RO88521A - Procedeu pentru obtinerea unui preparat coronarian - Google Patents

Procedeu pentru obtinerea unui preparat coronarian

Info

Publication number
RO88521A
RO88521A RO7272017A RO7201772A RO88521A RO 88521 A RO88521 A RO 88521A RO 7272017 A RO7272017 A RO 7272017A RO 7201772 A RO7201772 A RO 7201772A RO 88521 A RO88521 A RO 88521A
Authority
RO
Romania
Prior art keywords
coronary
procedure
obtaining
preparation
coronary preparation
Prior art date
Application number
RO7272017A
Other languages
English (en)
French (fr)
Other versions
RO88521B (ro
Inventor
Friedrich Bossert
Wulf Vater
Kurt Bauer
Karl H Adams
Original Assignee
Bayer Ag,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25761638&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO88521(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19722209526 external-priority patent/DE2209526C3/de
Application filed by Bayer Ag,De filed Critical Bayer Ag,De
Publication of RO88521A publication Critical patent/RO88521A/ro
Publication of RO88521B publication Critical patent/RO88521B/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S206/00—Special receptacle or package
    • Y10S206/828—Medicinal content

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Hydrogenated Pyridines (AREA)
RO72017A 1971-08-24 1972-08-22 Procedeu pentru obtinerea unui preparat coronarian RO88521B (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2142316 1971-08-24
DE19722209526 DE2209526C3 (de) 1972-02-29 1972-02-29 Coronartherapeutlkum in Form von Gelatine-BeiBkapseln

Publications (2)

Publication Number Publication Date
RO88521A true RO88521A (ro) 1987-04-30
RO88521B RO88521B (ro) 1987-05-01

Family

ID=25761638

Family Applications (1)

Application Number Title Priority Date Filing Date
RO72017A RO88521B (ro) 1971-08-24 1972-08-22 Procedeu pentru obtinerea unui preparat coronarian

Country Status (25)

