PT98643A - Processo para a preparacao de uma composicao oftalmica em gotas contendo acido 3,4-dihidro-2,8-diisopropil-3-tioxo-2h-1,4-benzoxazina-4-acetico - Google Patents

Processo para a preparacao de uma composicao oftalmica em gotas contendo acido 3,4-dihidro-2,8-diisopropil-3-tioxo-2h-1,4-benzoxazina-4-acetico

Info

Publication number
PT98643A
PT98643A PT98643A PT9864391A PT98643A PT 98643 A PT98643 A PT 98643A PT 98643 A PT98643 A PT 98643A PT 9864391 A PT9864391 A PT 9864391A PT 98643 A PT98643 A PT 98643A
Authority
PT
Portugal
Prior art keywords
thioxo
diisopropyl
dihydro
acetic acid
benzoxazine
Prior art date
Application number
PT98643A
Other languages
English (en)
Other versions
PT98643B (pt
Inventor
Kazumichi Ushio
Yoshifumi Ikejiki
Original Assignee
Senju Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharma Co filed Critical Senju Pharma Co
Publication of PT98643A publication Critical patent/PT98643A/pt
Publication of PT98643B publication Critical patent/PT98643B/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PT98643A 1990-08-13 1991-08-12 Processo para a preparacao de uma composicao oftalmica em gotas contendo acido 3,4-dihidro-2,8-diisopropil-3-tioxo-2h-1,4-benzoxazina-4-acetico PT98643B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21482790 1990-08-13
JP16285491 1991-07-03

Publications (2)

Publication Number Publication Date
PT98643A true PT98643A (pt) 1992-07-31
PT98643B PT98643B (pt) 1999-01-29

Family

ID=26488494

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98643A PT98643B (pt) 1990-08-13 1991-08-12 Processo para a preparacao de uma composicao oftalmica em gotas contendo acido 3,4-dihidro-2,8-diisopropil-3-tioxo-2h-1,4-benzoxazina-4-acetico

Country Status (16)

