RS20050018A - Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors - Google Patents
Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptorsInfo
- Publication number
- RS20050018A RS20050018A YUP-2005/0018A YUP20050018A RS20050018A RS 20050018 A RS20050018 A RS 20050018A YU P20050018 A YUP20050018 A YU P20050018A RS 20050018 A RS20050018 A RS 20050018A
- Authority
- RS
- Serbia
- Prior art keywords
- derivatives
- ligands
- receptors
- acyloxypyrrolidine
- alkyl
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Ovaj pronalazak se odnosi na derivate aciloksipirolidina opšte formule (I): gde su: R1 predstavlja atom vodonika, (C1-C6)alkil, (C3-C6)cikloalkil, grupa -CH2CH2COOH ili grupa - NR2R3; R2 i R3 svako nezavisno, predstavljaju atom vodonika ili (C1-C6)alkil, na psotupak njihovog dobijanja i primenu u terapeutskoj praksi.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0209242A FR2842527B1 (fr) | 2002-07-19 | 2002-07-19 | Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique |
| PCT/FR2003/002262 WO2004009585A2 (fr) | 2002-07-19 | 2003-07-17 | Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b et v1a de avp |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS20050018A true RS20050018A (en) | 2007-06-04 |
Family
ID=29797610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YUP-2005/0018A RS20050018A (en) | 2002-07-19 | 2003-07-17 | Acyloxypyrrolidine derivatives and use thereof as ligands of v1b or both v1b and v1a receptors |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7202267B2 (sr) |
| EP (1) | EP1525198B1 (sr) |
| JP (1) | JP4264414B2 (sr) |
| CN (1) | CN100425608C (sr) |
| AR (1) | AR040571A1 (sr) |
| AT (1) | ATE312092T1 (sr) |
| AU (1) | AU2003271815B8 (sr) |
| BR (1) | BR0312800A (sr) |
| CA (1) | CA2492224A1 (sr) |
| DE (1) | DE60302670T2 (sr) |
| DK (1) | DK1525198T3 (sr) |
| EA (1) | EA008444B1 (sr) |
| ES (1) | ES2254962T3 (sr) |
| FR (1) | FR2842527B1 (sr) |
| HK (1) | HK1074444A1 (sr) |
| HR (1) | HRP20041231A2 (sr) |
| IL (1) | IL165942A (sr) |
| IS (1) | IS2487B (sr) |
| ME (1) | MEP12408A (sr) |
| MX (1) | MXPA05000822A (sr) |
| NO (1) | NO20050292L (sr) |
| NZ (1) | NZ537615A (sr) |
| PL (1) | PL375309A1 (sr) |
| RS (1) | RS20050018A (sr) |
| TW (1) | TWI274751B (sr) |
| UA (1) | UA78805C2 (sr) |
| WO (1) | WO2004009585A2 (sr) |
| ZA (1) | ZA200500478B (sr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005021534A1 (ja) | 2003-08-28 | 2005-03-10 | Taisho Pharmaceutical Co., Ltd. | １，３−ジヒドロ−２ｈ−インドール−２−オン誘導体 |
| TW200643015A (en) | 2005-03-11 | 2006-12-16 | Akzo Nobel Nv | 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives |
| DE102005015957A1 (de) * | 2005-03-31 | 2006-10-05 | Abbott Gmbh & Co. Kg | Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung |
| CA2610400A1 (en) | 2005-06-07 | 2006-12-14 | Pharmacopeia, Inc. | Azinone and diazinone v3 inhibitors for depression and stress disorders |
| RU2009113612A (ru) | 2006-09-11 | 2010-10-20 | Н.В. Органон (Nl) | Ацетамидные производные хиназолинона и изохинолинона |
| CN103864658B (zh) * | 2014-03-06 | 2016-06-15 | 南京工业大学 | 氮杂环丁酮衍生物及其制备方法与应用 |
| CN104447489B (zh) * | 2014-12-29 | 2017-01-11 | 南京工业大学 | 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2804114B1 (fr) * | 2000-01-25 | 2002-03-08 | Sanofi Synthelabo | Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant |
-
2002
- 2002-07-19 FR FR0209242A patent/FR2842527B1/fr not_active Expired - Fee Related
-
2003
- 2003-07-15 AR AR20030102539A patent/AR040571A1/es unknown
- 2003-07-17 EA EA200500032A patent/EA008444B1/ru not_active IP Right Cessation
- 2003-07-17 MX MXPA05000822A patent/MXPA05000822A/es active IP Right Grant
- 2003-07-17 RS YUP-2005/0018A patent/RS20050018A/sr unknown
- 2003-07-17 CN CNB038218178A patent/CN100425608C/zh not_active Expired - Fee Related
- 2003-07-17 DE DE60302670T patent/DE60302670T2/de not_active Expired - Lifetime
- 2003-07-17 AT AT03753652T patent/ATE312092T1/de active
- 2003-07-17 EP EP03753652A patent/EP1525198B1/fr not_active Expired - Lifetime
- 2003-07-17 DK DK03753652T patent/DK1525198T3/da active
- 2003-07-17 ME MEP-124/08A patent/MEP12408A/xx unknown
- 2003-07-17 CA CA002492224A patent/CA2492224A1/en not_active Abandoned
- 2003-07-17 BR BR0312800-8A patent/BR0312800A/pt not_active IP Right Cessation
- 2003-07-17 UA UAA200500286A patent/UA78805C2/uk unknown
- 2003-07-17 PL PL03375309A patent/PL375309A1/xx not_active IP Right Cessation
- 2003-07-17 WO PCT/FR2003/002262 patent/WO2004009585A2/fr active IP Right Grant
- 2003-07-17 AU AU2003271815A patent/AU2003271815B8/en not_active Ceased
- 2003-07-17 JP JP2004522252A patent/JP4264414B2/ja not_active Expired - Fee Related
- 2003-07-17 NZ NZ537615A patent/NZ537615A/en not_active IP Right Cessation
- 2003-07-17 ES ES03753652T patent/ES2254962T3/es not_active Expired - Lifetime
- 2003-07-18 TW TW092119736A patent/TWI274751B/zh not_active IP Right Cessation
-
2004
- 2004-12-22 IL IL165942A patent/IL165942A/en not_active IP Right Cessation
- 2004-12-30 HR HR20041231A patent/HRP20041231A2/hr not_active Application Discontinuation
-
2005
- 2005-01-12 IS IS7641A patent/IS2487B/is unknown
- 2005-01-18 ZA ZA200500478A patent/ZA200500478B/xx unknown
- 2005-01-19 US US11/038,384 patent/US7202267B2/en not_active Expired - Fee Related
- 2005-01-19 NO NO20050292A patent/NO20050292L/no not_active Application Discontinuation
- 2005-09-23 HK HK05108399A patent/HK1074444A1/xx not_active IP Right Cessation
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