PT96017A - Processo para a preparacao de hexahidro-1h-quino{4,3,2-ef}{1,4}benzoxazeinas e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de hexahidro-1h-quino{4,3,2-ef}{1,4}benzoxazeinas e de composicoes farmaceuticas que os contem

Info

Publication number
PT96017A
PT96017A PT96017A PT9601790A PT96017A PT 96017 A PT96017 A PT 96017A PT 96017 A PT96017 A PT 96017A PT 9601790 A PT9601790 A PT 9601790A PT 96017 A PT96017 A PT 96017A
Authority
PT
Portugal
Prior art keywords
quino
preparation
chem
alkyl
formula
Prior art date
Application number
PT96017A
Other languages
English (en)
Other versions
PT96017B (pt
Inventor
Gregory Michael Shutske
Kevin James Kapples
John Dick Tomer
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT96017A publication Critical patent/PT96017A/pt
Publication of PT96017B publication Critical patent/PT96017B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
PT96017A 1989-11-28 1990-11-28 Processo para a preparacao de hexahidro-1h-quino{4,3,2-ef}{1,4}benzoxazeinas e de composicoes farmaceuticas que os contem PT96017B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/443,288 US4994452A (en) 1989-11-28 1989-11-28 Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds

Publications (2)

Publication Number Publication Date
PT96017A true PT96017A (pt) 1991-09-13
PT96017B PT96017B (pt) 1998-02-27

Family

ID=23760195

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96017A PT96017B (pt) 1989-11-28 1990-11-28 Processo para a preparacao de hexahidro-1h-quino{4,3,2-ef}{1,4}benzoxazeinas e de composicoes farmaceuticas que os contem

Country Status (21)

Country Link
US (1) US4994452A (pt)
EP (1) EP0430114B1 (pt)
JP (1) JP2600019B2 (pt)
KR (1) KR100190782B1 (pt)
AT (1) ATE133953T1 (pt)
AU (2) AU633382B2 (pt)
CA (1) CA2030715C (pt)
CZ (1) CZ283943B6 (pt)
DE (1) DE69025274T2 (pt)
DK (1) DK0430114T3 (pt)
ES (1) ES2083416T3 (pt)
FI (1) FI905813A (pt)
GR (1) GR3019089T3 (pt)
HU (1) HU207326B (pt)
IE (1) IE72154B1 (pt)
IL (1) IL96467A (pt)
NO (1) NO905128L (pt)
PL (1) PL287958A1 (pt)
PT (1) PT96017B (pt)
YU (1) YU224890A (pt)
ZA (1) ZA909513B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10004572A1 (de) * 2000-02-02 2001-08-09 Boehringer Ingelheim Pharma Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3232945A (en) * 1962-08-13 1966-02-01 S E Massengill Company 7,8,9,10-tetrahalo-6h-cyclohepta-(b)-quinolines
US3318896A (en) * 1963-12-05 1967-05-09 Squibb & Sons Inc Production of 12-substituted-6, 7, 8, 9, 10, 11-hexahydrocycloocta[b]quinolines
US3329676A (en) * 1964-11-09 1967-07-04 American Home Prod Fused 1, 4-diazepine ring systems
US3580915A (en) * 1968-09-16 1971-05-25 American Home Prod 1,2,3,4-tetrahydrobenzol(b)(1,6)naphthyridine derivatives
ES431307A1 (es) * 1973-11-16 1976-09-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos derivados de quinoleina.
US4631286A (en) * 1984-10-25 1986-12-23 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US4695573A (en) * 1984-10-25 1987-09-22 Hoechst-Roussel Pharmaceuticals Inc. 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds
US4816456A (en) * 1986-10-01 1989-03-28 Summers William K Administration of monoamine acridines in cholinergic neuronal deficit states
DK569087A (da) * 1986-10-31 1988-05-01 Sumitomo Pharma Quinolin-derivater, deres fremstilling og anvendelse
FI91401C (fi) * 1987-03-17 1994-06-27 Hoechst Roussel Pharma Menetelmä terapeuttisesti aktiivisten substituoitujen 9-aminotetrahydroakriinien ja niille läheisten yhdisteiden valmistamiseksi
US4743601A (en) * 1987-07-13 1988-05-10 Hoechst-Roussel Pharmaceuticals Inc. Dihydro-1,4-oxazino(2,3-C)quinolines
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives
WO1989002739A1 (en) * 1987-10-05 1989-04-06 Pfizer Inc. 4-aminopyridine derivatives
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine

Also Published As

Publication number Publication date
JP2600019B2 (ja) 1997-04-16
EP0430114B1 (en) 1996-02-07
PT96017B (pt) 1998-02-27
HU207326B (en) 1993-03-29
ZA909513B (en) 1991-08-28
JPH03209383A (ja) 1991-09-12
CZ588790A3 (cs) 1998-02-18
FI905813A0 (fi) 1990-11-26
YU224890A (en) 1999-11-22
CA2030715C (en) 2003-02-11
AU6696290A (en) 1991-06-06
NO905128L (no) 1991-05-29
ES2083416T3 (es) 1996-04-16
IL96467A (en) 1999-08-17
IE72154B1 (en) 1997-03-26
DE69025274T2 (de) 1996-08-22
DE69025274D1 (de) 1996-03-21
HUT61026A (en) 1992-11-30
IE904279A1 (en) 1991-06-05
EP0430114A2 (en) 1991-06-05
PL287958A1 (en) 1992-08-24
AU2856092A (en) 1993-02-11
DK0430114T3 (da) 1996-06-17
NO905128D0 (no) 1990-11-27
EP0430114A3 (en) 1992-01-29
KR910009666A (ko) 1991-06-28
AU633382B2 (en) 1993-01-28
HU907667D0 (en) 1991-06-28
FI905813A (fi) 1991-05-29
US4994452A (en) 1991-02-19
ATE133953T1 (de) 1996-02-15
CA2030715A1 (en) 1991-05-29
GR3019089T3 (en) 1996-05-31
KR100190782B1 (ko) 1999-06-01
IL96467A0 (en) 1991-08-16
CZ283943B6 (cs) 1998-07-15

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910410

FG3A Patent granted, date of granting

Effective date: 19971106

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20070507