PT97637A - Processo para a preparacao de derivados piperidiloxi- e quinuclidiniloxi-isoxazolicos e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados piperidiloxi- e quinuclidiniloxi-isoxazolicos e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT97637A PT97637A PT97637A PT9763791A PT97637A PT 97637 A PT97637 A PT 97637A PT 97637 A PT97637 A PT 97637A PT 9763791 A PT9763791 A PT 9763791A PT 97637 A PT97637 A PT 97637A
- Authority
- PT
- Portugal
- Prior art keywords
- hydrogen
- quinuclidynyloxy
- isoxazolic
- piperidyloxy
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11975490 | 1990-05-11 | ||
JP21651990 | 1990-08-17 | ||
JP27848990 | 1990-10-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT97637A true PT97637A (pt) | 1992-02-28 |
PT97637B PT97637B (pt) | 1998-08-31 |
Family
ID=27313898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT97637A PT97637B (pt) | 1990-05-11 | 1991-05-10 | Processo para a preparacao de derivados piperidiloxi- e quinuclidiniloxi-isoxazolicos e de composicoes farmaceuticas que os contem |
Country Status (15)
Country | Link |
---|---|
US (1) | US5643923A (pt) |
EP (1) | EP0456519B1 (pt) |
JP (1) | JPH0747585B2 (pt) |
KR (1) | KR0178369B1 (pt) |
CN (1) | CN1042225C (pt) |
AT (1) | ATE108448T1 (pt) |
CA (1) | CA2042336A1 (pt) |
CZ (1) | CZ284343B6 (pt) |
DE (1) | DE69102816T2 (pt) |
DK (1) | DK0456519T3 (pt) |
ES (1) | ES2060303T3 (pt) |
HK (1) | HK1005728A1 (pt) |
HU (2) | HU215832B (pt) |
IE (1) | IE65997B1 (pt) |
PT (1) | PT97637B (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2074981T3 (es) * | 1986-12-17 | 1995-10-01 | Glaxo Group Ltd | Uso de derivados heterociclicos en el tratamiento de trastornos cognoscitivos. |
EP0492020A1 (en) * | 1990-12-21 | 1992-07-01 | Merrell Dow Pharmaceuticals Inc. | Use of certain esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and related compounds for treating cognitive disorders |
GB9226573D0 (en) * | 1992-12-21 | 1993-02-17 | Ici Plc | Heterocyclic compounds |
DK124393D0 (da) * | 1993-11-03 | 1993-11-03 | Lundbeck & Co As H | Compounds |
US5821370A (en) * | 1994-10-24 | 1998-10-13 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US6040442A (en) * | 1995-06-01 | 2000-03-21 | Eli Lilly And Company | Process for preparing 1,2,5-thiadiazole containing ethers |
RU2165415C2 (ru) * | 1996-02-27 | 2001-04-20 | Санкио Компани Лимитед | Производные изоксазола и фармацевтическая композиция на их основе |
UA52698C2 (uk) | 1996-10-04 | 2003-01-15 | Х. Луннбек А/С | Похідні (3-алкоксіізоксазол-4-іл)заміщеної 2-амінокарбонової кислоти та їх сірковмісні аналоги, фармацевтична композиція на їх основі |
EP1102755B1 (en) | 1998-08-07 | 2006-01-04 | Chiron Corporation | Substituted isoxazole derivatives as estrogen receptor modulators |
US7655657B2 (en) | 2003-12-22 | 2010-02-02 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
US7160876B2 (en) | 2003-12-22 | 2007-01-09 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
TWI471095B (zh) | 2009-12-21 | 2015-02-01 | Nippon Soda Co | 環胺化合物及殺蟎劑 |
AR081721A1 (es) * | 2010-02-25 | 2012-10-17 | Nippon Soda Co | Compuesto de amina ciclica y acaricida |
HU230649B1 (hu) | 2013-01-24 | 2017-05-29 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3290301A (en) * | 1963-12-02 | 1966-12-06 | Shionogi & Co | Certain 3-aminoalkyl-5-alkylisoxazoles |
