RS63551B1 - Poboljšani postupak za proizvodnju crm na visokom nivou - Google Patents

Poboljšani postupak za proizvodnju crm na visokom nivou

Info

Publication number
RS63551B1
RS63551B1 RS20220813A RSP20220813A RS63551B1 RS 63551 B1 RS63551 B1 RS 63551B1 RS 20220813 A RS20220813 A RS 20220813A RS P20220813 A RSP20220813 A RS P20220813A RS 63551 B1 RS63551 B1 RS 63551B1
Authority
RS
Serbia
Prior art keywords
crm
high level
improved method
level production
production
Prior art date
Application number
RS20220813A
Other languages
English (en)
Inventor
Balamurali Masilamani
Rajan Sriraman
Mandar Shirish Dixit
Deviprasanna Chakka
Satyam Naidu Sureddi
Ramesh Venkat Matur
Narender Dev Mantena
Mahima Datla
Original Assignee
Biological E Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biological E Ltd filed Critical Biological E Ltd
Publication of RS63551B1 publication Critical patent/RS63551B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/05Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Electron Tubes, Discharge Lamp Vessels, Lead-In Wires, And The Like (AREA)
  • Forging (AREA)
RS20220813A 2017-04-22 2018-04-19 Poboljšani postupak za proizvodnju crm na visokom nivou RS63551B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201741014335 2017-04-22
PCT/IN2018/050235 WO2018193475A2 (en) 2017-04-22 2018-04-19 An improved method for high level production of crm
EP18773868.7A EP3612553B1 (en) 2017-04-22 2018-04-19 An improved method for high level production of crm

Publications (1)

Publication Number Publication Date
RS63551B1 true RS63551B1 (sr) 2022-09-30

Family

ID=63678648

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20220813A RS63551B1 (sr) 2017-04-22 2018-04-19 Poboljšani postupak za proizvodnju crm na visokom nivou

Country Status (30)

Country Link
US (1) US11098089B2 (sr)
EP (1) EP3612553B1 (sr)
JP (1) JP7161493B2 (sr)
KR (1) KR102637436B1 (sr)
CN (1) CN110741013B (sr)
AU (1) AU2018255959B2 (sr)
BR (1) BR112019022093A2 (sr)
CA (1) CA3060723A1 (sr)
CL (1) CL2019003003A1 (sr)
CO (1) CO2019011643A2 (sr)
CU (1) CU24668B1 (sr)
DK (1) DK3612553T3 (sr)
EA (1) EA201992527A1 (sr)
ES (1) ES2926535T3 (sr)
HR (1) HRP20221060T1 (sr)
HU (1) HUE059629T2 (sr)
IL (1) IL270075B2 (sr)
LT (1) LT3612553T (sr)
MX (1) MX2019012563A (sr)
MY (1) MY194242A (sr)
PH (1) PH12019550214A1 (sr)
PL (1) PL3612553T3 (sr)
PT (1) PT3612553T (sr)
RS (1) RS63551B1 (sr)
SA (1) SA519410306B1 (sr)
SG (1) SG11201909765XA (sr)
SI (1) SI3612553T1 (sr)
UA (1) UA127497C2 (sr)
WO (1) WO2018193475A2 (sr)
ZA (1) ZA201906270B (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021005425A2 (pt) 2018-09-23 2021-06-15 Biological E Limited polissacarídeos capsulares purificados de streptococcus pneumoniae
CN113755380A (zh) * 2021-09-23 2021-12-07 艾美卫信生物药业(浙江)有限公司 一种发酵生产白喉毒素crm197蛋白的菌种培养基、配制方法以及菌种复苏培养方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0616034B1 (en) * 1993-03-05 2004-10-20 Wyeth Holdings Corporation Plasmid for production of CRM protein and diphtheria toxin
EP2199382A3 (en) 1997-05-28 2010-09-22 Novartis Vaccines and Diagnostics S.r.l. Culture medium with yeast or soy bean extract as aminoacid source and no protein complexes of animal origin
US20040087020A1 (en) 1997-05-28 2004-05-06 Chiron S.P.A. Culture medium with yeast or soy bean extract as amino acid source and no protein complexes of animal origin
GB9904582D0 (en) 1999-02-26 1999-04-21 Nycomed Imaging As Process
KR20060133994A (ko) * 2003-12-12 2006-12-27 사노피 파스퇴르 리미티드 디프테리아 독소의 생산 방법
GB0505996D0 (en) * 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
AU2010201410B2 (en) 2010-03-30 2015-04-30 Pelican Technology Holdings, Inc. High level expression of recombinant CRM197
GB2495341B (en) * 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
FR2992656B1 (fr) * 2012-07-02 2016-10-07 Sanofi Pasteur Procede de production d'antigenes haemophilus influenzae type b
ITMI20130142A1 (it) * 2013-01-31 2014-08-01 Biosynth Srl Vaccini glicoconiugati comprendenti unita' di base di un costrutto molecolare esprimente epitopi multipli incorporati
EP3113800B1 (en) 2014-03-03 2024-06-19 Scarab Genomics, LLC Enhanced production of recombinant crm197 in e. coli

Also Published As

Publication number Publication date
WO2018193475A3 (en) 2018-12-27
KR20200010218A (ko) 2020-01-30
SG11201909765XA (en) 2019-11-28
WO2018193475A2 (en) 2018-10-25
US20200277341A1 (en) 2020-09-03
MX2019012563A (es) 2019-12-02
US11098089B2 (en) 2021-08-24
EA201992527A1 (ru) 2020-02-28
CL2019003003A1 (es) 2020-02-14
EP3612553A2 (en) 2020-02-26
SA519410306B1 (ar) 2022-02-02
AU2018255959A1 (en) 2019-11-14
CO2019011643A2 (es) 2020-01-17
HRP20221060T1 (hr) 2022-11-11
CA3060723A1 (en) 2018-10-25
AU2018255959A8 (en) 2022-02-17
DK3612553T3 (da) 2022-08-29
CU20190083A7 (es) 2020-10-20
PT3612553T (pt) 2022-09-08
IL270075B2 (en) 2024-06-01
CN110741013A (zh) 2020-01-31
ZA201906270B (en) 2020-07-29
BR112019022093A2 (pt) 2020-05-05
UA127497C2 (uk) 2023-09-13
PH12019550214A1 (en) 2020-09-14
CU24668B1 (es) 2023-07-12
JP2020517274A (ja) 2020-06-18
KR102637436B1 (ko) 2024-02-15
MY194242A (en) 2022-11-24
EP3612553B1 (en) 2022-06-08
ES2926535T3 (es) 2022-10-26
SI3612553T1 (sl) 2022-11-30
JP7161493B2 (ja) 2022-10-26
LT3612553T (lt) 2022-09-26
IL270075A (sr) 2019-12-31
PL3612553T3 (pl) 2022-11-07
IL270075B1 (en) 2024-02-01
CN110741013B (zh) 2023-08-08
HUE059629T2 (hu) 2022-12-28
AU2018255959B2 (en) 2022-02-17

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