Country Link
US (1) US3784684A (ro)
JP (2) JPS5434048B2 (ro)
KR (1) KR780000433B1 (ro)
BE (1) BE787951A (ro)
BG (1) BG27728A3 (ro)
CA (1) CA981582A (ro)
CY (1) CY918A (ro)
DD (1) DD99729A5 (ro)
DK (1) DK130628B (ro)
EG (1) EG10633A (ro)
ES (1) ES406047A1 (ro)
FI (1) FI53922C (ro)
FR (1) FR2150848B1 (ro)
GB (1) GB1362627A (ro)
HK (1) HK44877A (ro)
IE (1) IE36891B1 (ro)
IL (1) IL40165A (ro)
KE (1) KE2756A (ro)
LU (1) LU65929A1 (ro)
MY (1) MY7800003A (ro)
NL (1) NL176836C (ro)
NO (1) NO138167C (ro)
RO (1) RO88521B (ro)
SG (1) SG34877G (ro)
SU (1) SU432703A3 (ro)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU432703A3 (ro) * 1971-08-24 1974-06-15 Фридрих Боссерт, Вульф Фатер, Курт Бауер
ZA725808B (en) * 1971-08-24 1973-05-30 Bayer Ag A coronary agent in special form and processes for its manufacture
US4198391A (en) * 1973-07-20 1980-04-15 R. P. Scherer Ltd. Pharmaceutical compositions
GB1481411A (en) * 1973-07-20 1977-07-27 Scherer Ltd R Pharmaceutical compositions
BE825842A (fr) * 1974-02-22 1975-08-21 Compositions pharmaceutiques comprenant de la digoxine
US4002718A (en) * 1974-10-16 1977-01-11 Arnar-Stone Laboratories, Inc. Gelatin-encapsulated digoxin solutions and method of preparing the same
US4056610A (en) * 1975-04-09 1977-11-01 Minnesota Mining And Manufacturing Company Microcapsule insecticide composition
JPS52151724A (en) * 1976-06-07 1977-12-16 Takeda Chem Ind Ltd Hard shell gelatin capsule
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
JPS5484023A (en) * 1977-12-19 1979-07-04 Teijin Ltd Soft capsule containing active vitamin d3, and its preparation
JPS5522631A (en) * 1978-08-07 1980-02-18 Ota Seiyaku Kk Readily absorbable nifedipine preparation
JPS5522645A (en) * 1978-08-07 1980-02-18 Fujisawa Pharmaceut Co Ltd Soft capsule for encapsulation of light-unstable compound
US5264446A (en) * 1980-09-09 1993-11-23 Bayer Aktiengesellschaft Solid medicament formulations containing nifedipine, and processes for their preparation
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
JPS5939827A (ja) * 1982-08-27 1984-03-05 Nitto Electric Ind Co Ltd 医療用外用部材
DE3307353C2 (de) * 1983-03-02 1985-01-31 R.P. Scherer GmbH, 6930 Eberbach Polyethylenglykolhaltige Weichgelatinekapsel und Verfahren zu ihrer Herstellung
GB8305693D0 (en) * 1983-03-02 1983-04-07 Scherer Ltd R P Pharmaceutical compositions
DE3307422A1 (de) * 1983-03-03 1984-09-06 Bayer Ag, 5090 Leverkusen Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen
US4832952A (en) * 1983-07-07 1989-05-23 American Home Products Corporation Pharmaceutical composition containing a liquid lubricant
US4777048A (en) * 1983-07-07 1988-10-11 American Home Products Corporation Pharmaceutical composition containing a liquid lubricant
US4620974A (en) * 1983-07-07 1986-11-04 American Home Products Corporation Pharmaceutical composition containing a liquid lubricant
ATE33348T1 (de) * 1983-11-30 1988-04-15 Siegfried Ag Coronartherapeutikum in form von weichgelatinekapseln.
DE3419129A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Nifedipinpraeparate und verfahren zu ihrer herstellung
DE3419130A1 (de) * 1984-05-23 1985-11-28 Bayer Ag, 5090 Leverkusen Nifedipinkombinationspraeparate und verfahren zu ihrer herstellung
US5266581A (en) * 1984-07-04 1993-11-30 Bayer Aktiengesellschaft Solid composition containing dihydropyridine, PVP and PVPP
EP0175671A1 (de) * 1984-08-23 1986-03-26 Kuhlemann & Co. Pharmazeutische Zubereitung sowie Verfahren zum Darreichen dieser pharmazeutischen Zubereitung
DE3438830A1 (de) * 1984-10-23 1986-04-30 Rentschler Arzneimittel Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
DE3532129A1 (de) * 1985-09-10 1987-03-12 Bayer Ag Ss-carotin enthaltende gelatine
GB8522453D0 (en) * 1985-09-11 1985-10-16 Lilly Industries Ltd Chewable capsules
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
US4689233A (en) * 1986-01-06 1987-08-25 Siegfried Aktiengesellschaft Coronary therapeutic agent in the form of soft gelatin capsules
US4656028A (en) * 1986-06-24 1987-04-07 Norcliff Thayer Inc. Encapsulated antacid
DE3636123A1 (de) * 1986-10-23 1988-05-05 Rentschler Arzneimittel Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten
DE3639418A1 (de) * 1986-11-18 1988-06-09 Forschungsgesellschaft Rauchen Nikotinhaltiges mittel
GB8629761D0 (en) * 1986-12-12 1987-01-21 Harris Pharma Ltd Capsules
DE3682208D1 (de) * 1986-12-18 1991-11-28 Kurt Heinz Bauer Gegenueber lichteinfluss stabilisiertes nifedipin-konzentrat und verfahren zu seiner herstellung.
DE3714402A1 (de) * 1987-04-30 1988-11-10 Kali Chemie Pharma Gmbh Arzneimittelformulierung
DE3738236A1 (de) * 1987-11-11 1989-05-24 Euro Celtique Sa Beisskapsel
US4954346A (en) * 1988-06-08 1990-09-04 Ciba-Geigy Corporation Orally administrable nifedipine solution in a solid light resistant dosage form
