RS20050528A - Pyridine derivatives useful for inhibiting sodium/calcium exchange system - Google Patents
Pyridine derivatives useful for inhibiting sodium/calcium exchange systemInfo
- Publication number
- RS20050528A RS20050528A YUP-2005/0528A YUP20050528A RS20050528A RS 20050528 A RS20050528 A RS 20050528A YU P20050528 A YUP20050528 A YU P20050528A RS 20050528 A RS20050528 A RS 20050528A
- Authority
- RS
- Serbia
- Prior art keywords
- formula
- halogen
- case
- nhc
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20030030A FI20030030A0 (fi) | 2003-01-09 | 2003-01-09 | Uusia yhdisteitä |
| PCT/FI2004/000011 WO2004063191A1 (en) | 2003-01-09 | 2004-01-09 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS20050528A true RS20050528A (en) | 2007-06-04 |
Family
ID=8565286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-2005/0528A RS20050528A (en) | 2003-01-09 | 2004-01-09 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7482340B2 (sr) |
| EP (1) | EP1583759A1 (sr) |
| JP (1) | JP2006516271A (sr) |
| KR (1) | KR20050095601A (sr) |
| CN (1) | CN100457752C (sr) |
| AR (1) | AR042733A1 (sr) |
| AU (1) | AU2004203943B2 (sr) |
| BR (1) | BRPI0406669A (sr) |
| CA (1) | CA2512184A1 (sr) |
| EA (1) | EA008539B1 (sr) |
| FI (1) | FI20030030A0 (sr) |
| HR (1) | HRP20050703A2 (sr) |
| IL (1) | IL169435A0 (sr) |
| IS (1) | IS7969A (sr) |
| MX (1) | MXPA05007435A (sr) |
| NO (1) | NO20053730L (sr) |
| NZ (1) | NZ541087A (sr) |
| PL (1) | PL378326A1 (sr) |
| RS (1) | RS20050528A (sr) |
| UA (1) | UA81941C2 (sr) |
| WO (1) | WO2004063191A1 (sr) |
| ZA (1) | ZA200505461B (sr) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20011507A0 (fi) * | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
| KR101233223B1 (ko) * | 2004-12-21 | 2013-02-14 | 제이엔씨 석유 화학 주식회사 | 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자 |
| UA109896C2 (xx) * | 2007-02-22 | 2015-10-26 | Похідні імінопіридину та їх застосування як мікробіоцидів | |
| EP2649066B1 (en) * | 2010-12-06 | 2015-10-21 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
| EP2524908A1 (en) * | 2011-05-20 | 2012-11-21 | LEK Pharmaceuticals d.d. | Process for the preparation of alfa-substituted ketones and their application in synthesis of pharmaceutically active compounds |
| SI2567958T1 (sl) | 2011-09-12 | 2015-01-30 | Sanofi | Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki |
| WO2013037388A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
| JP5941637B2 (ja) * | 2011-09-12 | 2016-06-29 | サノフイ | 置換２−（クロマン−６−イルオキシ）−チアゾール及び医薬としてのその使用 |
| US8912224B2 (en) | 2011-09-12 | 2014-12-16 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
| WO2013144191A1 (de) * | 2012-03-29 | 2013-10-03 | Bayer Intellectual Property Gmbh | Substituierte 2 -amino - 3 - cyanopyridine als inhibitoren des natrium calcium austausches und ihre verwendung bei kardiovaskulären erkrankungen |
| TWI633095B (zh) * | 2013-03-08 | 2018-08-21 | 賽諾菲公司 | 經取代－６－基氧基－環烷類及其作為醫藥品之用途 |
| GB201416186D0 (en) | 2014-09-12 | 2014-10-29 | Redx Pharma Ltd | Compounds |
| EP3265445B1 (en) | 2015-03-06 | 2021-05-05 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| MX2017011269A (es) | 2015-03-06 | 2018-01-12 | Pharmakea Inc | Inhibidores de lisil oxidasa tipo 2 fluorinados y usos de los mismos. |
| CN108137807B (zh) * | 2015-08-19 | 2020-09-29 | 日产化学工业株式会社 | 液晶取向剂中使用的酰亚胺系聚合物 |
| EP4385571A2 (en) | 2016-09-07 | 2024-06-19 | Pharmakea, Inc. | Uses of a lysyl oxidase-like 2 inhibitor related applications |
| KR102587178B1 (ko) | 2016-09-07 | 2023-10-06 | 파마케아, 인크. | 리실 옥시다아제-유사 2 억제제의 결정질 형태 및 제조 방법 |
| WO2019175464A1 (en) | 2018-03-14 | 2019-09-19 | Orion Corporation | Compounds useful as inhibitors of sodium-calcium exchanger (ncx) |
| IL300113A (en) | 2020-07-28 | 2023-03-01 | Jazz Pharmaceuticals Ireland Ltd | Compressed cyclic RAF inhibitors and methods of using them |
| CN115850258A (zh) * | 2022-12-27 | 2023-03-28 | 东北林业大学 | 一种马赛替尼的合成方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2820817A (en) * | 1954-02-04 | 1958-01-21 | Mcneilab Inc | Oxygenated indan compounds and method of making the same |