AT254868B (de) * | 1964-02-13 | 1967-06-12 | Shionogi & Co | Verfahren zur Herstellung von neuen disubstituierten Isoxazolverbindungen |
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
ZA879631B (en) * | 1986-12-26 | 1989-08-30 | Sankyo Co | Centrally-acting muscle relaxants |
US5321037A (en) * | 1986-12-26 | 1994-06-14 | Sankyo Company, Limited | Isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants |
CA1307790C (en) * | 1987-08-04 | 1992-09-22 | Ian Anthony Cliffe | Ethers |
ES2057110T3 (es) * | 1988-03-24 | 1994-10-16 | Sankyo Co | Utilizacion de isoxazolinonas como farmacos con accion sobre el cerebro. |
IE62276B1 (en) * | 1988-03-30 | 1995-01-25 | Sankyo Co | "New isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants" |
US5116839A (en) * | 1989-06-26 | 1992-05-26 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
YU84791A (sh) * | 1990-05-19 | 1994-06-10 | Boehringer Ingelheim Kg. | Biciklicni 1-aza-cikloalkalni |
-
1991
- 1991-05-10 CZ CS911385A patent/CZ284343B6/cs not_active IP Right Cessation
- 1991-05-10 JP JP3105741A patent/JPH0747585B2/ja not_active Expired - Lifetime
- 1991-05-10 HU HU1568/91A patent/HU215832B/hu not_active IP Right Cessation
- 1991-05-10 CA CA002042336A patent/CA2042336A1/en not_active Abandoned
- 1991-05-10 PT PT97637A patent/PT97637B/pt not_active IP Right Cessation
- 1991-05-10 ES ES91304254T patent/ES2060303T3/es not_active Expired - Lifetime
- 1991-05-10 DE DE69102816T patent/DE69102816T2/de not_active Expired - Fee Related
- 1991-05-10 DK DK91304254.5T patent/DK0456519T3/da active
- 1991-05-10 EP EP91304254A patent/EP0456519B1/en not_active Expired - Lifetime
- 1991-05-10 IE IE159891A patent/IE65997B1/en unknown
- 1991-05-10 AT AT91304254T patent/ATE108448T1/de not_active IP Right Cessation
- 1991-05-11 CN CN91103768A patent/CN1042225C/zh not_active Expired - Fee Related
- 1991-05-11 KR KR1019910007621A patent/KR0178369B1/ko not_active IP Right Cessation
-
1992
- 1992-08-27 US US07/937,445 patent/US5643923A/en not_active Expired - Fee Related
-
1995
- 1995-06-29 HU HU95P/P00539P patent/HU211875A9/hu unknown
-
1998
- 1998-06-03 HK HK98104828A patent/HK1005728A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE911598A1 (en) | 1991-11-20 |
DE69102816T2 (de) | 1995-03-16 |
ES2060303T3 (es) | 1994-11-16 |
CN1042225C (zh) | 1999-02-24 |
CZ284343B6 (cs) | 1998-10-14 |
IE65997B1 (en) | 1995-11-29 |
HUT60735A (en) | 1992-10-28 |
ATE108448T1 (de) | 1994-07-15 |
EP0456519A1 (en) | 1991-11-13 |
PT97637B (pt) | 1998-08-31 |
DK0456519T3 (da) | 1994-11-07 |
DE69102816D1 (de) | 1994-08-18 |
HU911568D0 (en) | 1991-11-28 |
CA2042336A1 (en) | 1991-11-12 |
HU215832B (hu) | 1999-04-28 |
HU211875A9 (en) | 1995-12-28 |
CN1057259A (zh) | 1991-12-25 |
CS138591A3 (en) | 1992-03-18 |
KR0178369B1 (ko) | 1999-03-20 |
JPH04225977A (ja) | 1992-08-14 |
US5643923A (en) | 1997-07-01 |
KR910019988A (ko) | 1991-12-19 |
JPH0747585B2 (ja) | 1995-05-24 |
HK1005728A1 (en) | 1999-01-22 |
EP0456519B1 (en) | 1994-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19911022 |
|
FG3A | Patent granted, date of granting |
Effective date: 19980521 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19991130 |