US4935243A (en) * 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
CA2056032A1 (en) * 1990-11-29 1992-05-30 Minoru Aoki Hard capsule preparation
US5431916A (en) * 1993-04-29 1995-07-11 The Procter & Gamble Company Pharmaceutical compositions and process of manufacture thereof
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US6726930B1 (en) 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
AU2190697A (en) * 1996-04-12 1997-11-07 Flemington Pharmaceutical Corporation Buccal polar spray or capsule
ATE417604T1 (de) 1996-07-08 2009-01-15 Penwest Pharmaceuticals Co Matrix mit verzögerter freisetzung für hochdosierte unlösliche arzneistoffe
JP4730985B2 (ja) * 1997-09-10 2011-07-20 武田薬品工業株式会社 安定化された医薬製剤
US20040136913A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing sumatriptan
US20050180923A1 (en) * 1997-10-01 2005-08-18 Dugger Harry A.Iii Buccal, polar and non-polar spray containing testosterone
US20030077228A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20050002867A1 (en) * 1997-10-01 2005-01-06 Novadel Pharma Inc. Buccal, polar and non-polar sprays containing propofol
US20040136915A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing atropine
US20030095927A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20050163719A1 (en) * 1997-10-01 2005-07-28 Dugger Harry A.Iii Buccal, polar and non-polar spray containing diazepam
ES2293875T3 (es) * 1997-10-01 2008-04-01 Novadel Pharma Inc. Aerosol bucal no polar.
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20040141923A1 (en) * 1997-10-01 2004-07-22 Dugger Harry A. Buccal, polar and non-polar spray containing alprazolam
US20030190286A1 (en) * 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US20050287075A1 (en) * 1997-10-01 2005-12-29 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20090162300A1 (en) * 1997-10-01 2009-06-25 Dugger Iii Harry A Buccal, polar and non-polar spray containing alprazolam
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US20050281752A1 (en) * 1997-10-01 2005-12-22 Dugger Harry A Iii Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030077227A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
US20030082107A1 (en) * 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20040136914A1 (en) * 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US20030095926A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US7632517B2 (en) * 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US20030102246A1 (en) * 1999-03-20 2003-06-05 Lts Lohmann Therapie-Systeme Ag Method for improving the stability of stored and/or used light-sensitive therapeutic systems or components thereof
AU6866900A (en) * 1999-08-31 2001-03-26 Chugai Seiyaku Kabushiki Kaisha Soft capsules
CA2352211C (en) * 1999-09-30 2009-03-24 Edward Mendell Co., Inc. Sustained release matrix systems for highly soluble drugs
WO2002087543A1 (en) * 2001-05-01 2002-11-07 Biozone Laboratories, Inc. Sustained release formulations for nifedipine, dextromethorphan, and danazol
US20030070679A1 (en) * 2001-06-01 2003-04-17 Boehringer Ingelheim Pharma Kg Capsules containing inhalable tiotropium
ATE387191T1 (de) 2002-04-25 2008-03-15 Banner Pharmacaps Inc Kaubare weichkapsel
EP1502588B1 (en) * 2002-05-09 2013-03-06 Chugai Seiyaku Kabushiki Kaisha Light-stabilized soft capsule for formulations
UA92920C2 (ru) * 2005-10-31 2010-12-27 Кова Ко., Лтд. Таблетка с насечкой, включающая питавастатин, и имеющая превосходную фотостабильность
JP2009534387A (ja) * 2006-04-19 2009-09-24 ノヴァデル ファーマ インコーポレイテッド 安定な含水アルコール性経口噴霧調剤物および方法
US20080171089A1 (en) * 2006-12-22 2008-07-17 Blondino Frank E Stable anti-nausea oral spray formulations and methods
WO2008141264A1 (en) * 2007-05-10 2008-11-20 Novadel Pharma Inc. Anti-insomnia compositions and methods
US7985325B2 (en) * 2007-10-30 2011-07-26 Novellus Systems, Inc. Closed contact electroplating cup assembly
WO2009091622A1 (en) * 2008-01-18 2009-07-23 Dow Global Technologies Inc. Method to enhance aqueous solubility of poorly soluble actives using methoxypolyethylene glycol
WO2010087462A1 (ja) * 2009-01-29 2010-08-05 大日本住友製薬株式会社 内核を有する口腔内崩壊錠
CN102160872A (zh) 2010-02-23 2011-08-24 天津天士力制药股份有限公司 复方丹参滴丸胶囊
TWI571257B (zh) * 2011-02-23 2017-02-21 Tasly Pharmaceutical Group Co Capsule preparation
EP3925602A1 (en) 2018-05-14 2021-12-22 Capsugel Belgium NV Capsules with opacifier
JP7470647B2 (ja) 2018-06-14 2024-04-18 アストラゼネカ・ユーケイ・リミテッド ジヒドロピリジン型カルシウムチャネル遮断薬医薬組成物を用いて血圧を低下させるための方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870061A (en) * 1956-11-08 1959-01-20 Mead Johnson & Co Concentrates of dialkyl sulfosuccinates
US3155587A (en) * 1963-01-23 1964-11-03 American Cyanamid Co Stable liquid preparations of 7-chlorotetracycline
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
SU432703A3 (ro) * 1971-08-24 1974-06-15 Фридрих Боссерт, Вульф Фатер, Курт Бауер

