RS50977B - Replikaciono defektni rnk-virusi kao vakcine - Google Patents
Replikaciono defektni rnk-virusi kao vakcineInfo
- Publication number
- RS50977B RS50977B RSP-2009/0185A RSP20090185A RS50977B RS 50977 B RS50977 B RS 50977B RS P20090185 A RSP20090185 A RS P20090185A RS 50977 B RS50977 B RS 50977B
- Authority
- RS
- Serbia
- Prior art keywords
- replication
- vaccines
- rna viruses
- deficient rna
- loss
- Prior art date
Links
- 230000010076 replication Effects 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 230000002950 deficient Effects 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 101150084044 P gene Proteins 0.000 abstract 1
- 241001493065 dsRNA viruses Species 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Rekombinantni negativni lanac RNK-virusa koji sadrži virusni genom sa mutacijom u genu P, koja dovodi do gubljenja sposobnosti replikacije bez gubljenja sekundarne sposobnosti transkripcije.Prijava sadrži još 36 patentnih zahteva.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005006388A DE102005006388A1 (de) | 2005-02-11 | 2005-02-11 | Replikationsdefiziente RNA-Viren als Impfstoffe |
| PCT/EP2006/001251 WO2006084746A1 (de) | 2005-02-11 | 2006-02-10 | Replikationsdefiziente rna-viren als impfstoffe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS50977B true RS50977B (sr) | 2010-10-31 |
Family
ID=36353666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RSP-2009/0185A RS50977B (sr) | 2005-02-11 | 2006-02-10 | Replikaciono defektni rnk-virusi kao vakcine |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US20090041725A1 (sr) |
| EP (2) | EP2045260A1 (sr) |
| JP (2) | JP5679620B2 (sr) |
| KR (1) | KR101279636B1 (sr) |
| CN (1) | CN101155826B (sr) |
| AT (1) | ATE421529T1 (sr) |
| AU (1) | AU2006212385B2 (sr) |
| BR (1) | BRPI0607487A2 (sr) |
| CA (1) | CA2599036C (sr) |
| DE (2) | DE102005006388A1 (sr) |
| DK (1) | DK1851239T3 (sr) |
| EA (1) | EA015013B1 (sr) |
| ES (1) | ES2321651T3 (sr) |
| HK (1) | HK1118297A1 (sr) |
| HR (1) | HRP20090230T1 (sr) |
| IL (1) | IL185147A (sr) |
| MX (1) | MX2007009628A (sr) |
| PL (1) | PL1851239T3 (sr) |
| PT (1) | PT1851239E (sr) |
| RS (1) | RS50977B (sr) |
| SI (1) | SI1851239T1 (sr) |
| WO (1) | WO2006084746A1 (sr) |
| ZA (1) | ZA200707216B (sr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005006388A1 (de) | 2005-02-11 | 2006-08-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Replikationsdefiziente RNA-Viren als Impfstoffe |
| ES2937147T3 (es) | 2007-12-27 | 2023-03-24 | Univ Zuerich | Vectores arenavíricos defectuosos en la replicación |
| EP2085479A1 (en) * | 2008-01-31 | 2009-08-05 | Institut Pasteur | Reverse genetics of negative-strand rna viruses in yeast |
| WO2010134526A1 (ja) * | 2009-05-18 | 2010-11-25 | 独立行政法人産業技術総合研究所 | 多能性幹細胞作成用ベクター材料及びこれを用いた多能性幹細胞作成方法 |
| US9365866B2 (en) | 2009-06-03 | 2016-06-14 | National Institute Of Advanced Industrial Science And Technology | Vectors for generating pluripotent stem cells and methods of producing pluripotent stem cells using the same |
| DE102010018961B4 (de) * | 2010-04-23 | 2012-09-20 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Genetisch modifiziertes Paramyxovirus zur Behandlung von Tumorerkrankungen |
| US8911975B2 (en) | 2011-02-08 | 2014-12-16 | Mie University | Method for producing virus vector for gene transfer |
| US9617560B2 (en) * | 2011-10-05 | 2017-04-11 | Genvec, Inc. | Simian (gorilla) adenovirus or adenoviral vectors and methods of use |
| EP2669381A1 (en) * | 2012-05-30 | 2013-12-04 | AmVac AG | Method for expression of heterologous proteins using a recombinant negative-strand RNA virus vector comprising a mutated P protein |
