PY2052250A - Compuestos inhibidores de rip1 y métodos para fabricar y usar los mismos - Google Patents

Compuestos inhibidores de rip1 y métodos para fabricar y usar los mismos

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Publication number
PY2052250A
PY2052250A PY202002052250A PY2052250A PY2052250A PY 2052250 A PY2052250 A PY 2052250A PY 202002052250 A PY202002052250 A PY 202002052250A PY 2052250 A PY2052250 A PY 2052250A PY 2052250 A PY2052250 A PY 2052250A
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PY
Paraguay
Prior art keywords
rip1
manufacturing
methods
inhibiting compounds
inhibitor compounds
Prior art date
Application number
PY202002052250A
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English (en)
Inventor
Bhamidipati Somasekhar
Taylor Vanessa
Original Assignee
Rigel Pharmaceuticals Inc
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Publication date
Application filed by Rigel Pharmaceuticals Inc filed Critical Rigel Pharmaceuticals Inc
Publication of PY2052250A publication Critical patent/PY2052250A/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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Abstract

Se divulgan en el presente documento compuestos inhibidores de quinasas, tales como compuestos inhibidores de cinasas de la proteína-1 (RIP1) que interactúa con el recepetor, así como composiciones farmacétucias y combinaciones que comprenden dichos compuestos inhibidores. Los compuestos, composiciones farmacéuticas y/o combinaciones divulgados se pueden usar para tratar o prevenir una enfermedad o dolencia asociada a cinasa, particularmente una enfermedad o dolencia asociada a RIP1.
PY202002052250A 2019-09-06 2020-09-07 Compuestos inhibidores de rip1 y métodos para fabricar y usar los mismos PY2052250A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962897223P 2019-09-06 2019-09-06
US201962932404P 2019-11-07 2019-11-07
US202063001016P 2020-03-27 2020-03-27
US202063004301P 2020-04-02 2020-04-02
US202063004290P 2020-04-02 2020-04-02
US202063004319P 2020-04-02 2020-04-02

Publications (1)

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PY2052250A true PY2052250A (es) 2021-10-05

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PY202002052250A PY2052250A (es) 2019-09-06 2020-09-07 Compuestos inhibidores de rip1 y métodos para fabricar y usar los mismos
PY202002052241A PY2052241A (es) 2019-09-06 2020-09-07 Inhibidores heterocíclicos de la cinasa rip1

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EP (3) EP4025568B1 (es)
JP (4) JP7760493B2 (es)
KR (3) KR102824407B1 (es)
CN (3) CN115279763B (es)
AU (3) AU2020341681B2 (es)
BR (3) BR112022002991A2 (es)
CA (2) CA3149926A1 (es)
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DO (1) DOP2022000051A (es)
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PY (2) PY2052250A (es)
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CA3094197C (en) * 2015-07-02 2023-02-28 F. Hoffmann-La Roche Ag Bicyclic lactams and methods of use thereof
JP7349359B2 (ja) 2016-10-17 2023-09-22 エフ． ホフマン－ラ ロシュ アーゲー 二環式ピリドンラクタム及びその使用方法。
PE20211383A1 (es) 2018-05-03 2021-07-27 Rigel Pharmaceuticals Inc Compuestos inhibidores de rip1 y metodos para preparar y usar los mismos
IL278416B2 (en) 2018-05-03 2023-12-01 Rigel Pharmaceuticals Inc RIP1 inhibitory compounds and methods for their preparation and use
PE20221628A1 (es) * 2019-09-06 2022-10-19 Rigel Pharmaceuticals Inc Compuestos inhibidores de rip1 y metodos para hacer y utilizar los mismos
MX2022002717A (es) 2019-09-06 2022-08-10 Rigel Pharmaceuticals Inc Compuestos inhibidores de rip1 y metodos para prepararlos y usarlos.
HRP20251589T1 (hr) * 2019-11-07 2026-01-30 Rigel Pharmaceuticals, Inc. Heterociklični spojevi koji inhibiraju rip1
CN115515940A (zh) * 2020-02-28 2022-12-23 德州大学系统董事会 用于治疗疾病的受体相互作用蛋白激酶i的抑制剂
AR121717A1 (es) 2020-04-02 2022-06-29 Rigel Pharmaceuticals Inc Inhibidores de rip1k
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