MA29855B1 - Inhibiteurs de l'enzyme integrase du vih - Google Patents
Inhibiteurs de l'enzyme integrase du vihInfo
- Publication number
- MA29855B1 MA29855B1 MA30821A MA30821A MA29855B1 MA 29855 B1 MA29855 B1 MA 29855B1 MA 30821 A MA30821 A MA 30821A MA 30821 A MA30821 A MA 30821A MA 29855 B1 MA29855 B1 MA 29855B1
- Authority
- MA
- Morocco
- Prior art keywords
- inhibitors
- hiv integrase
- integrase enzyme
- hiv
- enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Inhibiteurs de l'enzyme intégrase du VIH La présente invention concerne des composés de formule (I) et leurs sels et produits de solvatation pharmaceutiquement acceptables, leur synthèse et leur utilisation comme modulateurs ou inhibiteurs de l'enzyme consistant en intégrase du virus d'immunodéficience humaine ("VIH").
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72448405P | 2005-10-07 | 2005-10-07 | |
US73070105P | 2005-10-26 | 2005-10-26 | |
US76160506P | 2006-01-24 | 2006-01-24 | |
US82395406P | 2006-08-30 | 2006-08-30 | |
US82637906P | 2006-09-20 | 2006-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29855B1 true MA29855B1 (fr) | 2008-10-03 |
Family
ID=37684843
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30821A MA29855B1 (fr) | 2005-10-07 | 2008-04-07 | Inhibiteurs de l'enzyme integrase du vih |
Country Status (21)
Country | Link |
---|---|
US (1) | US20070099915A1 (fr) |
EP (1) | EP1934220A1 (fr) |
JP (1) | JP2009511463A (fr) |
KR (1) | KR20080042171A (fr) |
AP (1) | AP2008004400A0 (fr) |
AR (1) | AR061398A1 (fr) |
AU (1) | AU2006300926A1 (fr) |
BR (1) | BRPI0616657A2 (fr) |
CA (1) | CA2623506A1 (fr) |
CR (1) | CR9859A (fr) |
EA (1) | EA200800758A1 (fr) |
IL (1) | IL189939A0 (fr) |
MA (1) | MA29855B1 (fr) |
NL (1) | NL2000255A1 (fr) |
NO (1) | NO20081230L (fr) |
PE (1) | PE20070494A1 (fr) |
RS (1) | RS20080141A (fr) |
SV (1) | SV2009002864A (fr) |
TW (1) | TW200800219A (fr) |
UY (1) | UY29843A1 (fr) |
WO (1) | WO2007042883A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1751157B1 (fr) * | 2004-04-26 | 2007-10-03 | Pfizer Inc. | Inhibiteurs de l'enzyme integrase du vih |
CA2708281A1 (fr) | 2007-12-11 | 2009-08-27 | Viamet Pharmaceuticals, Inc. | Inhibiteurs de metalloenzymes utilisant des fractions de liaison a un metal en combinaison avec des fractions de ciblage |
CN102532021B (zh) * | 2012-01-31 | 2013-10-16 | 天津大学 | 2-烷氧基-3,4-二取代异喹啉-1(2h)-酮类衍生物的制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
CA2114728A1 (fr) * | 1991-08-08 | 1993-02-18 | Tetsuro Ikekawa | Compose carcinostatique et sa production |
WO1995003311A1 (fr) * | 1993-07-19 | 1995-02-02 | Xuande Luo | Derives de qinghaosu utilises pour lutter contre le sida |
US6057297A (en) * | 1996-08-06 | 2000-05-02 | Polifarma S.P.A. | Inhibitor compounds of zinc-dependent metalloproteinases associated with pathological conditions, and therapeutic use thereof |
FR2754262B1 (fr) * | 1996-10-08 | 1998-10-30 | Synthelabo | Derives de 1h-pyrido[3,4-b]indole-4-carboxamide, leur preparation et leur application en therapeutique |
US6403347B1 (en) * | 1998-02-03 | 2002-06-11 | Merck & Co., Inc. | HIV integrase inhibitors |
