PT971713E - Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao - Google Patents

Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao

Info

Publication number
PT971713E
PT971713E PT98905121T PT98905121T PT971713E PT 971713 E PT971713 E PT 971713E PT 98905121 T PT98905121 T PT 98905121T PT 98905121 T PT98905121 T PT 98905121T PT 971713 E PT971713 E PT 971713E
Authority
PT
Portugal
Prior art keywords
disorders
colinesterase
atention
inhibitors
treatment
Prior art date
Application number
PT98905121T
Other languages
English (en)
Portuguese (pt)
Inventor
Sharon L Rogers
Lawrence T Friedhoff
Paul J Tiseo
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of PT971713E publication Critical patent/PT971713E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT98905121T 1997-03-03 1998-03-03 Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao PT971713E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3983297P 1997-03-03 1997-03-03

Publications (1)

Publication Number Publication Date
PT971713E true PT971713E (pt) 2003-09-30

Family

ID=21907565

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98905121T PT971713E (pt) 1997-03-03 1998-03-03 Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao

Country Status (12)

Country Link
US (2) US6455544B1 (https=)
EP (1) EP0971713B1 (https=)
JP (1) JP4095676B2 (https=)
AT (1) ATE241358T1 (https=)
AU (1) AU743609B2 (https=)
CA (1) CA2282654C (https=)
DE (1) DE69815090T2 (https=)
DK (1) DK0971713T3 (https=)
ES (1) ES2200313T3 (https=)
NZ (1) NZ337515A (https=)
PT (1) PT971713E (https=)
WO (1) WO1998039000A1 (https=)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0971713B1 (en) * 1997-03-03 2003-05-28 Eisai Co., Ltd. Use of cholinesterase inhibitors to treat disorders of attention
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
US6429207B1 (en) 1997-11-21 2002-08-06 Nps Pharmaceuticals, Inc. Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
US20030153598A1 (en) * 2000-07-25 2003-08-14 Raymond Pratt Methods for treating Parkinson's disease with cholinesterase inhibitors
EP1311272B1 (en) 2000-03-03 2006-11-22 Eisai Co., Ltd. Novel methods using cholinesterase inhibitors
EP1764101A1 (en) * 2000-03-03 2007-03-21 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments
JP2006516948A (ja) * 2000-11-14 2006-07-13 ニュー リバー ファーマシューティカルズ インコーポレイテッド 硫酸アバカビルを含有する新規な薬剤化合物および同化合物の製造ならびに使用方法
WO2004034963A2 (en) * 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
US20070053976A1 (en) * 2002-05-17 2007-03-08 Eisai R & D Management Co., Ltd. Novel combination of drugs as antidepressant
US7589199B2 (en) 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
DK1531822T3 (da) 2002-06-12 2009-12-07 Chemocentryx Inc 1-aryl-4-substituerede piperazin derivater til anvendelse som CCR1 antagonister til behandlingen af inflammation og immunforstyrrelser
US7842693B2 (en) 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
WO2005065645A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Donepezil formulations
US7435830B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7435831B2 (en) 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
JP4696062B2 (ja) * 2004-04-28 2011-06-08 エーザイ・アール・アンド・ディー・マネジメント株式会社 1−ベンジル−4−[(5,6−ジメトキシ−1−インダノン)−2−イル]メチルピペリジンおよびその塩酸塩の製造法
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
US20060079558A1 (en) * 2004-09-27 2006-04-13 Bridge Pharma. Inc. R-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine and other dermal anesthetics
CA2589102C (en) 2004-11-02 2013-08-13 Northwestern University Pyridazine compounds and methods for using the compounds to treat inflammatory diseases
WO2006081332A1 (en) * 2005-01-25 2006-08-03 Epix Delaware, Inc. Substituted arylamine compounds and their use as 5-ht6 modulators
US20060270709A1 (en) * 2005-04-04 2006-11-30 Eisai Co. Ltd. Dihydropyridine compounds and compositions for headaches
CA2624805A1 (en) * 2005-10-14 2007-04-19 Eisai R&D Management Co., Ltd. Process for producing 1-benzyl-4-[(5,6-dimethoxy-1­indanon)-2-yl]methylpiperidine or hydrochloride thereof
CN101410374A (zh) * 2005-11-14 2009-04-15 麦迪凯姆股份公司 用于制备盐酸多奈哌齐的中间体和其新多晶型物的改良的合成和制备
CA2650711A1 (en) 2006-04-28 2007-11-08 Northwestern University Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
US7592458B2 (en) * 2006-07-21 2009-09-22 Wright George E Dermal anesthetic compounds and pharmaceutical compositions for inducing local anesthesia and mitigating neuropathic pain
US20100048628A1 (en) * 2006-12-01 2010-02-25 Sumiyo Nishi Method for suppressing discoloration over time of adhesive preparation containing donepezil
JP5237112B2 (ja) * 2006-12-01 2013-07-17 日東電工株式会社 経皮吸収製剤
US20100099714A1 (en) * 2007-03-05 2010-04-22 Eisai R&D Management Co., Ltd. AMPA and NMDA Receptor Antagonists for Neurodegenerative Diseases
EP2148673A1 (en) * 2007-04-26 2010-02-03 Eisai R&D Management Co., Ltd. Cinnamide compounds for dementia
KR100914691B1 (ko) * 2007-08-10 2009-08-28 주식회사유한양행 도네페질 또는 그의 제조용 중간체의 제조방법
KR20110020788A (ko) * 2008-05-30 2011-03-03 에자이 알앤드디 매니지먼트 가부시키가이샤 경피 흡수 제제
WO2009145177A1 (ja) * 2008-05-30 2009-12-03 日東電工株式会社 ドネペジル含有貼付製剤およびその包装体
EA202092673A3 (ru) 2010-02-09 2021-05-31 Дзе Джонс Хопкинс Юниверсити Способы и композиции для улучшения когнитивной функции
WO2012071369A2 (en) 2010-11-24 2012-05-31 The Trustees Of Columbia University In The City Of New York A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
WO2013166037A1 (en) 2012-05-01 2013-11-07 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of eye disorders
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
US9944644B2 (en) 2013-03-14 2018-04-17 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles their preparation and use
US9637450B2 (en) 2013-03-14 2017-05-02 The Trustees Of Columbia University In The City Of New York Octahydrocyclopentapyrroles, their preparation and use
US9938291B2 (en) 2013-03-14 2018-04-10 The Trustess Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
EP2968304B1 (en) 2013-03-14 2018-10-10 The Trustees of Columbia University in the City of New York 4-phenylpiperidines, their preparation and use
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
EP4036094B1 (en) 2014-04-30 2025-12-24 The Trustees of Columbia University in the City of New York Substituted 4-phenylpiperidines, their preparation and use
KR101732776B1 (ko) * 2014-10-08 2017-05-04 영남대학교 산학협력단 신규한 인데노 피리디니움 유도체 화합물 및 이의 제조방법
CA2986598C (en) 2015-05-22 2023-09-26 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US5064858A (en) * 1988-08-17 1991-11-12 Spectrum Pharmaceutical Corporation Protected complex of procaine for the treatment of symptoms from narcotics addiction, tinnitus and Alzheimer's disease
WO1997003671A1 (en) * 1995-07-14 1997-02-06 Medeva Europe Limited Composition comprising d-threo-methylphenidate and another drug
SI9720038B (sl) * 1996-06-07 2010-06-30 Eisai Co Ltd Polimorfi donepezil hidroklorida in postopek izdelave
EP0971713B1 (en) * 1997-03-03 2003-05-28 Eisai Co., Ltd. Use of cholinesterase inhibitors to treat disorders of attention

