RS50977B - Replikaciono defektni rnk-virusi kao vakcine - Google Patents

Replikaciono defektni rnk-virusi kao vakcine

Info

Publication number
RS50977B
RS50977B RSP-2009/0185A RSP20090185A RS50977B RS 50977 B RS50977 B RS 50977B RS P20090185 A RSP20090185 A RS P20090185A RS 50977 B RS50977 B RS 50977B
Authority
RS
Serbia
Prior art keywords
replication
vaccines
rna viruses
deficient rna
loss
Prior art date
Application number
RSP-2009/0185A
Other languages
English (en)
Inventor
Wolfgang J. Neubert
Sascha Bossow
Sabine Schlecht
Original Assignee
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. filed Critical MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.
Publication of RS50977B publication Critical patent/RS50977B/sr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Rekombinantni negativni lanac RNK-virusa koji sadrži virusni genom sa mutacijom u genu P, koja dovodi do gubljenja sposobnosti replikacije bez gubljenja sekundarne sposobnosti transkripcije.Prijava sadrži još 36 patentnih zahteva.
RSP-2009/0185A 2005-02-11 2006-02-10 Replikaciono defektni rnk-virusi kao vakcine RS50977B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005006388A DE102005006388A1 (de) 2005-02-11 2005-02-11 Replikationsdefiziente RNA-Viren als Impfstoffe
PCT/EP2006/001251 WO2006084746A1 (de) 2005-02-11 2006-02-10 Replikationsdefiziente rna-viren als impfstoffe

Publications (1)

Publication Number Publication Date
RS50977B true RS50977B (sr) 2010-10-31

Family

ID=36353666

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2009/0185A RS50977B (sr) 2005-02-11 2006-02-10 Replikaciono defektni rnk-virusi kao vakcine

Country Status (23)

