RS52777B - Terapijski sistem sa trenutnim otpuštanjem za poboljšanu oralnu apsorpciju 7-[(e)-tert-butiloksiiminometil] kamptotecina - Google Patents

Terapijski sistem sa trenutnim otpuštanjem za poboljšanu oralnu apsorpciju 7-[(e)-tert-butiloksiiminometil] kamptotecina

Info

Publication number
RS52777B
RS52777B RS20130196A RSP20130196A RS52777B RS 52777 B RS52777 B RS 52777B RS 20130196 A RS20130196 A RS 20130196A RS P20130196 A RSP20130196 A RS P20130196A RS 52777 B RS52777 B RS 52777B
Authority
RS
Serbia
Prior art keywords
pharmaceutical formulation
formulation according
active principle
capsule
amphiphilic
Prior art date
Application number
RS20130196A
Other languages
English (en)
Serbian (sr)
Inventor
Antonio Longo
Silvia Pace
Massimo Pedrani
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of RS52777B publication Critical patent/RS52777B/sr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RS20130196A 2005-08-04 2006-07-11 Terapijski sistem sa trenutnim otpuštanjem za poboljšanu oralnu apsorpciju 7-[(e)-tert-butiloksiiminometil] kamptotecina RS52777B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000418A ITRM20050418A1 (it) 2005-08-04 2005-08-04 Sistemi terapeutici a rilascio immediato per il migliorato assorbimento orale di 7-[(e)-t-butilossimminometil] camptotecina.
PCT/EP2006/064111 WO2007017331A2 (en) 2005-08-04 2006-07-11 Immediate release therapeutic systems for improved oral absorption of 7- [ (e) -tert-butyloxyiminomethyl] camptothecin

Publications (1)

Publication Number Publication Date
RS52777B true RS52777B (sr) 2013-10-31

Family

ID=37727667

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20130196A RS52777B (sr) 2005-08-04 2006-07-11 Terapijski sistem sa trenutnim otpuštanjem za poboljšanu oralnu apsorpciju 7-[(e)-tert-butiloksiiminometil] kamptotecina

Country Status (19)

Country Link
US (1) US20090053307A1 (enExample)
EP (1) EP1915153B1 (enExample)
JP (1) JP5225084B2 (enExample)
KR (1) KR101301548B1 (enExample)
CN (1) CN101287466B (enExample)
AU (1) AU2006278114B2 (enExample)
BR (1) BRPI0614471A2 (enExample)
CA (1) CA2612080C (enExample)
CY (1) CY1114311T1 (enExample)
DK (1) DK1915153T3 (enExample)
ES (1) ES2407408T3 (enExample)
HR (1) HRP20130364T1 (enExample)
IT (1) ITRM20050418A1 (enExample)
MX (1) MX2008001029A (enExample)
PL (1) PL1915153T3 (enExample)
PT (1) PT1915153E (enExample)
RS (1) RS52777B (enExample)
SI (1) SI1915153T1 (enExample)
WO (1) WO2007017331A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2519193C2 (ru) 2008-09-12 2014-06-10 Критикал Фармасьютикалс Лимитед Усовершенствование всасывания терапевтических средств через слизистые оболочки или кожу
USD618617S1 (en) 2008-12-30 2010-06-29 Multiway Industries (Hk) Ltd. Three way electrical plug
US7892036B2 (en) * 2008-12-30 2011-02-22 Multiway Industries (Hk) Ltd. Electrical wall tap assembly
USD618175S1 (en) 2009-10-15 2010-06-22 Multiway Industries (Hk) Ltd. Three-outlet surge-protected adaptor
USD616823S1 (en) 2009-10-15 2010-06-01 Multiway Industries (Hk) Ltd. Single-outlet surge-protected adaptor
EP2510924B1 (en) * 2009-12-08 2014-10-08 IL Hwa Co., Ltd SOLID DISPERSIONS CONTAINING 20-O-ß-D-GLUCOPYRANOSYL-20(S)-PROTOPANAXADIOL
USD651977S1 (en) 2011-01-10 2012-01-10 Multiway Industries (Hk) Ltd. Multiple outlet electrical connector
CN108066311B (zh) * 2017-12-26 2020-09-08 兆科(广州)肿瘤药物有限公司 一种吉马替康胶囊及其制备方法
USD958079S1 (en) 2019-08-30 2022-07-19 Multiway Industries (Hk) Ltd. 3-way electrical tap
USD955993S1 (en) 2019-08-30 2022-06-28 Multiway Industries (Hk) Ltd. 3-way electrical tap
CN111529497A (zh) * 2020-02-11 2020-08-14 兆科(广州)肿瘤药物有限公司 一种吉马替康药物固体分散组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
NZ502569A (en) * 1997-07-29 2002-05-31 Upjohn Co Self-emulsifying formulation for lipophilic compounds comprising a mixture of diglyceride and monoglyceride in a ratio of 9:1 to 6:4
AR013261A1 (es) * 1997-08-01 2000-12-13 Smithkline Beecham Corp Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
US7030155B2 (en) * 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
PT1044977E (pt) * 1999-03-09 2002-09-30 Sigma Tau Ind Farmaceuti Derivados de camptotecina com actividade antitumoral
AU5273200A (en) * 1999-05-24 2000-12-12 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
CN101480395A (zh) * 2004-03-26 2009-07-15 诺瓦提斯公司 喜树碱衍生物以固定给药方案治疗增生性疾病的用途
GT200500310A (es) * 2004-11-19 2006-06-19 Compuestos organicos
PL1828196T3 (pl) * 2004-12-21 2013-02-28 Sigma Tau Ind Farmaceuti Stereoselektywny sposób wytwarzania i krystaliczne formy kamptotecyny

