DK3883936T3 - Nye heterocykliske forbindelser - Google Patents

Nye heterocykliske forbindelser Download PDF

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Publication number
DK3883936T3
DK3883936T3 DK19809026.8T DK19809026T DK3883936T3 DK 3883936 T3 DK3883936 T3 DK 3883936T3 DK 19809026 T DK19809026 T DK 19809026T DK 3883936 T3 DK3883936 T3 DK 3883936T3
Authority
DK
Denmark
Prior art keywords
heterocyclic compounds
new heterocyclic
new
compounds
heterocyclic
Prior art date
Application number
DK19809026.8T
Other languages
English (en)
Inventor
Bernd Kuhn
Uwe Grether
Benoit Hornsperger
Hans Richter
Carsten Kroll
Zbinden Katrin Groebke
Fionn O`Hara
Didier Rombach
Marius Daniel Rinaldo Lutz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK3883936T3 publication Critical patent/DK3883936T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
DK19809026.8T 2018-11-22 2019-11-20 Nye heterocykliske forbindelser DK3883936T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18207725 2018-11-22
PCT/EP2019/081870 WO2020104494A1 (en) 2018-11-22 2019-11-20 New heterocyclic compounds

Publications (1)

Publication Number Publication Date
DK3883936T3 true DK3883936T3 (da) 2023-09-18

Family

ID=64453331

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19809026.8T DK3883936T3 (da) 2018-11-22 2019-11-20 Nye heterocykliske forbindelser

Country Status (30)

Country Link
US (1) US20210387999A1 (da)
EP (1) EP3883936B1 (da)
JP (1) JP7444882B2 (da)
KR (1) KR20210094540A (da)
CN (1) CN113166170A (da)
AR (1) AR117139A1 (da)
AU (1) AU2019383500A1 (da)
BR (1) BR112021009348A2 (da)
CA (1) CA3119506A1 (da)
CL (1) CL2021001330A1 (da)
CO (1) CO2021007056A2 (da)
CR (1) CR20210247A (da)
DK (1) DK3883936T3 (da)
ES (1) ES2955037T3 (da)
FI (1) FI3883936T3 (da)
HR (1) HRP20231083T1 (da)
HU (1) HUE062913T2 (da)
IL (1) IL283333B1 (da)
LT (1) LT3883936T (da)
MA (1) MA55131B1 (da)
MX (1) MX2021005714A (da)
PE (1) PE20211870A1 (da)
PH (1) PH12021551167A1 (da)
PL (1) PL3883936T3 (da)
PT (1) PT3883936T (da)
RS (1) RS64579B1 (da)
SG (1) SG11202104206SA (da)
SI (1) SI3883936T1 (da)
TW (1) TWI825227B (da)
WO (1) WO2020104494A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR114136A1 (es) 2017-10-10 2020-07-29 Hoffmann La Roche Compuestos heterocíclicos
EP3717477B1 (en) 2017-11-28 2022-07-20 F. Hoffmann-La Roche AG New heterocyclic compounds
WO2019134985A1 (en) 2018-01-08 2019-07-11 F. Hoffmann-La Roche Ag Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
EP3837263A1 (en) 2018-08-13 2021-06-23 F. Hoffmann-La Roche AG New heterocyclic compounds as monoacylglycerol lipase inhibitors
US20210094971A1 (en) * 2019-09-09 2021-04-01 Hoffmann-La Roche Inc. Heterocyclic compounds
EP4028403B1 (en) 2019-09-12 2023-11-22 F. Hoffmann-La Roche AG 4,4a,5,7,8,8a-hexapyrido[4,3-b][1,4]oxazin-3-one compounds as magl inhibitors
US20240101552A1 (en) * 2020-09-18 2024-03-28 Shanghai Pharmaceuticals Holding Co., Ltd. Carbonyl heterocyclic compound and application thereof
WO2023130043A1 (en) * 2021-12-29 2023-07-06 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment of anxiety
WO2023130050A1 (en) * 2021-12-29 2023-07-06 Psy Therapeutics, Inc. Monoacylglycerol lipase inhibitors and use thereof for the treatment and management of pain
AR128333A1 (es) * 2022-01-25 2024-04-17 Hoffmann La Roche Nuevos compuestos heterociclicos
WO2023247670A1 (en) * 2022-06-24 2023-12-28 F. Hoffmann-La Roche Ag New heterocyclic-carbonyl-cyclic compounds as magl inhibitors
WO2024033277A1 (en) 2022-08-08 2024-02-15 F. Hoffmann-La Roche Ag New heterocyclic compounds
WO2024033479A1 (en) * 2022-08-11 2024-02-15 Remynd N.V. (aza)spiroheptane derivatives for the treatment of neurodegenerative disorders
WO2024061853A1 (en) * 2022-09-20 2024-03-28 F. Hoffmann-La Roche Ag Fluorescent probes for magl
WO2024088922A1 (en) * 2022-10-24 2024-05-02 F. Hoffmann-La Roche Ag Heterocyclic compounds as inhibitors of monoacylglycerol lipase (magl)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7579495B2 (en) 2003-12-19 2009-08-25 Momentive Performance Materials Inc. Active-releasing cyclic siloxanes
KR101481872B1 (ko) 2009-09-10 2015-01-12 에프. 호프만-라 로슈 아게 Jak의 억제제
WO2011059118A1 (ko) 2009-11-10 2011-05-19 Kim Hyun Jeen 후각인지능력 검사 시스템
JP5990297B2 (ja) 2015-03-03 2016-09-14 タイヨーエレック株式会社 遊技機
WO2016158956A1 (ja) * 2015-03-30 2016-10-06 武田薬品工業株式会社 複素環化合物
CN107849015B (zh) 2015-05-21 2021-03-19 葛兰素知识产权发展有限公司 作为pad4抑制剂的苯并咪唑衍生物
BR112018000041A2 (pt) 2015-07-31 2018-09-04 Pfizer Inc. Derivados de carbamato de 1,1,1-trifluoro-3- hidroxipropan-2-ila e derivados de carbamato de 1,1,1-trifluoro-4-hidroxibutan-2-ila como inibidores de magl
US10385057B2 (en) 2015-11-20 2019-08-20 Lundbeck La Jolla Research Center, Inc. Pyrazole compounds and methods of making and using same

