RO82739A - Procedeu pentru prepararea unor derivati de fluoerena - Google Patents

Procedeu pentru prepararea unor derivati de fluoerena

Info

Publication number
RO82739A
RO82739A RO81104045A RO10404581A RO82739A RO 82739 A RO82739 A RO 82739A RO 81104045 A RO81104045 A RO 81104045A RO 10404581 A RO10404581 A RO 10404581A RO 82739 A RO82739 A RO 82739A
Authority
RO
Romania
Prior art keywords
preparation
fluorene derivatives
fluorene
derivatives
Prior art date
Application number
RO81104045A
Other languages
English (en)
French (fr)
Other versions
RO82739B (ro
Inventor
Edward R Lavagnino
Andrew J Pike
Jack B Campbell
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO82739A publication Critical patent/RO82739A/ro
Publication of RO82739B publication Critical patent/RO82739B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO104045A 1980-04-17 1981-04-16 Procedeu pentru prepararea unor derivati de fluoerena RO82739B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/141,229 US4282170A (en) 1980-04-17 1980-04-17 9-Carbamoyl-9-(2-cyanoethyl)fluorenes

Publications (2)

Publication Number Publication Date
RO82739A true RO82739A (ro) 1984-01-14
RO82739B RO82739B (ro) 1984-01-30

Family

ID=22494758

Family Applications (1)

Application Number Title Priority Date Filing Date
RO104045A RO82739B (ro) 1980-04-17 1981-04-16 Procedeu pentru prepararea unor derivati de fluoerena

Country Status (26)

Country Link
US (1) US4282170A (ro)
EP (1) EP0038676B1 (ro)
JP (2) JPS574954A (ro)
KR (1) KR840001071B1 (ro)
AR (1) AR228596A1 (ro)
AT (1) ATE9897T1 (ro)
AU (1) AU543345B2 (ro)
BG (1) BG35464A3 (ro)
CA (1) CA1172646A (ro)
CS (1) CS225833B2 (ro)
DD (1) DD158395A5 (ro)
DE (1) DE3166679D1 (ro)
DK (1) DK172181A (ro)
ES (1) ES501339A0 (ro)
FI (1) FI75337C (ro)
GB (1) GB2074161B (ro)
GR (1) GR73824B (ro)
IE (1) IE51221B1 (ro)
IL (1) IL62669A (ro)
NZ (1) NZ196814A (ro)
PH (1) PH15857A (ro)
PL (1) PL131122B1 (ro)
PT (1) PT72854B (ro)
RO (1) RO82739B (ro)
SU (1) SU1297724A3 (ro)
ZA (1) ZA812482B (ro)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552982A (en) * 1983-08-01 1985-11-12 Eli Lilly And Company Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) * 1983-09-21 1985-04-02 Eli Lilly And Company Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
US4585894A (en) * 1983-10-19 1986-04-29 Eli Lilly And Company Process for producing 9-carbamoyl fluorene derivatives
IL73261A (en) * 1983-10-19 1988-03-31 Lilly Co Eli Process for producing 9-carbamoyl-9-aminoalkyl fluorene derivatives,and certain intermediates thereof
US4486592A (en) * 1983-10-19 1984-12-04 Eli Lilly And Company 9-Carbamoylfluorene derivatives
US4842420A (en) * 1987-12-14 1989-06-27 Mobil Oil Corporation Variable-width draw tape for thermoplastic bags
US5736578A (en) * 1995-06-06 1998-04-07 Bristol-Myers Squibb Company Ethylamido fluorenes and improved method of making same
JP4129993B2 (ja) * 1996-01-16 2008-08-06 ブリストル―マイヤーズ・スクイブ・カンパニー ミクロソーム・トリグリセリド転移プロテインの立体配座制限芳香族抑制剤および方法
US5760246A (en) * 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
CN100463249C (zh) * 2006-01-24 2009-02-18 吉林大学 电化学沉积制备有机发光薄膜的方法及在发光器件中的应用
US7520124B2 (en) * 2006-09-12 2009-04-21 United Technologies Corporation Asymmetric serrated nozzle for exhaust noise reduction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2280058A (en) * 1942-04-21 Cyanoethylation of carbocycijc
GB960758A (en) 1962-12-21 1964-06-17 Boehringer & Soehne Gmbh Basic fluorene derivatives
US3325544A (en) * 1965-06-10 1967-06-13 Upjohn Co 9-(2-amino-1-methylethyl) fluoren-9-ol and salts thereof
US3660485A (en) * 1970-10-05 1972-05-02 Searle & Co Fluorene-9-carboxylic acid hydrazides
US3843657A (en) * 1972-12-08 1974-10-22 Searle & Co 9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

Also Published As

Publication number Publication date
EP0038676A1 (en) 1981-10-28
GB2074161A (en) 1981-10-28
IL62669A0 (en) 1981-06-29
FI811176L (fi) 1981-10-18
RO82739B (ro) 1984-01-30
JPH01125363A (ja) 1989-05-17
ES8302632A1 (es) 1983-01-16
IE51221B1 (en) 1986-11-12
AU6961181A (en) 1981-10-22
PL131122B1 (en) 1984-10-31
CA1172646A (en) 1984-08-14
ES501339A0 (es) 1983-01-16
GB2074161B (en) 1984-03-14
JPH0149701B2 (ro) 1989-10-25
DE3166679D1 (en) 1984-11-22
EP0038676B1 (en) 1984-10-17
GR73824B (ro) 1984-05-03
JPS574954A (en) 1982-01-11
NZ196814A (en) 1984-07-06
KR840001071B1 (ko) 1984-07-31
AR228596A1 (es) 1983-03-30
PT72854A (en) 1981-05-01
BG35464A3 (en) 1984-04-15
PH15857A (en) 1983-04-13
US4282170A (en) 1981-08-04
PT72854B (en) 1982-03-30
FI75337B (fi) 1988-02-29
JPH0153267B2 (ro) 1989-11-13
PL230714A1 (ro) 1982-08-02
AU543345B2 (en) 1985-04-18
ATE9897T1 (de) 1984-11-15
FI75337C (fi) 1988-06-09
DD158395A5 (de) 1983-01-12
CS225833B2 (en) 1984-02-13
SU1297724A3 (ru) 1987-03-15
IL62669A (en) 1984-06-29
IE810873L (en) 1981-10-17
DK172181A (da) 1981-10-18
KR830005110A (ko) 1983-07-23
ZA812482B (en) 1982-11-24

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