PT98366A - Processo para a preparacao de novos derivados de tiazolilo substituido e de pitidinilo substituido e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de novos derivados de tiazolilo substituido e de pitidinilo substituido e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT98366A PT98366A PT98366A PT9836691A PT98366A PT 98366 A PT98366 A PT 98366A PT 98366 A PT98366 A PT 98366A PT 9836691 A PT9836691 A PT 9836691A PT 98366 A PT98366 A PT 98366A
- Authority
- PT
- Portugal
- Prior art keywords
- substituted
- formula
- alk
- pydidinyl
- contain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55432590A | 1990-07-19 | 1990-07-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT98366A true PT98366A (pt) | 1992-05-29 |
| PT98366B PT98366B (pt) | 1999-01-29 |
Family
ID=24212925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT98366A PT98366B (pt) | 1990-07-19 | 1991-07-18 | Processo para a preparacao de novos derivados de tiazolilo substituido e de pitidinilo substituido e de composicoes farmaceuticas que os contem |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0539420B1 (pt) |
| JP (1) | JP3085707B2 (pt) |
| KR (1) | KR100206723B1 (pt) |
| CN (1) | CN1037770C (pt) |
| AT (1) | ATE188477T1 (pt) |
| AU (1) | AU646280B2 (pt) |
| CA (1) | CA2086546A1 (pt) |
| CZ (1) | CZ279903B6 (pt) |
| DE (1) | DE69131895T2 (pt) |
| DK (1) | DK0539420T3 (pt) |
| ES (1) | ES2142802T3 (pt) |
| FI (1) | FI102753B1 (pt) |
| GR (1) | GR3032999T3 (pt) |
| HU (1) | HU221298B1 (pt) |
| IE (1) | IE912533A1 (pt) |
| IL (1) | IL98865A (pt) |
| MX (1) | MX9100307A (pt) |
| NO (1) | NO304791B1 (pt) |
| NZ (1) | NZ238863A (pt) |
| PH (1) | PH31063A (pt) |
| PL (1) | PL170580B1 (pt) |
| PT (1) | PT98366B (pt) |
| RU (1) | RU2067978C1 (pt) |
| SK (1) | SK280690B6 (pt) |
| TW (1) | TW209217B (pt) |
| WO (1) | WO1992001697A1 (pt) |
| ZA (1) | ZA915654B (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2048109B1 (es) * | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
| US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
| US5998439A (en) * | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
| US5922737A (en) * | 1996-02-21 | 1999-07-13 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases |
| TR200500707T2 (tr) | 1999-06-28 | 2005-04-21 | Janssen Pharmaceutica N.V. | Solunum sistemi sinsitiyal virüsünün replikasyonunu inhibe edici maddeler. |
| SI1196408T1 (en) * | 1999-06-28 | 2005-02-28 | Janssen Pharmaceutica N.V. | Respiratory syncytial virus replication inhibitors |
| CN1210275C (zh) * | 1999-06-28 | 2005-07-13 | 詹森药业有限公司 | 呼吸道合胞病毒复制抑制剂 |
| DK1599468T3 (da) | 2003-01-14 | 2008-02-04 | Arena Pharm Inc | 1,2,3-trisubstituerede aryl- og heteroarylderivater som modulatorer af metabolisme og forebyggelse og behandling af forstyrrelser forbundet dermed såsom diabetes og hyperglykæmi |
| AR045047A1 (es) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos |
| WO2005113511A1 (en) * | 2004-05-12 | 2005-12-01 | Bristol-Myers Squibb Company | Urea antagonists of p2y1 receptor useful in the treatment of thrombotic conditions |
| DOP2006000010A (es) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | Procedimiento para preparar eteres aromáticos |
| US10894787B2 (en) | 2010-09-22 | 2021-01-19 | Arena Pharmaceuticals, Inc. | Modulators of the GPR119 receptor and the treatment of disorders related thereto |
| EP3040334A1 (en) | 2014-12-29 | 2016-07-06 | Faes Farma, S.A. | New benzimidazole derivatives as antihistamine agents |
| WO2016112075A1 (en) | 2015-01-06 | 2016-07-14 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
