RO69617A - Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani - Google Patents

Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Info

Publication number
RO69617A
RO69617A RO7589653A RO8965375A RO69617A RO 69617 A RO69617 A RO 69617A RO 7589653 A RO7589653 A RO 7589653A RO 8965375 A RO8965375 A RO 8965375A RO 69617 A RO69617 A RO 69617A
Authority
RO
Romania
Prior art keywords
benzomorphans
furfuryl
tetrahydro
preparation
Prior art date
Application number
RO7589653A
Other languages
English (en)
French (fr)
Romanian (ro)
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Steckhaus
Original Assignee
C.H.Boehringer Sohn,De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H.Boehringer Sohn,De filed Critical C.H.Boehringer Sohn,De
Publication of RO69617A publication Critical patent/RO69617A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
RO7589653A 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani RO69617A (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
RO69617A true RO69617A (ro) 1980-08-15

Family

ID=5909593

Family Applications (2)

Application Number Title Priority Date Filing Date
RO7589653A RO69617A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani
RO7589654A RO70051A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Family Applications After (1)

Application Number Title Priority Date Filing Date
RO7589654A RO70051A (ro) 1974-03-09 1975-03-07 Procedeu pentru prepararea unor 2-tetrahidrofurfuril-6,7-benzomorfani

Country Status (25)

Country Link
JP (1) JPS5827275B2 (enEXAMPLES)
AT (1) AT344332B (enEXAMPLES)
BE (1) BE826440A (enEXAMPLES)
BG (3) BG24814A4 (enEXAMPLES)
CA (1) CA1049511A (enEXAMPLES)
CH (8) CH612425A5 (enEXAMPLES)
CS (1) CS188221B2 (enEXAMPLES)
DD (1) DD119236A5 (enEXAMPLES)
DE (1) DE2411382C3 (enEXAMPLES)
DK (1) DK137188C (enEXAMPLES)
ES (6) ES440350A1 (enEXAMPLES)
FI (1) FI63571C (enEXAMPLES)
FR (1) FR2262984B1 (enEXAMPLES)
GB (1) GB1496418A (enEXAMPLES)
HU (1) HU177408B (enEXAMPLES)
IE (1) IE40945B1 (enEXAMPLES)
IL (1) IL46760A (enEXAMPLES)
NL (1) NL7502724A (enEXAMPLES)
NO (1) NO141800C (enEXAMPLES)
PH (1) PH14127A (enEXAMPLES)
PL (3) PL93700B1 (enEXAMPLES)
RO (2) RO69617A (enEXAMPLES)
SE (1) SE421919B (enEXAMPLES)
SU (3) SU577982A3 (enEXAMPLES)
ZA (1) ZA751394B (enEXAMPLES)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
DE122006000051I1 (de) * 1995-03-10 2007-01-04 Photocure Asa Ester der 5-Aminolevulins{ure als Mittel zur Photosensibillisierung in der Chemotherapie
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
US8859580B2 (en) 2007-11-16 2014-10-14 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
WO2009094169A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5730021B2 (ja) 2008-02-15 2015-06-03 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2300461B1 (en) 2008-05-01 2013-04-17 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en) 2008-05-13 2009-12-16 Boehringer Ingelheim Int Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
KR20110050459A (ko) 2008-07-25 2011-05-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
EP2440537A1 (en) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en) 2011-08-17 2014-05-27 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
SE421919B (sv) 1982-02-08
IE40945L (en) 1975-09-09
CH622015A5 (en) 1981-03-13
PH14127A (en) 1981-02-26
DK92975A (enEXAMPLES) 1975-09-10
FI63571C (fi) 1983-07-11
PL93499B1 (enEXAMPLES) 1977-05-30
CH612425A5 (en) 1979-07-31
JPS5827275B2 (ja) 1983-06-08
GB1496418A (en) 1977-12-30
FR2262984B1 (enEXAMPLES) 1978-07-28
FI63571B (fi) 1983-03-31
ES440347A1 (es) 1977-06-01
SU577982A3 (ru) 1977-10-25
ZA751394B (en) 1976-11-24
BG24814A4 (bg) 1978-05-12
ES440349A1 (es) 1977-03-01
AU7894275A (en) 1976-09-16
NO750773L (enEXAMPLES) 1975-09-10
IL46760A0 (en) 1975-05-22
DE2411382A1 (de) 1975-09-18
DD119236A5 (enEXAMPLES) 1976-04-12
AT344332B (de) 1978-07-10
CH620440A5 (en) 1980-11-28
ATA153875A (de) 1977-11-15
NO141800B (no) 1980-02-04
BG25087A3 (bg) 1978-07-12
SE7502592L (enEXAMPLES) 1975-09-10
IE40945B1 (en) 1979-09-12
FI750652A7 (enEXAMPLES) 1975-09-10
CH622016A5 (en) 1981-03-13
NO141800C (no) 1980-06-04
ES440345A1 (es) 1977-03-01
RO70051A (ro) 1980-12-30
SU577983A3 (ru) 1977-10-25
JPS50123675A (enEXAMPLES) 1975-09-29
CS188221B2 (en) 1979-02-28
DE2411382B2 (de) 1979-01-18
CA1049511A (en) 1979-02-27
BG24813A4 (bg) 1978-05-12
CH622014A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
SU588916A3 (ru) 1978-01-15
CH620439A5 (en) 1980-11-28
CH620681A5 (en) 1980-12-15
PL93700B1 (enEXAMPLES) 1977-06-30
HU177408B (en) 1981-10-28
DK137188B (da) 1978-01-30
FR2262984A1 (enEXAMPLES) 1975-10-03
BE826440A (fr) 1975-09-08
DE2411382C3 (de) 1979-09-06
IL46760A (en) 1978-12-17
DK137188C (da) 1978-07-03
NL7502724A (nl) 1975-09-11
ES440346A1 (es) 1977-03-01
PL93699B1 (enEXAMPLES) 1977-06-30
ES440350A1 (es) 1977-03-16
ES440348A1 (es) 1977-06-01

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