Country Link
US (1) US5663170A (pt)
EP (1) EP0472327B1 (pt)
JP (1) JP2769253B2 (pt)
KR (1) KR920003971A (pt)
AT (1) ATE121295T1 (pt)
AU (1) AU633754B2 (pt)
CA (1) CA2048942A1 (pt)
DE (1) DE69109021T2 (pt)
DK (1) DK0472327T3 (pt)
ES (1) ES2071227T3 (pt)
FI (1) FI97777C (pt)
HU (1) HU207950B (pt)
NO (1) NO177845C (pt)
PT (1) PT98643B (pt)
RU (1) RU2068260C1 (pt)
TW (1) TW200402B (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993018764A2 (en) * 1992-03-18 1993-09-30 Coopervision Pharmaceuticals, Inc. VERAPAMIL HCl FORMULATION AND OTHER OPHTHALMIC SOLUTIONS WITH BUFFER SYSTEM FOR OCULAR ADMINISTRATION
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
US5472954A (en) * 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
AU5599594A (en) * 1992-11-16 1994-06-08 Ciba-Geigy Ag Polyvinyl alcohol/borate ophthalmic drug delivery system
US5494901A (en) * 1993-01-05 1996-02-27 Javitt; Jonathan C. Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
SE501482C2 (sv) * 1993-06-24 1995-02-27 Leiras Oy Komposition för topisk administration av bispilokarpinsyradiestrar till ögat i form av en vattenlösning
WO1995003784A1 (en) * 1993-07-28 1995-02-09 Insite Vision Incorporated Suspensions for delivery of medicament
WO1996001558A1 (en) * 1994-07-11 1996-01-25 Pate David W Anandamide analogue compositions and method of treating intraocular hypertention using same
US5631297A (en) * 1994-07-11 1997-05-20 Pate; David W. Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same
JP3297969B2 (ja) * 1994-12-26 2002-07-02 ライオン株式会社 点眼剤
KR100261585B1 (ko) * 1995-01-20 2000-07-15 오쿠다 기요아키 항염증점안제
CA2210749C (en) * 1995-01-20 2001-04-10 Wakamoto Pharmaceutical Co., Ltd. Anti-inflammatory eye drop
US6476004B1 (en) 1996-07-18 2002-11-05 Mitsubishi Pharma Corporation Pharmaceutical composition
JP2002241272A (ja) * 1996-07-18 2002-08-28 Mitsubishi Pharma Corp 医薬処方組成物
JPH11209277A (ja) * 1998-01-19 1999-08-03 Yoshitomi Pharmaceut Ind Ltd 医薬組成物
GB9711643D0 (en) * 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
JP2002523475A (ja) * 1998-09-02 2002-07-30 アラーガン・セイルズ・インコーポレイテッド 防腐したシクロデキストリン含有組成物
JP2001125052A (ja) * 1999-10-25 2001-05-11 Lion Corp コンタクトレンズ装着液
EP1312380B1 (en) * 2000-06-19 2006-05-03 Santen Pharmaceutical Co., Ltd. Aseptics
US6468989B1 (en) 2000-07-13 2002-10-22 Dow Pharmaceutical Sciences Gel compositions containing metronidazole
US6881726B2 (en) 2001-12-24 2005-04-19 Dow Pharmaceutical Sciences Aqueous compositions containing metronidazole
WO2006137433A1 (ja) * 2005-06-21 2006-12-28 Wakamoto Pharmaceutical Co., Ltd. レボカバスチンを可溶化させた水性薬剤
US20100069335A1 (en) * 2005-07-15 2010-03-18 Rajiv Bhushan Prevention and Treatment of Ophthalmic Complications of Diabetes
KR101875845B1 (ko) 2012-03-26 2018-07-06 산텐 세이야꾸 가부시키가이샤 디쿠아포솔 함유 점안액
CN112272578A (zh) * 2018-04-27 2021-01-26 阿勒根公司 抗微生物功效增强且毒性降低的亚氯酸钠组合物
EP4052694A4 (en) * 2019-11-21 2023-09-20 Samjin Pharmaceutical Co., Ltd. EYE DROPS COMPOSITION FOR PREVENTING OR TREATING EYE DISEASES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU602641B2 (en) * 1986-04-17 1990-10-18 Senju Pharmaceutical Co., Ltd. Thiolactam-N-acetic acid derivatives, their production and use

Also Published As

Publication number Publication date
RU2068260C1 (ru) 1996-10-27
JPH05213757A (ja) 1993-08-24
DE69109021D1 (de) 1995-05-24
KR920003971A (ko) 1992-03-27
FI97777B (fi) 1996-11-15
ATE121295T1 (de) 1995-05-15
HU207950B (en) 1993-07-28
NO913136L (no) 1992-02-14
FI913811A (fi) 1992-02-14
HU912692D0 (en) 1992-01-28
HUT61196A (en) 1992-12-28
NO177845B (no) 1995-08-28
EP0472327A1 (en) 1992-02-26
US5663170A (en) 1997-09-02
TW200402B (pt) 1993-02-21
AU8170891A (en) 1992-02-20
NO913136D0 (no) 1991-08-12
JP2769253B2 (ja) 1998-06-25
FI97777C (fi) 1997-02-25
PT98643B (pt) 1999-01-29
AU633754B2 (en) 1993-02-04
CA2048942A1 (en) 1992-02-14
DK0472327T3 (da) 1995-05-08
ES2071227T3 (es) 1995-06-16
FI913811A0 (fi) 1991-08-12
EP0472327B1 (en) 1995-04-19
DE69109021T2 (de) 1995-09-21
NO177845C (no) 1995-12-06

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BB1A Laying open of patent application

Effective date: 19920327

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Effective date: 19981020

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Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000430