Also Published As

Publication number Publication date
US7105540B2 (en) 2006-09-12
JP2001515480A (ja) 2001-09-18
DE69815090T2 (de) 2004-02-19
NZ337515A (en) 2002-07-26
US6455544B1 (en) 2002-09-24
EP0971713A1 (en) 2000-01-19
DK0971713T3 (da) 2003-09-22
WO1998039000A1 (en) 1998-09-11
JP4095676B2 (ja) 2008-06-04
EP0971713B1 (en) 2003-05-28
CA2282654A1 (en) 1998-09-11
ATE241358T1 (de) 2003-06-15
DE69815090D1 (de) 2003-07-03
ES2200313T3 (es) 2004-03-01
CA2282654C (en) 2009-02-03
AU7321598A (en) 1998-09-22
AU743609B2 (en) 2002-01-31
US20030055040A1 (en) 2003-03-20

Similar Documents

Publication Publication Date Title
PT971713E (pt) Utilizacao de inibidores da colinesterase para tratamento de desordens da atencao
TR200102499T2 (tr) Neoplazi tedavisinde bir kombinasyon terapisi olarak bir siklooksijenaz-2 inhibitörü ve bir veya daha fazla antineoplastik ajan kullanma yöntemi
TR200200204T2 (tr) MEK inhibitörleri kullanılarak kronik ağrının tedavi edilmesi.
DE69924641D1 (de) Behandlung von asthma anhand von mek-inhibitoren
TR200000755T2 (tr) Karşıt olma-karşı gelme bozukluğunun tedavisi.
DE69805973D1 (de) Behandlung von herzrythmusstörungen durch hemmung einer multifunktionalen calcium/calmodulin-abhängigen protein kinase
SE9803710D0 (sv) Use of certain drugs for treating nerve root injury
NO996578L (no) Urokinase-inhibitorer
DK0840606T3 (da) Små di- og trivalente molekyler som selectininhibitorer
PT946166E (pt) Utilizacao de inibidores das metaloproteinases da matriz para tratar disturbios neurologicos e promover a cicatrizacao de feridas
ES2104358T3 (es) Inhibidores sililados de acetilcolinesterasa.
PT1051187E (pt) Tratamento de linfomas foliculares usando inibidores da via da linfotoxina (lt)
AP9801261A0 (en) Farnesyl transferase inhibitors in combination with HMG COA reductase inhibitors for the treatment of cancer.
PT888330E (pt) Metodos de tratamento ou prevencao de cistite intersticial
ATE322898T1 (de) Inhibitoren von mycobakterien
AU2002347984A1 (en) Use of norepinephrine reuptake inhibitors for the treatment of tic disorders
EE9700350A (et) COMT-inhibiitorite uus kasutamine ja diabeetiliste vaskulaarsete häirete ärahoidmise meetod
MXPA02004699A (es) Derivados de acidos hidroxieicosatetraenoico modificados con cadena omega y metodos de su uso para el tratameinto del ojo reseco.
ID27052A (id) Pengobatan arthritis dan keadaan-keadaan lain yang sekupa
ES2180643T3 (es) Procedimiento para tratar la disfuncion cognitiva.
BR9708037A (pt) Método para o tratamento de abuso de substância
BR9612549A (pt) Método para tratamento de agressão excessiva
BR0314364A (pt) Uso de inibidores de pde iv para tratar angiogênese
AU2003282035A1 (en) Modulation of s6 kinase activity for the treatment of obestiy
NO984190L (no) FremgangsmÕte for behandling av insomnia