| SI3310760T1 (sl) | 2015-06-22 | 2023-02-28 | Arena Pharmaceuticals, Inc. | Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| US4695569A (en) * | 1983-11-30 | 1987-09-22 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines |
| US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
| US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
| GB8515934D0 (en) * | 1985-06-24 | 1985-07-24 | Janssen Pharmaceutica Nv | (4-piperidinomethyl and-hetero)purines |
| US4835161A (en) * | 1986-02-03 | 1989-05-30 | Janssen Pharmaceutica N.V. | Anti-histaminic compositions containing n-heterocyclyl-4-piperidinamines |
| DE3701863A1 (de) * | 1987-01-23 | 1988-08-04 | Standard Elektrik Lorenz Ag | Sender zur kohaerent optischen nachrichtenuebertragung |
| US4897401A (en) * | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
| CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
| GB8900380D0 (en) * | 1989-01-09 | 1989-03-08 | Janssen Pharmaceutica Nv | 2-aminopyrimidinone derivatives |
-
1991
- 1991-07-05 NZ NZ238863A patent/NZ238863A/xx unknown
- 1991-07-09 JP JP03511645A patent/JP3085707B2/ja not_active Expired - Fee Related
- 1991-07-09 RU RU9192016595A patent/RU2067978C1/ru not_active IP Right Cessation
- 1991-07-09 HU HU9300096A patent/HU221298B1/hu not_active IP Right Cessation
- 1991-07-09 AT AT91912667T patent/ATE188477T1/de not_active IP Right Cessation
- 1991-07-09 ES ES91912667T patent/ES2142802T3/es not_active Expired - Lifetime
- 1991-07-09 CA CA002086546A patent/CA2086546A1/en not_active Abandoned
- 1991-07-09 PL PL91297612A patent/PL170580B1/pl not_active IP Right Cessation
- 1991-07-09 DK DK91912667T patent/DK0539420T3/da active
- 1991-07-09 AU AU82093/91A patent/AU646280B2/en not_active Ceased
- 1991-07-09 EP EP91912667A patent/EP0539420B1/en not_active Expired - Lifetime
- 1991-07-09 DE DE69131895T patent/DE69131895T2/de not_active Expired - Fee Related
- 1991-07-09 WO PCT/EP1991/001292 patent/WO1992001697A1/en active IP Right Grant
- 1991-07-09 KR KR1019930700122A patent/KR100206723B1/ko not_active IP Right Cessation
- 1991-07-11 PH PH42771A patent/PH31063A/en unknown
- 1991-07-17 IL IL9886591A patent/IL98865A/en not_active IP Right Cessation
- 1991-07-18 CZ CS912239A patent/CZ279903B6/cs not_active IP Right Cessation
- 1991-07-18 PT PT98366A patent/PT98366B/pt not_active IP Right Cessation
- 1991-07-18 IE IE253391A patent/IE912533A1/en not_active Application Discontinuation
- 1991-07-18 SK SK2239-91A patent/SK280690B6/sk unknown
- 1991-07-18 ZA ZA915654A patent/ZA915654B/xx unknown
- 1991-07-19 CN CN91104906A patent/CN1037770C/zh not_active Expired - Fee Related
- 1991-07-19 MX MX9100307A patent/MX9100307A/es not_active IP Right Cessation
- 1991-08-03 TW TW080106084A patent/TW209217B/zh active
-
1993
- 1993-01-15 NO NO924313A patent/NO304791B1/no unknown
- 1993-01-18 FI FI930199A patent/FI102753B1/fi active
-
2000
- 2000-03-21 GR GR20000400699T patent/GR3032999T3/el not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT98366A (pt) | Processo para a preparacao de novos derivados de tiazolilo substituido e de pitidinilo substituido e de composicoes farmaceuticas que os contem | |
| DE3882556T2 (de) | 1-Alkyl-substituierte Benzimidazolderivate. | |
| DK0378254T3 (da) | 2-aminopyrimidinonderivater | |
| PT93671A (pt) | Processo para a preparacao de derivados de hidroxi-alquil-furanilo e de composicoes farmaceuticas que os contem | |
| SE8205523D0 (sv) | Antranilsyraestrar, forfarande for framstellning derav och farmaceutiska kompositioner som innehaller dem |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920117 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19981015 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20050415 |