RS50821B - Derivati pirazolopiridina kao inhibitori beta-adrenergičnog receptora kinaze 1 - Google Patents

Derivati pirazolopiridina kao inhibitori beta-adrenergičnog receptora kinaze 1

Info

Publication number
RS50821B
RS50821B RSP-2009/0165A RSP20090165A RS50821B RS 50821 B RS50821 B RS 50821B RS P20090165 A RSP20090165 A RS P20090165A RS 50821 B RS50821 B RS 50821B
Authority
RS
Serbia
Prior art keywords
alkyl
alkylene
group
heterocyclyl
aryl
Prior art date
Application number
RSP-2009/0165A
Other languages
English (en)
Inventor
Henning Steinhagen
Jochen Huber
Kurt Ritter
Bernard Pirard
Kirsten Bjergarde
Marcel Patek
Martin Smrcina
Linli Wei
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of RS50821B publication Critical patent/RS50821B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RSP-2009/0165A 2005-06-27 2006-06-13 Derivati pirazolopiridina kao inhibitori beta-adrenergičnog receptora kinaze 1 RS50821B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05013774 2005-06-27
PCT/EP2006/005649 WO2007000241A1 (en) 2005-06-27 2006-06-13 Pyrazolopyridine derivatives as inhibitors of beta-adrenergic receptor kinase 1

Publications (1)

Publication Number Publication Date
RS50821B true RS50821B (sr) 2010-08-31

Family

ID=35395578

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2009/0165A RS50821B (sr) 2005-06-27 2006-06-13 Derivati pirazolopiridina kao inhibitori beta-adrenergičnog receptora kinaze 1

Country Status (30)

Country Link
US (1) US7910602B2 (sr)
EP (1) EP1899333B1 (sr)
JP (1) JP5010594B2 (sr)
KR (1) KR20080020638A (sr)
CN (1) CN101208340B (sr)
AR (1) AR054514A1 (sr)
AT (1) ATE423118T1 (sr)
AU (1) AU2006264044A1 (sr)
BR (1) BRPI0612320A2 (sr)
CA (1) CA2611296A1 (sr)
CY (1) CY1110464T1 (sr)
DE (1) DE602006005242D1 (sr)
DK (1) DK1899333T3 (sr)
ES (1) ES2322197T3 (sr)
HR (1) HRP20090244T2 (sr)
IL (1) IL188381A0 (sr)
MA (1) MA29498B1 (sr)
MX (1) MX2007015829A (sr)
MY (1) MY139016A (sr)
NO (1) NO20080392L (sr)
NZ (1) NZ564757A (sr)
PL (1) PL1899333T3 (sr)
PT (1) PT1899333E (sr)
RS (1) RS50821B (sr)
RU (1) RU2415855C2 (sr)
SI (1) SI1899333T1 (sr)
TW (1) TW200800982A (sr)
UY (1) UY29632A1 (sr)
WO (1) WO2007000241A1 (sr)
ZA (1) ZA200709853B (sr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
JPWO2009107391A1 (ja) * 2008-02-27 2011-06-30 武田薬品工業株式会社 ６員芳香環含有化合物
US9321787B2 (en) * 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
US9394285B2 (en) 2013-03-15 2016-07-19 Pfizer Inc. Indole and indazole compounds that activate AMPK
GB201410815D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents
JP2022505707A (ja) * 2018-10-24 2022-01-14 ブリストル－マイヤーズ スクイブ カンパニー 置換インドールおよびインダゾール化合物
CN112912382B (zh) 2018-10-24 2024-07-02 百时美施贵宝公司 经取代的吲哚二聚体化合物
WO2024137671A1 (en) * 2022-12-20 2024-06-27 Exelixis, Inc. Compounds that inhibit pkmyt1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043998B1 (en) * 1997-12-13 2007-03-07 Bristol-Myers Squibb Company USE OF PYRAZOLO [3,4-b] PYRIDINE AS CYCLIN DEPENDANT KINASE INHIBITORS
JP2002020386A (ja) * 2000-07-07 2002-01-23 Ono Pharmaceut Co Ltd ピラゾロピリジン誘導体
WO2003068773A1 (en) * 2002-02-12 2003-08-21 Glaxo Group Limited Pyrazolopyridine derivatives
EP1537106A1 (en) * 2002-08-07 2005-06-08 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds
JP4814783B2 (ja) * 2003-02-27 2011-11-16 パラウ ファルマ、 ソシエダッド アノニマ ピラゾロピリジン誘導体

Also Published As

Publication number Publication date
EP1899333B1 (en) 2009-02-18
TW200800982A (en) 2008-01-01
RU2008102970A (ru) 2009-08-10
US7910602B2 (en) 2011-03-22
HRP20090244T2 (en) 2009-07-31
ZA200709853B (en) 2008-12-31
PT1899333E (pt) 2009-04-23
NO20080392L (no) 2008-02-28
RU2415855C2 (ru) 2011-04-10
JP5010594B2 (ja) 2012-08-29
MY139016A (en) 2009-08-28
ATE423118T1 (de) 2009-03-15
HRP20090244T1 (en) 2009-06-30
DE602006005242D1 (de) 2009-04-02
JP2008543957A (ja) 2008-12-04
AU2006264044A1 (en) 2007-01-04
UY29632A1 (es) 2007-01-31
BRPI0612320A2 (pt) 2010-11-09
AR054514A1 (es) 2007-06-27
CA2611296A1 (en) 2007-01-04
IL188381A0 (en) 2008-04-13
MA29498B1 (fr) 2008-05-02
CY1110464T1 (el) 2015-04-29
CN101208340A (zh) 2008-06-25
PL1899333T3 (pl) 2009-07-31
KR20080020638A (ko) 2008-03-05
DK1899333T3 (da) 2009-06-15
NZ564757A (en) 2009-12-24
WO2007000241A1 (en) 2007-01-04
US20080227777A1 (en) 2008-09-18
CN101208340B (zh) 2010-12-22
SI1899333T1 (sl) 2009-08-31
MX2007015829A (es) 2008-02-22
ES2322197T3 (es) 2009-06-17
EP1899333A1 (en) 2008-03-19

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