08-11 2024-02-15 Remynd N.V. (aza)spiroheptane derivatives for the treatment of neurodegenerative disorders
WO2024061853A1 (en) * 2022-09-20 2024-03-28 F. Hoffmann-La Roche Ag Fluorescent probes for magl
WO2024088922A1 (en) * 2022-10-24 2024-05-02 F. Hoffmann-La Roche Ag Heterocyclic compounds as inhibitors of monoacylglycerol lipase (magl)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7579495B2 (en) 2003-12-19 2009-08-25 Momentive Performance Materials Inc. Active-releasing cyclic siloxanes
KR101481872B1 (ko) 2009-09-10 2015-01-12 에프. 호프만-라 로슈 아게 Jak의 억제제
WO2011059118A1 (ko) 2009-11-10 2011-05-19 Kim Hyun Jeen 후각인지능력 검사 시스템
JP5990297B2 (ja) 2015-03-03 2016-09-14 タイヨーエレック株式会社 遊技機
WO2016158956A1 (ja) * 2015-03-30 2016-10-06 武田薬品工業株式会社 複素環化合物
JP6703553B2 (ja) 2015-05-21 2020-06-03 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Pad4阻害剤としてのベンゾイミダゾール誘導体
EP3328849B9 (en) 2015-07-31 2021-01-06 Pfizer Inc. 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives and 1,1,1-trifluoro-4-hydroxybutan-2-yl carbamate derivatives as magl inhibitors
WO2017087858A1 (en) * 2015-11-20 2017-05-26 Abide Therapeutics, Inc. Pyrazole compounds and methods of making and using same

Also Published As

Publication number Publication date
HRP20231083T1 (hr) 2023-12-22
EP3883936A1 (en) 2021-09-29
ES2955037T3 (es) 2023-11-28
MA55131B1 (fr) 2023-10-31
DK3883936T3 (da) 2023-09-18
EP3883936B1 (en) 2023-07-12
MA55131A (fr) 2022-03-02
CO2021007056A2 (es) 2021-06-10
LT3883936T (lt) 2023-09-25
PE20211870A1 (es) 2021-09-21
IL283333B2 (en) 2024-08-01
AR117139A1 (es) 2021-07-14
IL283333A (en) 2021-07-29
SI3883936T1 (sl) 2023-10-30
JP7444882B2 (ja) 2024-03-06
MX2021005714A (es) 2021-07-21
TW202039513A (zh) 2020-11-01
CL2021001330A1 (es) 2021-10-29
PT3883936T (pt) 2023-09-04
BR112021009348A2 (pt) 2021-08-10
HUE062913T2 (hu) 2023-12-28
CN113166170A (zh) 2021-07-23
PL3883936T3 (pl) 2023-11-20
KR20210094540A (ko) 2021-07-29
CR20210247A (es) 2021-06-08
JP2022507919A (ja) 2022-01-18
WO2020104494A1 (en) 2020-05-28
TWI825227B (zh) 2023-12-11
SG11202104206SA (en) 2021-06-29
PH12021551167A1 (en) 2021-10-25
CA3119506A1 (en) 2020-05-28
AU2019383500A1 (en) 2021-05-27
FI3883936T3 (fi) 2023-09-05
UA128505C2 (uk) 2024-07-31
US20210387999A1 (en) 2021-12-16
IL283333B1 (en) 2024-04-01

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