WO2001027309A1 (fr) * | 1999-10-13 | 2001-04-19 | Merck & Co., Inc. | Inhibiteurs d'integrase de vih |
JP2004503523A (ja) * | 2000-06-16 | 2004-02-05 | ブリストルーマイヤーズ スクイブ カンパニー | Hivインテグラーゼ阻害剤 |
PA8586801A1 (es) * | 2002-10-31 | 2005-02-04 | Pfizer | Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso |
MXPA05007563A (es) * | 2003-01-27 | 2005-09-21 | Pfizer | Inhibidores de la integrasa del vih, composiciones farmaceuticas y metodos para su uso. |
EP1751157B1 (fr) * | 2004-04-26 | 2007-10-03 | Pfizer Inc. | Inhibiteurs de l'enzyme integrase du vih |
CA2578841A1 (fr) * | 2004-09-07 | 2006-03-16 | Pfizer Inc. | Inhibiteurs de l'enzyme integrase du vih |
-
2006
- 2006-09-25 AP AP2008004400A patent/AP2008004400A0/xx unknown
- 2006-09-25 EP EP06808923A patent/EP1934220A1/fr not_active Withdrawn
- 2006-09-25 JP JP2008534098A patent/JP2009511463A/ja not_active Withdrawn
- 2006-09-25 BR BRPI0616657-1A patent/BRPI0616657A2/pt not_active Application Discontinuation
- 2006-09-25 AU AU2006300926A patent/AU2006300926A1/en not_active Abandoned
- 2006-09-25 WO PCT/IB2006/002735 patent/WO2007042883A1/fr active Application Filing
- 2006-09-25 RS RSP-2008/0141A patent/RS20080141A/sr unknown
- 2006-09-25 KR KR1020087008162A patent/KR20080042171A/ko not_active Application Discontinuation
- 2006-09-25 EA EA200800758A patent/EA200800758A1/ru unknown
- 2006-09-25 CA CA002623506A patent/CA2623506A1/fr not_active Abandoned
- 2006-10-03 NL NL2000255A patent/NL2000255A1/nl active Search and Examination
- 2006-10-04 AR ARP060104374A patent/AR061398A1/es not_active Application Discontinuation
- 2006-10-05 PE PE2006001216A patent/PE20070494A1/es not_active Application Discontinuation
- 2006-10-05 TW TW095137139A patent/TW200800219A/zh unknown
- 2006-10-06 US US11/539,205 patent/US20070099915A1/en not_active Abandoned
- 2006-10-06 UY UY29843A patent/UY29843A1/es not_active Application Discontinuation
-
2008
- 2008-02-04 CR CR9859A patent/CR9859A/es not_active Application Discontinuation
- 2008-03-04 IL IL189939A patent/IL189939A0/en unknown
- 2008-03-07 NO NO20081230A patent/NO20081230L/no not_active Application Discontinuation
- 2008-04-07 SV SV2008002864A patent/SV2009002864A/es not_active Application Discontinuation
- 2008-04-07 MA MA30821A patent/MA29855B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US20070099915A1 (en) | 2007-05-03 |
EP1934220A1 (fr) | 2008-06-25 |
NO20081230L (no) | 2008-04-08 |
BRPI0616657A2 (pt) | 2011-06-28 |
AR061398A1 (es) | 2008-08-27 |
AU2006300926A1 (en) | 2007-04-19 |
AP2008004400A0 (en) | 2008-04-30 |
CR9859A (es) | 2008-06-20 |
TW200800219A (en) | 2008-01-01 |
UY29843A1 (es) | 2007-05-31 |
CA2623506A1 (fr) | 2007-04-19 |
KR20080042171A (ko) | 2008-05-14 |
WO2007042883A1 (fr) | 2007-04-19 |
EA200800758A1 (ru) | 2008-08-29 |
RS20080141A (en) | 2009-07-15 |
JP2009511463A (ja) | 2009-03-19 |
PE20070494A1 (es) | 2007-06-13 |
IL189939A0 (en) | 2008-08-07 |
SV2009002864A (es) | 2009-02-19 |
NL2000255A1 (nl) | 2007-04-11 |
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