Also Published As

Publication number Publication date
ES2955037T3 (es) 2023-11-28
RS64579B1 (sr) 2023-10-31
JP7444882B2 (ja) 2024-03-06
CL2021001330A1 (es) 2021-10-29
US20210387999A1 (en) 2021-12-16
AU2019383500A1 (en) 2021-05-27
KR20210094540A (ko) 2021-07-29
AR117139A1 (es) 2021-07-14
MA55131B1 (fr) 2023-10-31
FI3883936T3 (fi) 2023-09-05
EP3883936A1 (en) 2021-09-29
BR112021009348A2 (pt) 2021-08-10
CO2021007056A2 (es) 2021-06-10
TW202039513A (zh) 2020-11-01
CN113166170A (zh) 2021-07-23
WO2020104494A1 (en) 2020-05-28
MA55131A (fr) 2022-03-02
TWI825227B (zh) 2023-12-11
LT3883936T (lt) 2023-09-25
EP3883936B1 (en) 2023-07-12
PL3883936T3 (pl) 2023-11-20
PE20211870A1 (es) 2021-09-21
PT3883936T (pt) 2023-09-04
PH12021551167A1 (en) 2021-10-25
SI3883936T1 (sl) 2023-10-30
CR20210247A (es) 2021-06-08
HRP20231083T1 (hr) 2023-12-22
IL283333B1 (en) 2024-04-01
SG11202104206SA (en) 2021-06-29
CA3119506A1 (en) 2020-05-28
JP2022507919A (ja) 2022-01-18
MX2021005714A (es) 2021-07-21
HUE062913T2 (hu) 2023-12-28
IL283333A (en) 2021-07-29

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