Also Published As

Publication number Publication date
FI53922B (fi) 1978-05-31
DK130628B (da) 1975-03-17
CY918A (en) 1977-12-23
FR2150848B1 (ro) 1976-04-16
JPS5434048B2 (ro) 1979-10-24
DK130628C (ro) 1975-08-25
NL176836C (nl) 1985-06-17
IE36891L (en) 1973-02-24
FR2150848A1 (ro) 1973-04-13
KR780000433B1 (en) 1978-10-14
NL7211565A (ro) 1973-02-27
JPS53121921A (en) 1978-10-24
KE2756A (en) 1977-10-14
JPS4828621A (ro) 1973-04-16
NO138167B (no) 1978-04-10
NO138167C (no) 1978-07-26
MY7800003A (en) 1978-12-31
BG27728A3 (en) 1979-12-12
FI53922C (fi) 1979-09-07
IL40165A (en) 1975-03-13
SU432703A3 (ro) 1974-06-15
GB1362627A (en) 1974-08-07
BE787951A (fr) 1973-02-26
ES406047A1 (es) 1981-08-16
IL40165A0 (en) 1972-10-29
CA981582A (en) 1976-01-13
EG10633A (en) 1976-08-31
DD99729A5 (ro) 1973-08-20
RO88521B (ro) 1987-05-01
SG34877G (en) 1987-04-03
US3784684A (en) 1974-01-08
LU65929A1 (ro) 1973-01-15
IE36891B1 (en) 1977-03-16
HK44877A (en) 1977-09-09
NL176836B (nl) 1985-01-16

Similar Documents

Publication Publication Date Title
RO88521A (ro) Procedeu pentru obtinerea unui preparat coronarian
NO141804C (no) Fotopolymeriserbart preparat
BG21027A3 (bg) Метод за получаване на изотиоцианобензазоли
IT950664B (it) Procedimento radiogoniometrico
NO145918C (no) Fremgangsmaate for fremstilling av 7-acylamido-3-cefem-4-karboksylsyrer
TR17434A (tr) Guemues aslinda katalizoerlerin hazirlanmasi icin usul
NO139486C (no) Fremgangsmaate for fremstilling av en vaskemiddelblanding
IT969896B (it) Procedimento per fabbricare zeaxantina
RO69106A (ro) Procedeu de preparare a fenilpiridazinelor
SE417207B (sv) Foerfarande foer framstaellning av en 3-metylencefalosporinfoerening
IT958504B (it) Procedimento per produrre alchenil silani
SE395455B (sv) Forfarande for framstellning av 3-(fenyl-piperazinyl) etylindoliner
SE398343B (sv) Forfarande for framstellning av porosa formkroppar
BG26666A3 (bg) Метод за получаване на капролактам
NO136561C (no) Preparat for setting av h}r.
SE417711B (sv) Forfarande for framstellning av 5-iminometyl-2-nitroimidazolderivat
BR7204278D0 (pt) Um multiplenor
BG20777A3 (bg) Метод за получаване на 4- /-4 -бифенилил/-1-бутанол
SE391332B (sv) Forfarande for framstellning av en fenyletanolamin
NO136836C (no) Fremgangsm}te til fremstilling av hydrokinon
SE393376B (sv) Forfarande for framstellning av pyrimidinonderivat
BG20562A3 (bg) Метод за получаване на халогенацетанилиди
IT966747B (it) Procedimento per preparare dinitroantrachinoni
SE405119B (sv) Forfarande for framstellning av 2,4-diamino-5-bensyl-pyrimidiner
SE402454B (sv) Forfarande for framstellning av 2-alkoxi-5-alkylsulfonyl-toluen