Also Published As

Publication number Publication date
WO2007017331A3 (en) 2007-09-27
BRPI0614471A2 (pt) 2011-03-29
MX2008001029A (es) 2008-03-14
ES2407408T3 (es) 2013-06-12
HRP20130364T1 (hr) 2013-05-31
CA2612080A1 (en) 2007-02-15
AU2006278114B2 (en) 2011-06-23
US20090053307A1 (en) 2009-02-26
PL1915153T3 (pl) 2013-09-30
CN101287466A (zh) 2008-10-15
EP1915153A2 (en) 2008-04-30
KR20080031945A (ko) 2008-04-11
PT1915153E (pt) 2013-06-05
ITRM20050418A1 (it) 2007-02-05
JP5225084B2 (ja) 2013-07-03
WO2007017331A2 (en) 2007-02-15
KR101301548B1 (ko) 2013-09-06
CA2612080C (en) 2013-09-03
HK1125293A1 (en) 2009-08-07
CN101287466B (zh) 2014-11-05
DK1915153T3 (da) 2013-06-24
JP2009503013A (ja) 2009-01-29
AU2006278114A1 (en) 2007-02-15
CY1114311T1 (el) 2016-08-31
EP1915153B1 (en) 2013-04-10
SI1915153T1 (sl) 2013-06-28

Similar Documents

Publication Publication Date Title
Chaudhari et al. Application of surfactants in solid dispersion technology for improving solubility of poorly water soluble drugs
RS53209B (sr) Farmaceutska kompozicija za inhibitor proteaze virusnog hepatitis c
JP2010510980A (ja) 腸送達系のためのナフトキノンベース化合物を含有する医薬組成物
BRPI0414000B1 (pt) composição farmacêutica sólida oral de liberação prolongada contendo tacrolimus na forma de uma dispersão sólida, forma de dosagem, e, uso da composição farmacêutica
US20090181094A1 (en) Molecular Cage for Sustained Release Control of Pharmaceutical and Cosmetic Agents
RS52777B (sr) Terapijski sistem sa trenutnim otpuštanjem za poboljšanu oralnu apsorpciju 7-[(e)-tert-butiloksiiminometil] kamptotecina
KR100669497B1 (ko) 안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법
CN119421703A (zh) 无定形固体分散体和包含所述无定形固体分散体的药物组合物
WO2016126058A2 (ko) 두타스테라이드 함유 고체 분산체 및 이를 포함하는 조성물
JPH0112729B2 (enExample)
EP2654723A1 (en) Solid pharmaceutical dosage forms comprising tadalafil and methods of preparation thereof
TW202345842A (zh) Protac化合物之醫藥組合物及其用途
CN101106995B (zh) 在非水极性溶剂中增加溶解度的10-羟基喜树碱类化合物的药物制剂
WO2012095151A1 (en) Solid pharmaceutical dosage forms comprising tadalafil and methods of preparation thereof
TWI597063B (zh) 藥物組成物及其製備方法
RS52697B (sr) Stabilna čvrsta disperzija derivata vinka alkaloida i postupak za njenu proizvodnju
HK1125293B (en) Immediate release therapeutic systems for improved oral absorption of 7-[(e)-tertbutyloxyiminoxmethyl] camptothecin
DK2654723T3 (en) Solid pharmaceutical dosage forms comprising tadalafil and processes for their preparation
KR100535228B1 (ko) 란소프라졸함유 경질캅셀제의 제조방법
KR101012903B1 (ko) 나노입자 형성을 이용하는 리세드로네이트 경질캡슐
WO2017045603A1 (zh) 一种含喜树碱衍生物的注射制剂、其注射液、制备和应用
JP5321454B2 (ja) 医薬錠剤の製造法
JP2019085411A (ja) 固形医薬組成物
HK1120437A (en) Pharmaceutical formulation with high stability and dissolution and manufacturing process
KR20040097900A (ko) 슈도에페드린 또는 그의 염의 방출제어형 약제학적 조성물