| BE650081A (sr) | 1963-07-03 | |||
| US3862232A (en) * | 1963-07-03 | 1975-01-21 | Upjohn Co | 1-(p-hydroxyphenyl)-2-phenyl-6-(2-diethylaminoethoxy)-3,4-dihydronaphthalene and the salts thereof |
| GB1154119A (en) | 1968-05-20 | 1969-06-04 | Merck Ag E | 3-Alkyl-Flavanones |
| JPH04113839A (ja) * | 1990-09-05 | 1992-04-15 | Mitsubishi Petrochem Co Ltd | ポリカーボネート樹脂積層物 |
| FR2733685B1 (fr) * | 1995-05-05 | 1997-05-30 | Adir | Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant |
| JPH0967336A (ja) | 1995-09-04 | 1997-03-11 | Kanebo Ltd | 新規なイソチオウレア誘導体 |
| WO1998043943A1 (fr) | 1997-03-27 | 1998-10-08 | Taisho Pharmaceutical Co., Ltd. | Derives de 2-phenoxyaniline |
| JPH1149752A (ja) * | 1997-08-05 | 1999-02-23 | Taisho Pharmaceut Co Ltd | フェノキシピリジン誘導体 |
| DE19742508A1 (de) * | 1997-09-26 | 1999-04-01 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen |
| DK1031556T3 (da) | 1997-10-20 | 2003-02-24 | Taisho Pharmaceutical Co Ltd | 2-phenoxyanilinderivater |
| JPH11302235A (ja) | 1998-04-15 | 1999-11-02 | Taisho Pharmaceut Co Ltd | フェノキシアルキルアミン誘導体 |
| AU4360200A (en) | 1999-04-23 | 2000-11-10 | Bristol-Myers Squibb Company | Bicyclic acyl guanidine sodium/proton exchange inhibitors and method |
| CZ2002802A3 (cs) * | 1999-09-17 | 2003-02-12 | Nissan Chemical Industries, Ltd. | Benzopyranové deriváty |
| FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
-
2003
- 2003-01-09 FI FI20030030A patent/FI20030030A0/fi unknown
-
2004
- 2004-01-08 AR ARP040100052A patent/AR042733A1/es unknown
- 2004-01-09 WO PCT/FI2004/000011 patent/WO2004063191A1/en active Application Filing
- 2004-01-09 EP EP04701023A patent/EP1583759A1/en not_active Withdrawn
- 2004-01-09 RS YUP-2005/0528A patent/RS20050528A/sr unknown
- 2004-01-09 CN CNB200480003357XA patent/CN100457752C/zh not_active Expired - Fee Related
- 2004-01-09 CA CA002512184A patent/CA2512184A1/en not_active Abandoned
- 2004-01-09 PL PL378326A patent/PL378326A1/pl not_active Application Discontinuation
- 2004-01-09 BR BR0406669-3A patent/BRPI0406669A/pt not_active IP Right Cessation
- 2004-01-09 KR KR1020057012621A patent/KR20050095601A/ko not_active Application Discontinuation
- 2004-01-09 MX MXPA05007435A patent/MXPA05007435A/es active IP Right Grant
- 2004-01-09 AU AU2004203943A patent/AU2004203943B2/en not_active Ceased
- 2004-01-09 NZ NZ541087A patent/NZ541087A/en unknown
- 2004-01-09 JP JP2006500151A patent/JP2006516271A/ja active Pending
- 2004-01-09 EA EA200501104A patent/EA008539B1/ru not_active IP Right Cessation
- 2004-01-09 US US10/541,677 patent/US7482340B2/en not_active Expired - Fee Related
- 2004-09-01 UA UAA200507847A patent/UA81941C2/uk unknown
-
2005
- 2005-06-28 IL IL169435A patent/IL169435A0/en unknown
- 2005-08-02 IS IS7969A patent/IS7969A/is unknown
- 2005-08-03 NO NO20053730A patent/NO20053730L/no not_active Application Discontinuation
- 2005-08-08 HR HR20050703A patent/HRP20050703A2/hr not_active Application Discontinuation
-
2006
- 2006-01-24 ZA ZA200505461A patent/ZA200505461B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7482340B2 (en) | 2009-01-27 |
| NZ541087A (en) | 2008-04-30 |
| CN1745078A (zh) | 2006-03-08 |
| CA2512184A1 (en) | 2004-07-29 |
| BRPI0406669A (pt) | 2005-12-20 |
| NO20053730L (no) | 2005-10-07 |
| JP2006516271A (ja) | 2006-06-29 |
| FI20030030A0 (fi) | 2003-01-09 |
| IS7969A (is) | 2005-08-02 |
| IL169435A0 (en) | 2007-07-04 |
| UA81941C2 (uk) | 2008-02-25 |
| ZA200505461B (en) | 2006-03-29 |
| AU2004203943B2 (en) | 2009-09-17 |
| EP1583759A1 (en) | 2005-10-12 |
| EA200501104A1 (ru) | 2005-12-29 |
| AU2004203943A1 (en) | 2004-07-29 |
| PL378326A1 (pl) | 2006-03-20 |
| KR20050095601A (ko) | 2005-09-29 |
| HRP20050703A2 (en) | 2005-10-31 |
| US20060241147A1 (en) | 2006-10-26 |
| WO2004063191A1 (en) | 2004-07-29 |
| MXPA05007435A (es) | 2005-09-12 |
| CN100457752C (zh) | 2009-02-04 |
| EA008539B1 (ru) | 2007-06-29 |
| AR042733A1 (es) | 2005-06-29 |
| NO20053730D0 (no) | 2005-08-03 |
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