ATE9897T1 - Verfahren zur herstellung von fluorenderivaten. - Google Patents

Verfahren zur herstellung von fluorenderivaten.

Info

Publication number
ATE9897T1
ATE9897T1 AT81301666T AT81301666T ATE9897T1 AT E9897 T1 ATE9897 T1 AT E9897T1 AT 81301666 T AT81301666 T AT 81301666T AT 81301666 T AT81301666 T AT 81301666T AT E9897 T1 ATE9897 T1 AT E9897T1
Authority
AT
Austria
Prior art keywords
production
fluorine derivatives
fluorine
derivatives
Prior art date
Application number
AT81301666T
Other languages
English (en)
Inventor
Edward Ralph Lavagnino
Andrew Joseph Pike
Jack Beuford Campbell
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Application granted granted Critical
Publication of ATE9897T1 publication Critical patent/ATE9897T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/29—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton containing cyano groups and acylated amino groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT81301666T 1980-04-17 1981-04-15 Verfahren zur herstellung von fluorenderivaten. ATE9897T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/141,229 US4282170A (en) 1980-04-17 1980-04-17 9-Carbamoyl-9-(2-cyanoethyl)fluorenes

Publications (1)

Publication Number Publication Date
ATE9897T1 true ATE9897T1 (de) 1984-11-15

Family

ID=22494758

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81301666T ATE9897T1 (de) 1980-04-17 1981-04-15 Verfahren zur herstellung von fluorenderivaten.

Country Status (26)

Country Link
US (1) US4282170A (de)
EP (1) EP0038676B1 (de)
JP (2) JPS574954A (de)
KR (1) KR840001071B1 (de)
AR (1) AR228596A1 (de)
AT (1) ATE9897T1 (de)
AU (1) AU543345B2 (de)
BG (1) BG35464A3 (de)
CA (1) CA1172646A (de)
CS (1) CS225833B2 (de)
DD (1) DD158395A5 (de)
DE (1) DE3166679D1 (de)
DK (1) DK172181A (de)
ES (1) ES501339A0 (de)
FI (1) FI75337C (de)
GB (1) GB2074161B (de)
GR (1) GR73824B (de)
IE (1) IE51221B1 (de)
IL (1) IL62669A (de)
NZ (1) NZ196814A (de)
PH (1) PH15857A (de)
PL (1) PL131122B1 (de)
PT (1) PT72854B (de)
RO (1) RO82739B (de)
SU (1) SU1297724A3 (de)
ZA (1) ZA812482B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552982A (en) * 1983-08-01 1985-11-12 Eli Lilly And Company Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) * 1983-09-21 1985-04-02 Eli Lilly And Company Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
IL73261A (en) * 1983-10-19 1988-03-31 Lilly Co Eli Process for producing 9-carbamoyl-9-aminoalkyl fluorene derivatives,and certain intermediates thereof
US4486592A (en) * 1983-10-19 1984-12-04 Eli Lilly And Company 9-Carbamoylfluorene derivatives
US4585894A (en) * 1983-10-19 1986-04-29 Eli Lilly And Company Process for producing 9-carbamoyl fluorene derivatives
US4842420A (en) * 1987-12-14 1989-06-27 Mobil Oil Corporation Variable-width draw tape for thermoplastic bags
US5736578A (en) * 1995-06-06 1998-04-07 Bristol-Myers Squibb Company Ethylamido fluorenes and improved method of making same
PL328094A1 (en) * 1996-01-16 1999-01-04 Bristol Myers Squibb Co Conformingly restricted aromatic inhibitors triglycerides carrying chromosome protein and method of obtaining such inhibitors
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method
CN100463249C (zh) * 2006-01-24 2009-02-18 吉林大学 电化学沉积制备有机发光薄膜的方法及在发光器件中的应用
US7520124B2 (en) * 2006-09-12 2009-04-21 United Technologies Corporation Asymmetric serrated nozzle for exhaust noise reduction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2280058A (en) * 1942-04-21 Cyanoethylation of carbocycijc
NL287095A (de) 1962-12-21 1965-02-25
US3325544A (en) * 1965-06-10 1967-06-13 Upjohn Co 9-(2-amino-1-methylethyl) fluoren-9-ol and salts thereof
US3660485A (en) * 1970-10-05 1972-05-02 Searle & Co Fluorene-9-carboxylic acid hydrazides
US3843657A (en) * 1972-12-08 1974-10-22 Searle & Co 9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

Also Published As

Publication number Publication date
PT72854A (en) 1981-05-01
DE3166679D1 (en) 1984-11-22
JPH0153267B2 (de) 1989-11-13
GB2074161A (en) 1981-10-28
IE51221B1 (en) 1986-11-12
CS225833B2 (en) 1984-02-13
PH15857A (en) 1983-04-13
IL62669A0 (en) 1981-06-29
US4282170A (en) 1981-08-04
BG35464A3 (en) 1984-04-15
PL131122B1 (en) 1984-10-31
JPS574954A (en) 1982-01-11
RO82739A (ro) 1984-01-14
JPH01125363A (ja) 1989-05-17
ZA812482B (en) 1982-11-24
CA1172646A (en) 1984-08-14
DK172181A (da) 1981-10-18
EP0038676B1 (de) 1984-10-17
AU543345B2 (en) 1985-04-18
NZ196814A (en) 1984-07-06
FI811176L (fi) 1981-10-18
IL62669A (en) 1984-06-29
FI75337B (fi) 1988-02-29
PT72854B (en) 1982-03-30
PL230714A1 (de) 1982-08-02
FI75337C (fi) 1988-06-09
SU1297724A3 (ru) 1987-03-15
GR73824B (de) 1984-05-03
RO82739B (ro) 1984-01-30
JPH0149701B2 (de) 1989-10-25
ES8302632A1 (es) 1983-01-16
IE810873L (en) 1981-10-17
ES501339A0 (es) 1983-01-16
GB2074161B (en) 1984-03-14
EP0038676A1 (de) 1981-10-28
AU6961181A (en) 1981-10-22
DD158395A5 (de) 1983-01-12
KR840001071B1 (ko) 1984-07-31
KR830005110A (ko) 1983-07-23
AR228596A1 (es) 1983-03-30

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