RS60795B1 - Vezujući molekuli specifični za il-21 i njihove upotrebe - Google Patents
Vezujući molekuli specifični za il-21 i njihove upotrebeInfo
- Publication number
- RS60795B1 RS60795B1 RS20201046A RSP20201046A RS60795B1 RS 60795 B1 RS60795 B1 RS 60795B1 RS 20201046 A RS20201046 A RS 20201046A RS P20201046 A RSP20201046 A RS P20201046A RS 60795 B1 RS60795 B1 RS 60795B1
- Authority
- RS
- Serbia
- Prior art keywords
- binding molecules
- molecules specific
- specific
- binding
- molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461976684P | 2014-04-08 | 2014-04-08 | |
PCT/US2015/024650 WO2015157238A2 (en) | 2014-04-08 | 2015-04-07 | Binding molecules specific for il-21 and uses thereof |
EP15776002.6A EP3128997B1 (en) | 2014-04-08 | 2015-04-07 | Binding molecules specific for il-21 and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS60795B1 true RS60795B1 (sr) | 2020-10-30 |
Family
ID=54288526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20201046A RS60795B1 (sr) | 2014-04-08 | 2015-04-07 | Vezujući molekuli specifični za il-21 i njihove upotrebe |
Country Status (23)
Country | Link |
---|---|
US (4) | US10022443B2 (sr) |
EP (2) | EP3128997B1 (sr) |
KR (1) | KR102546611B1 (sr) |
CN (2) | CN111560071B (sr) |
AU (2) | AU2015244025B2 (sr) |
CA (2) | CA2948275C (sr) |
CY (1) | CY1123275T1 (sr) |
DK (1) | DK3128997T3 (sr) |
ES (1) | ES2814150T3 (sr) |
HR (1) | HRP20201377T1 (sr) |
HU (1) | HUE051676T2 (sr) |
IL (2) | IL248709B (sr) |
LT (1) | LT3128997T (sr) |
MA (2) | MA50678A (sr) |
PL (1) | PL3128997T3 (sr) |
PT (1) | PT3128997T (sr) |
RS (1) | RS60795B1 (sr) |
RU (1) | RU2708336C2 (sr) |
SG (2) | SG11201609178SA (sr) |
SI (1) | SI3128997T1 (sr) |
TW (1) | TWI665214B (sr) |
WO (1) | WO2015157238A2 (sr) |
ZA (1) | ZA201707489B (sr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017223283A1 (en) | 2016-06-22 | 2017-12-28 | Icahn School Of Medicine At Mount Sinai | Hcv core and minicore binding molecules |
AU2017394032B8 (en) | 2017-01-21 | 2020-10-22 | Guangzhou Hanfang Pharmaceutical Co., Ltd. | Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome |
DK3661954T3 (da) | 2017-08-03 | 2022-04-19 | Amgen Inc | Interleukin-21-muteiner og fremgangsmåder til behandling |
CN109503715B (zh) * | 2017-09-15 | 2023-12-15 | 科济生物医药(上海)有限公司 | Il-4r的融合蛋白及其应用 |
CR20200330A (es) | 2018-01-12 | 2020-12-23 | Amgen Inc | Anticuerpos anti-pd-1 y métodos de tratamiento |
KR20220020879A (ko) | 2019-06-12 | 2022-02-21 | 에스크진 파마, 아이엔씨. | 새로운 il-15 프로드럭 및 이를 사용하는 방법 |
US20220289822A1 (en) | 2019-08-21 | 2022-09-15 | AskGene Pharma, Inc. | Novel il-21 prodrugs and methods of use thereof |
CN113321729B (zh) * | 2021-07-01 | 2022-08-30 | 东大生物技术(苏州)有限公司 | 一组il-12单克隆抗体及其医药用途 |
CN116554323B (zh) * | 2023-04-27 | 2024-02-27 | 中南大学湘雅二医院 | 人源化抗il21抗体的开发和应用 |
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DE3546807C2 (sr) | 1985-03-30 | 1991-03-28 | Marc Genf/Geneve Ch Ballivet | |
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US5618920A (en) | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
DE3600905A1 (de) | 1986-01-15 | 1987-07-16 | Ant Nachrichtentech | Verfahren zum dekodieren von binaersignalen sowie viterbi-dekoder und anwendungen |
