RS20080141A - Inhibitors of the hiv integrase enzyme - Google Patents
Inhibitors of the hiv integrase enzymeInfo
- Publication number
- RS20080141A RS20080141A RSP-2008/0141A RSP20080141A RS20080141A RS 20080141 A RS20080141 A RS 20080141A RS P20080141 A RSP20080141 A RS P20080141A RS 20080141 A RS20080141 A RS 20080141A
- Authority
- RS
- Serbia
- Prior art keywords
- inhibitors
- integrase enzyme
- hiv integrase
- hiv
- enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Abstract
Ovaj pronalazak se odnosi na jedinjenja formule (I), i njihove farmaceutski prihvatljive soli i solvate, na njihovu sintezu i na njihovu upotrebu kao modulatora ili inhibitora enzima integraze humanog virusa imunodeficitarnosti ("HIV").
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72448405P | 2005-10-07 | 2005-10-07 | |
US73070105P | 2005-10-26 | 2005-10-26 | |
US76160506P | 2006-01-24 | 2006-01-24 | |
US82395406P | 2006-08-30 | 2006-08-30 | |
US82637906P | 2006-09-20 | 2006-09-20 | |
PCT/IB2006/002735 WO2007042883A1 (en) | 2005-10-07 | 2006-09-25 | Inhibitors of the hiv integrase enzyme |
Publications (1)
Publication Number | Publication Date |
---|---|
RS20080141A true RS20080141A (en) | 2009-07-15 |
Family
ID=37684843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RSP-2008/0141A RS20080141A (en) | 2005-10-07 | 2006-09-25 | Inhibitors of the hiv integrase enzyme |
Country Status (21)
Country | Link |
---|---|
US (1) | US20070099915A1 (sr) |
EP (1) | EP1934220A1 (sr) |
JP (1) | JP2009511463A (sr) |
KR (1) | KR20080042171A (sr) |
AP (1) | AP2008004400A0 (sr) |
AR (1) | AR061398A1 (sr) |
AU (1) | AU2006300926A1 (sr) |
BR (1) | BRPI0616657A2 (sr) |
CA (1) | CA2623506A1 (sr) |
CR (1) | CR9859A (sr) |
EA (1) | EA200800758A1 (sr) |
IL (1) | IL189939A0 (sr) |
MA (1) | MA29855B1 (sr) |
NL (1) | NL2000255A1 (sr) |
NO (1) | NO20081230L (sr) |
PE (1) | PE20070494A1 (sr) |
RS (1) | RS20080141A (sr) |
SV (1) | SV2009002864A (sr) |
TW (1) | TW200800219A (sr) |
UY (1) | UY29843A1 (sr) |
WO (1) | WO2007042883A1 (sr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007534738A (ja) * | 2004-04-26 | 2007-11-29 | ファイザー・インク | Hivインテグラーゼ酵素の阻害剤 |
EP2234608A2 (en) | 2007-12-11 | 2010-10-06 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
CN102532021B (zh) * | 2012-01-31 | 2013-10-16 | 天津大学 | 2-烷氧基-3,4-二取代异喹啉-1(2h)-酮类衍生物的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
US5616609A (en) * | 1991-08-08 | 1997-04-01 | Ikekawa; Tetsuro | Carcinostatic compound and production thereof |
US5726203A (en) * | 1993-07-19 | 1998-03-10 | Li; Zelin | Qinghaosu derivatives against AIDS |
US6057297A (en) * | 1996-08-06 | 2000-05-02 | Polifarma S.P.A. | Inhibitor compounds of zinc-dependent metalloproteinases associated with pathological conditions, and therapeutic use thereof |
FR2754262B1 (fr) * | 1996-10-08 | 1998-10-30 | Synthelabo | Derives de 1h-pyrido[3,4-b]indole-4-carboxamide, leur preparation et leur application en therapeutique |
US6403347B1 (en) * | 1998-02-03 | 2002-06-11 | Merck & Co., Inc. | HIV integrase inhibitors |
AU8009900A (en) * | 1999-10-13 | 2001-04-23 | Merck & Co., Inc. | Hiv integrase inhibitors |
CN1239472C (zh) * | 2000-06-16 | 2006-02-01 | 布里斯托尔-迈尔斯斯奎布公司 | Hiv整合酶抑制剂 |
PA8586801A1 (es) * | 2002-10-31 | 2005-02-04 | Pfizer | Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso |
BRPI0407052A (pt) * | 2003-01-27 | 2006-01-17 | Pfizer | Inibidores da hiv-integrase, composições farmacêuticas, e métodos para sua utilização |
JP2007534738A (ja) * | 2004-04-26 | 2007-11-29 | ファイザー・インク | Hivインテグラーゼ酵素の阻害剤 |
BRPI0514724A (pt) * | 2004-09-07 | 2008-06-24 | Pfizer | inibidores da enzima hiv integrase |
-
2006
- 2006-09-25 EP EP06808923A patent/EP1934220A1/en not_active Withdrawn
- 2006-09-25 EA EA200800758A patent/EA200800758A1/ru unknown
- 2006-09-25 CA CA002623506A patent/CA2623506A1/en not_active Abandoned