Country Link
US (2) US20090041725A1 (sr)
EP (2) EP1851239B1 (sr)
JP (2) JP5679620B2 (sr)
KR (1) KR101279636B1 (sr)
CN (1) CN101155826B (sr)
AT (1) ATE421529T1 (sr)
AU (1) AU2006212385B2 (sr)
BR (1) BRPI0607487A2 (sr)
CA (1) CA2599036C (sr)
DE (2) DE102005006388A1 (sr)
DK (1) DK1851239T3 (sr)
EA (1) EA015013B1 (sr)
ES (1) ES2321651T3 (sr)
HK (1) HK1118297A1 (sr)
HR (1) HRP20090230T1 (sr)
IL (1) IL185147A (sr)
MX (1) MX2007009628A (sr)
PL (1) PL1851239T3 (sr)
PT (1) PT1851239E (sr)
RS (1) RS50977B (sr)
SI (1) SI1851239T1 (sr)
WO (1) WO2006084746A1 (sr)
ZA (1) ZA200707216B (sr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005006388A1 (de) 2005-02-11 2006-08-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Replikationsdefiziente RNA-Viren als Impfstoffe
HRP20221475T3 (hr) 2007-12-27 2023-01-06 Universität Zürich Replikacijski defektni vektori arenavirusa
EP2085479A1 (en) * 2008-01-31 2009-08-05 Institut Pasteur Reverse genetics of negative-strand rna viruses in yeast
JP5633075B2 (ja) * 2009-05-18 2014-12-03 独立行政法人産業技術総合研究所 多能性幹細胞作成用ベクター材料及びこれを用いた多能性幹細胞作成方法
US9365866B2 (en) 2009-06-03 2016-06-14 National Institute Of Advanced Industrial Science And Technology Vectors for generating pluripotent stem cells and methods of producing pluripotent stem cells using the same
DE102010018961B4 (de) * 2010-04-23 2012-09-20 Eberhard-Karls-Universität Tübingen Universitätsklinikum Genetisch modifiziertes Paramyxovirus zur Behandlung von Tumorerkrankungen
ES2640113T3 (es) 2011-02-08 2017-10-31 Mie University Método para producir un vector viral para la transferencia génica
JP6757121B2 (ja) * 2011-10-05 2020-09-16 ジェンヴェック エルエルシー シミアン（ゴリラ）アデノウイルス又はアデノウイルスベクター、及び使用方法
EP2669381A1 (en) * 2012-05-30 2013-12-04 AmVac AG Method for expression of heterologous proteins using a recombinant negative-strand RNA virus vector comprising a mutated P protein
EP2968506B1 (en) 2013-03-15 2019-07-31 Université de Genève Anti-mycobacterial vaccines
EP2813574B1 (en) * 2013-06-10 2019-02-20 RSV Genius GmbH Semi-live respiratory syncytial virus vaccine
WO2014198407A1 (en) * 2013-06-10 2014-12-18 Amvac Ag Semi-live respiratory syncytial virus vaccine
WO2023227758A1 (en) 2022-05-25 2023-11-30 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccine with reduced anti-vector antigenicity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0702085T4 (da) 1994-07-18 2010-04-06 Conzelmann Karl Klaus Prof Dr Rekombinant infektiøs ikke-segmenteret negativ-strenget RNA-virus
WO1997016539A1 (fr) * 1995-11-01 1997-05-09 Dnavec Research Inc. Virus sendai recombinant
AU785148B2 (en) 1999-12-10 2006-10-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Use of recombinant parainfluenza viruses (PIVs) as vectors to protect against infection and disease caused by PIV and other human pathogens
JP4791651B2 (ja) * 2000-05-18 2011-10-12 株式会社ディナベック研究所 外来遺伝子導入用パラミクソウイルスベクター
KR20040039366A (ko) * 2001-09-18 2004-05-10 가부시키가이샤 디나벡크 겐큐쇼 입자 형성능이 저하된 （－）가닥 ｒｎａ 바이러스 벡터의 검사방법 및 제조방법
JP2004344001A (ja) * 2003-03-07 2004-12-09 Dnavec Research Inc 胚性幹細胞に遺伝子を導入する方法
JP2004357689A (ja) * 2003-06-03 2004-12-24 Dnavec Research Inc 遺伝子導入ベクターの非侵襲的インビボ評価方法
KR101020532B1 (ko) * 2003-06-09 2011-03-09 와이어쓰 엘엘씨 ｃＤＮＡ로부터의 비분절 네가티브 쇄 ＲＮＡ 바이러스의 회수를 위한 개선된 방법
DE102005006388A1 (de) 2005-02-11 2006-08-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Replikationsdefiziente RNA-Viren als Impfstoffe

Also Published As

Publication number Publication date
EA015013B1 (ru) 2011-04-29
EP1851239B1 (de) 2009-01-21
ES2321651T3 (es) 2009-06-09
IL185147A (en) 2011-12-29
EP1851239A1 (de) 2007-11-07
KR101279636B1 (ko) 2013-06-28
KR20070110345A (ko) 2007-11-16
MX2007009628A (es) 2007-11-15
CN101155826B (zh) 2011-10-12
DE102005006388A1 (de) 2006-08-24
JP2008529508A (ja) 2008-08-07
EA200701695A1 (ru) 2008-02-28
PL1851239T3 (pl) 2009-07-31
CN101155826A (zh) 2008-04-02
JP5679620B2 (ja) 2015-03-04
HK1118297A1 (en) 2009-02-06
EP2045260A1 (de) 2009-04-08
DK1851239T3 (da) 2009-05-18
DE502006002711D1 (de) 2009-03-12
CA2599036C (en) 2014-11-04
AU2006212385A1 (en) 2006-08-17
ATE421529T1 (de) 2009-02-15
US11028409B2 (en) 2021-06-08
JP2012213407A (ja) 2012-11-08
ZA200707216B (en) 2008-05-28
AU2006212385B2 (en) 2011-12-15
WO2006084746A1 (de) 2006-08-17
PT1851239E (pt) 2009-04-28
HRP20090230T1 (en) 2009-05-31
US20090041725A1 (en) 2009-02-12
IL185147A0 (en) 2007-12-03
US20180142256A1 (en) 2018-05-24
CA2599036A1 (en) 2006-08-17
BRPI0607487A2 (pt) 2009-09-08
SI1851239T1 (sl) 2009-08-31

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