SG11201609178SA - Binding molecules specific for il-21 and uses thereof - Google Patents

Binding molecules specific for il-21 and uses thereof

Info

Publication number
SG11201609178SA
SG11201609178SA SG11201609178SA SG11201609178SA SG11201609178SA SG 11201609178S A SG11201609178S A SG 11201609178SA SG 11201609178S A SG11201609178S A SG 11201609178SA SG 11201609178S A SG11201609178S A SG 11201609178SA SG 11201609178S A SG11201609178S A SG 11201609178SA
Authority
SG
Singapore
Prior art keywords
binding molecules
molecules specific
specific
binding
molecules
Prior art date
Application number
SG11201609178SA
Inventor
Catherine Ettinger
Jodi Karnell
Melissa Damschroder
Partha Chowdhury
Xiaodong Xiao
Ping Tsui
Reena Varkey
Stacey Drabic
Laura Carter
Ronald Herbst
Qun Du
Brian Michael Naiman
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54288526&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201609178S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of SG11201609178SA publication Critical patent/SG11201609178SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201609178SA 2014-04-08 2015-04-07 Binding molecules specific for il-21 and uses thereof SG11201609178SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461976684P 2014-04-08 2014-04-08
PCT/US2015/024650 WO2015157238A2 (en) 2014-04-08 2015-04-07 Binding molecules specific for il-21 and uses thereof

Publications (1)

Publication Number Publication Date
SG11201609178SA true SG11201609178SA (en) 2016-12-29

Family

ID=54288526

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913627TA SG10201913627TA (en) 2014-04-08 2015-04-07 Binding molecules specific for il-21 and uses thereof
SG11201609178SA SG11201609178SA (en) 2014-04-08 2015-04-07 Binding molecules specific for il-21 and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201913627TA SG10201913627TA (en) 2014-04-08 2015-04-07 Binding molecules specific for il-21 and uses thereof

Country Status (23)

Country Link
US (4) US10022443B2 (en)
EP (2) EP3128997B1 (en)
KR (1) KR102546611B1 (en)
CN (2) CN106794129B (en)
AU (2) AU2015244025B2 (en)
CA (2) CA2948275C (en)
CY (1) CY1123275T1 (en)
DK (1) DK3128997T3 (en)
ES (1) ES2814150T3 (en)
HR (1) HRP20201377T1 (en)
HU (1) HUE051676T2 (en)
IL (2) IL248709B (en)
LT (1) LT3128997T (en)
MA (2) MA39821B1 (en)
PL (1) PL3128997T3 (en)
PT (1) PT3128997T (en)
RS (1) RS60795B1 (en)
RU (1) RU2708336C2 (en)
SG (2) SG10201913627TA (en)
SI (1) SI3128997T1 (en)
TW (1) TWI665214B (en)
WO (1) WO2015157238A2 (en)
ZA (1) ZA201707489B (en)

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WO2017223283A1 (en) 2016-06-22 2017-12-28 Icahn School Of Medicine At Mount Sinai Hcv core and minicore binding molecules
US20180325931A1 (en) 2017-01-21 2018-11-15 Ningbo Zhiming Biotechnology Co., Ltd. Use of paeoniflorin-6'-o-benzenesulfonate in treatment of sjögren's syndrome
WO2019028316A1 (en) 2017-08-03 2019-02-07 Amgen Inc. Interleukin-21 muteins and methods of treatment
CN109503715B (en) * 2017-09-15 2023-12-15 科济生物医药（上海）有限公司 Fusion proteins of IL-4R and uses thereof
MX2020007291A (en) 2018-01-12 2020-09-10 Amgen Inc Anti-pd-1 antibodies and methods of treatment.
KR20220020879A (en) 2019-06-12 2022-02-21 에스크진 파마, 아이엔씨. New IL-15 prodrugs and how to use them
US20220289822A1 (en) 2019-08-21 2022-09-15 AskGene Pharma, Inc. Novel il-21 prodrugs and methods of use thereof
CN113321729B (en) * 2021-07-01 2022-08-30 东大生物技术(苏州)有限公司 Group of IL-12 monoclonal antibodies and medical application thereof
CN116554323B (en) * 2023-04-27 2024-02-27 中南大学湘雅二医院 Development and use of humanized anti-IL 21 antibodies

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Also Published As

Publication number Publication date
EP3128997A2 (en) 2017-02-15
IL248709B (en) 2020-08-31
US10022443B2 (en) 2018-07-17
CN111560071A (en) 2020-08-21
BR112016029734A2 (en) 2021-11-16
PL3128997T3 (en) 2020-12-28
MA39821B1 (en) 2020-09-30
TWI665214B (en) 2019-07-11
CA2948275A1 (en) 2015-10-15
AU2015244025A1 (en) 2016-11-17
CA3208721A1 (en) 2015-10-15
MA39821A (en) 2017-02-15
EP3128997B1 (en) 2020-08-05
PT3128997T (en) 2020-09-04
WO2015157238A2 (en) 2015-10-15
AU2019202447A1 (en) 2019-05-02
HRP20201377T1 (en) 2021-02-19
LT3128997T (en) 2020-10-12
RU2016143378A (en) 2018-05-08
CY1123275T1 (en) 2021-12-31
NZ725735A (en) 2023-09-29
KR102546611B1 (en) 2023-06-22
AU2019202447B2 (en) 2020-09-10
RS60795B1 (en) 2020-10-30
RU2708336C2 (en) 2019-12-05
IL248709A0 (en) 2017-03-30
IL273641A (en) 2020-05-31
EP3689325A1 (en) 2020-08-05
AU2015244025B2 (en) 2019-03-21
US20180318416A1 (en) 2018-11-08
SG10201913627TA (en) 2020-03-30
WO2015157238A3 (en) 2015-12-10
ES2814150T3 (en) 2021-03-26
US20170173149A1 (en) 2017-06-22
US11529415B2 (en) 2022-12-20
CN111560071B (en) 2023-09-05
MA50678A (en) 2020-08-05
RU2016143378A3 (en) 2019-01-21
CA2948275C (en) 2023-10-17
US20230201346A1 (en) 2023-06-29
NZ762893A (en) 2023-10-27
SI3128997T1 (en) 2020-11-30
EP3128997A4 (en) 2017-12-13
DK3128997T3 (en) 2020-08-24
HUE051676T2 (en) 2021-03-29
IL273641B (en) 2021-04-29
TW201620934A (en) 2016-06-16
US20200164069A1 (en) 2020-05-28
KR20170018814A (en) 2017-02-20
ZA201707489B (en) 2019-06-26
CN106794129A (en) 2017-05-31
CN106794129B (en) 2020-05-12
US10588969B2 (en) 2020-03-17

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