- 2006-09-25 AU AU2006300926A patent/AU2006300926A1/en not_active Abandoned
- 2006-09-25 KR KR1020087008162A patent/KR20080042171A/ko not_active Application Discontinuation
- 2006-09-25 JP JP2008534098A patent/JP2009511463A/ja not_active Withdrawn
- 2006-09-25 BR BRPI0616657-1A patent/BRPI0616657A2/pt not_active Application Discontinuation
- 2006-09-25 RS RSP-2008/0141A patent/RS20080141A/sr unknown
- 2006-09-25 WO PCT/IB2006/002735 patent/WO2007042883A1/en active Application Filing
- 2006-09-25 AP AP2008004400A patent/AP2008004400A0/xx unknown
- 2006-10-03 NL NL2000255A patent/NL2000255A1/nl active Search and Examination
- 2006-10-04 AR ARP060104374A patent/AR061398A1/es not_active Application Discontinuation
- 2006-10-05 PE PE2006001216A patent/PE20070494A1/es not_active Application Discontinuation
- 2006-10-05 TW TW095137139A patent/TW200800219A/zh unknown
- 2006-10-06 UY UY29843A patent/UY29843A1/es not_active Application Discontinuation
- 2006-10-06 US US11/539,205 patent/US20070099915A1/en not_active Abandoned
-
2008
- 2008-02-04 CR CR9859A patent/CR9859A/es not_active Application Discontinuation
- 2008-03-04 IL IL189939A patent/IL189939A0/en unknown
- 2008-03-07 NO NO20081230A patent/NO20081230L/no not_active Application Discontinuation
- 2008-04-07 SV SV2008002864A patent/SV2009002864A/es not_active Application Discontinuation
- 2008-04-07 MA MA30821A patent/MA29855B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
KR20080042171A (ko) | 2008-05-14 |
US20070099915A1 (en) | 2007-05-03 |
NO20081230L (no) | 2008-04-08 |
TW200800219A (en) | 2008-01-01 |
SV2009002864A (es) | 2009-02-19 |
JP2009511463A (ja) | 2009-03-19 |
UY29843A1 (es) | 2007-05-31 |
WO2007042883A1 (en) | 2007-04-19 |
IL189939A0 (en) | 2008-08-07 |
EA200800758A1 (ru) | 2008-08-29 |
AP2008004400A0 (en) | 2008-04-30 |
PE20070494A1 (es) | 2007-06-13 |
NL2000255A1 (nl) | 2007-04-11 |
AR061398A1 (es) | 2008-08-27 |
CR9859A (es) | 2008-06-20 |
EP1934220A1 (en) | 2008-06-25 |
MA29855B1 (fr) | 2008-10-03 |
CA2623506A1 (en) | 2007-04-19 |
AU2006300926A1 (en) | 2007-04-19 |
BRPI0616657A2 (pt) | 2011-06-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2005103003A3 (en) | Pyrrolopyridine derivatives and their use as hiv-integrase inhibitors | |
MX2007005694A (es) | Nuevos derivados de betulina, preparacion y uso de los mismos. | |
MY146669A (en) | Pyrazole derivatives for treating hiv | |
PT1940839E (pt) | Inibidores de piridopirimidinona pi3k alfa | |
EA200700099A1 (ru) | Производные пиридина | |
AP2003002915A0 (en) | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis. | |
TW200621737A (en) | 2-carbamide-4-phenylthiazole derivatives, preparation thereof and therapeutic use thereof | |
EA200702498A1 (ru) | N-(пиридин-2-ил)сульфонамидные производные | |
DE60204674D1 (de) | Retinoid x rezeptormodulatoren | |
EA200801011A1 (ru) | Производные пиразина как модуляторы натриевых каналов для лечения боли | |
WO2004096128A3 (en) | Hiv integrase inhibitors | |
MXPA05012247A (es) | Derivados de bencimidazol nuevos. | |
EA200601194A1 (ru) | Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором | |
BRPI0607214A2 (pt) | derivados de 2-(4-cianofenilamino) pirimidina inibidores de hiv | |
TW200628153A (en) | Novel compounds | |
DE60318874D1 (en) | Pyrazolderivate | |
MXPA05009282A (es) | Derivados de anilina sustituidos. | |
ATE374775T1 (de) | Inhibitoren des hiv-integrase-enzyms | |
RS20080141A (en) | Inhibitors of the hiv integrase enzyme | |
MXPA05006889A (es) | Compuestos aromaticos como agentes anti-inflamatorios, inmunomoduladores y anti-proliferativos. | |
SG171472A1 (en) | Substituted aniline derivatives | |
SE0403118D0 (sv) | New compounds 2 | |
PL1651596T3 (pl) | Nowe pochodne 4,4’ - ditiobis(3-aminobutano-1-sulfonianów) i zawierające je kompozycje | |
BR0314759A (pt) | Derivados de pirazol | |
TNSN08154A1 (fr) | Inhibiteurs de l'enzyme integrase du vih |