| WO2014140301A1 (en) | 2013-03-15 | 2014-09-18 | Université De Genève | Anti-mycobacterial vaccines |
| EP2813574B1 (en) * | 2013-06-10 | 2019-02-20 | RSV Genius GmbH | Semi-live respiratory syncytial virus vaccine |
| EA201592298A1 (ru) * | 2013-06-10 | 2016-06-30 | Амвак Аг | Полуживая вирусная вакцина против респираторно-синцитиального вируса |
| WO2023227758A1 (en) | 2022-05-25 | 2023-11-30 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Vaccine with reduced anti-vector antigenicity |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT702085E (pt) | 1994-07-18 | 2004-04-30 | Karl Klaus Conzelmann | Virus de arn de cadeia negativa nao segmentada infeccioso recombinante |
| CA2236378C (en) | 1995-11-01 | 2011-01-25 | Dnavec Research Inc. | Recombinant sendai virus |
| JP4795597B2 (ja) | 1999-12-10 | 2011-10-19 | アメリカ合衆国 | パラインフルエンザウィルス（ｐｉｖ）及びヒトの病原体により引き起こされる感染及び疾病を保護するためへの組換えｐｉｖのベクターとしての使用 |
| JP4791651B2 (ja) * | 2000-05-18 | 2011-10-12 | 株式会社ディナベック研究所 | 外来遺伝子導入用パラミクソウイルスベクター |
| CN1633599A (zh) | 2001-09-18 | 2005-06-29 | 株式会社载体研究所 | 检查和制造降低了粒子形成能力的(－)链rna载体的方法 |
| JP2004344001A (ja) * | 2003-03-07 | 2004-12-09 | Dnavec Research Inc | 胚性幹細胞に遺伝子を導入する方法 |
| JP2004357689A (ja) * | 2003-06-03 | 2004-12-24 | Dnavec Research Inc | 遺伝子導入ベクターの非侵襲的インビボ評価方法 |
| BRPI0411247A (pt) * | 2003-06-09 | 2006-07-25 | Wyeth Corp | processo melhorado para a recuperação de vìrus de rna de filamento negativo não segmentado partindo do cdna |
| DE102005006388A1 (de) | 2005-02-11 | 2006-08-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Replikationsdefiziente RNA-Viren als Impfstoffe |
-
2005
- 2005-02-11 DE DE102005006388A patent/DE102005006388A1/de not_active Withdrawn
-
2006
- 2006-02-10 DE DE502006002711T patent/DE502006002711D1/de active Active
- 2006-02-10 MX MX2007009628A patent/MX2007009628A/es active IP Right Grant
- 2006-02-10 PL PL06706871T patent/PL1851239T3/pl unknown
- 2006-02-10 PT PT06706871T patent/PT1851239E/pt unknown
- 2006-02-10 ES ES06706871T patent/ES2321651T3/es active Active
- 2006-02-10 BR BRPI0607487-1A patent/BRPI0607487A2/pt not_active Application Discontinuation
- 2006-02-10 CN CN2006800090622A patent/CN101155826B/zh active Active
- 2006-02-10 EP EP09000617A patent/EP2045260A1/de not_active Withdrawn
- 2006-02-10 AT AT06706871T patent/ATE421529T1/de active
- 2006-02-10 EA EA200701695A patent/EA015013B1/ru not_active IP Right Cessation
- 2006-02-10 JP JP2007554510A patent/JP5679620B2/ja not_active Expired - Fee Related
- 2006-02-10 SI SI200630270T patent/SI1851239T1/sl unknown
- 2006-02-10 AU AU2006212385A patent/AU2006212385B2/en not_active Ceased
- 2006-02-10 WO PCT/EP2006/001251 patent/WO2006084746A1/de active Application Filing
- 2006-02-10 EP EP06706871A patent/EP1851239B1/de active Active
- 2006-02-10 CA CA2599036A patent/CA2599036C/en not_active Expired - Fee Related
- 2006-02-10 DK DK06706871T patent/DK1851239T3/da active
- 2006-02-10 RS RSP-2009/0185A patent/RS50977B/sr unknown
- 2006-02-10 KR KR1020077020606A patent/KR101279636B1/ko active IP Right Grant
-
2007
- 2007-08-09 IL IL185147A patent/IL185147A/en not_active IP Right Cessation
- 2007-08-09 US US11/836,322 patent/US20090041725A1/en not_active Abandoned
- 2007-08-27 ZA ZA200707216A patent/ZA200707216B/en unknown
-
2008
- 2008-08-20 HK HK08109296.4A patent/HK1118297A1/xx not_active IP Right Cessation
-
2009
- 2009-04-20 HR HR20090230T patent/HRP20090230T1/xx unknown
-
2012
- 2012-07-23 JP JP2012162993A patent/JP2012213407A/ja active Pending
-
2017
- 2017-05-25 US US15/605,568 patent/US11028409B2/en active Active
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