US5681718A (en) | 1986-03-14 | 1997-10-28 | Celltech Limited | Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5763192A (en) | 1986-11-20 | 1998-06-09 | Ixsys, Incorporated | Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique |
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CA2057923A1 (en) | 1989-05-16 | 1990-11-17 | William D. Huse | Co-expression of heteromeric receptors |
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GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
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US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
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TWI510996B (zh) | 2013-10-03 | 2015-12-01 | Acer Inc | 控制觸控面板的方法以及使用該方法的可攜式電腦 |
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US9816280B1 (en) | 2016-11-02 | 2017-11-14 | Matthew Reitnauer | Portable floor |
-
2015
- 2015-04-07 LT LTEP15776002.6T patent/LT3128997T/lt unknown
- 2015-04-07 KR KR1020167031140A patent/KR102546611B1/ko active IP Right Grant
- 2015-04-07 ES ES15776002T patent/ES2814150T3/es active Active
- 2015-04-07 CN CN202010302182.3A patent/CN111560071B/zh active Active
- 2015-04-07 WO PCT/US2015/024650 patent/WO2015157238A2/en active Application Filing
- 2015-04-07 SI SI201531333T patent/SI3128997T1/sl unknown
- 2015-04-07 SG SG11201609178SA patent/SG11201609178SA/en unknown
- 2015-04-07 RU RU2016143378A patent/RU2708336C2/ru active
- 2015-04-07 EP EP15776002.6A patent/EP3128997B1/en active Active
- 2015-04-07 HU HUE15776002A patent/HUE051676T2/hu unknown
- 2015-04-07 MA MA050678A patent/MA50678A/fr unknown
- 2015-04-07 EP EP20160066.5A patent/EP3689325A1/en active Pending
- 2015-04-07 US US15/305,093 patent/US10022443B2/en active Active
- 2015-04-07 PL PL15776002T patent/PL3128997T3/pl unknown
- 2015-04-07 DK DK15776002.6T patent/DK3128997T3/da active
- 2015-04-07 CN CN201580030200.4A patent/CN106794129B/zh active Active
- 2015-04-07 MA MA39821A patent/MA39821B1/fr unknown
- 2015-04-07 AU AU2015244025A patent/AU2015244025B2/en active Active
- 2015-04-07 RS RS20201046A patent/RS60795B1/sr unknown
- 2015-04-07 CA CA2948275A patent/CA2948275C/en active Active
- 2015-04-07 PT PT157760026T patent/PT3128997T/pt unknown
- 2015-04-07 SG SG10201913627TA patent/SG10201913627TA/en unknown
- 2015-04-07 CA CA3208721A patent/CA3208721A1/en active Pending
- 2015-04-08 TW TW104111328A patent/TWI665214B/zh active
-
2016
- 2016-11-02 IL IL248709A patent/IL248709B/en active IP Right Grant
-
2017
- 2017-11-06 ZA ZA2017/07489A patent/ZA201707489B/en unknown
-
2018
- 2018-06-11 US US16/004,795 patent/US10588969B2/en active Active
-
2019
- 2019-04-09 AU AU2019202447A patent/AU2019202447B2/en active Active
-
2020
- 2020-02-05 US US16/782,541 patent/US11529415B2/en active Active
- 2020-03-26 IL IL273641A patent/IL273641B/en active IP Right Grant
- 2020-08-24 CY CY20201100787T patent/CY1123275T1/el unknown
- 2020-08-28 HR HRP20201377TT patent/HRP20201377T1/hr unknown
-
2022
- 2022-12-19 US US18/084,364 patent/US20230201346A1/en active Pending
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