ATE108448T1 - Piperdinyloxy- und chinindidinyloxy- isoxazol- derivate, ihre herstellung und ihre therapeutische verwendung. - Google Patents

Piperdinyloxy- und chinindidinyloxy- isoxazol- derivate, ihre herstellung und ihre therapeutische verwendung.

Info

Publication number
ATE108448T1
ATE108448T1 AT91304254T AT91304254T ATE108448T1 AT E108448 T1 ATE108448 T1 AT E108448T1 AT 91304254 T AT91304254 T AT 91304254T AT 91304254 T AT91304254 T AT 91304254T AT E108448 T1 ATE108448 T1 AT E108448T1
Authority
AT
Austria
Prior art keywords
hydrogen
quinindidinyloxy
piperdinyloxy
preparation
therapeutic use
Prior art date
Application number
AT91304254T
Other languages
English (en)
Inventor
Mitsuo C O Sankyo Compa Nagano
Junichi C O Sankyo Compa Sakai
Takeo C O Sankyo Com Kobayashi
Masao C O Sankyo Compan Kozuka
Nobuyoshi C O Sankyo Com Iwata
Yoshiko C O Sankyo Compan Kubo
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE108448T1 publication Critical patent/ATE108448T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
AT91304254T 1990-05-11 1991-05-10 Piperdinyloxy- und chinindidinyloxy- isoxazol- derivate, ihre herstellung und ihre therapeutische verwendung. ATE108448T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11975490 1990-05-11
JP21651990 1990-08-17
JP27848990 1990-10-17

Publications (1)

Publication Number Publication Date
ATE108448T1 true ATE108448T1 (de) 1994-07-15

Family

ID=27313898

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91304254T ATE108448T1 (de) 1990-05-11 1991-05-10 Piperdinyloxy- und chinindidinyloxy- isoxazol- derivate, ihre herstellung und ihre therapeutische verwendung.

Country Status (15)

Country Link
US (1) US5643923A (de)
EP (1) EP0456519B1 (de)
JP (1) JPH0747585B2 (de)
KR (1) KR0178369B1 (de)
CN (1) CN1042225C (de)
AT (1) ATE108448T1 (de)
CA (1) CA2042336A1 (de)
CZ (1) CZ284343B6 (de)
DE (1) DE69102816T2 (de)
DK (1) DK0456519T3 (de)
ES (1) ES2060303T3 (de)
HK (1) HK1005728A1 (de)
HU (2) HU215832B (de)
IE (1) IE65997B1 (de)
PT (1) PT97637B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3752062T2 (de) * 1986-12-17 1997-09-11 Glaxo Group Ltd Verwendung von heterozyklischen Derivaten zur Herstellung von Arzneimitteln
EP0492020A1 (de) * 1990-12-21 1992-07-01 Merrell Dow Pharmaceuticals Inc. Verwendung von bestimmten Estern von Hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-on und verwandter Verbindungen zur Behandlung von kognitiven Erkrankungen
GB9226573D0 (en) * 1992-12-21 1993-02-17 Ici Plc Heterocyclic compounds
DK124393D0 (da) * 1993-11-03 1993-11-03 Lundbeck & Co As H Compounds
US5672709A (en) * 1994-10-24 1997-09-30 Eli Lilly And Company Heterocyclic compounds and their preparation and use
US6040442A (en) * 1995-06-01 2000-03-21 Eli Lilly And Company Process for preparing 1,2,5-thiadiazole containing ethers
CA2247439A1 (en) * 1996-02-27 1997-09-04 Sankyo Company, Limited Isoxazole derivatives
UA52698C2 (uk) 1996-10-04 2003-01-15 Х. Луннбек А/С Похідні (3-алкоксіізоксазол-4-іл)заміщеної 2-амінокарбонової кислоти та їх сірковмісні аналоги, фармацевтична композиція на їх основі
ES2255294T3 (es) 1998-08-07 2006-06-16 Chiron Corporation Derivados de isoxazol sustituidos como moduladores del receptor de estrogenos.
US7655657B2 (en) 2003-12-22 2010-02-02 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US7160876B2 (en) 2003-12-22 2007-01-09 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
TWI471095B (zh) 2009-12-21 2015-02-01 Nippon Soda Co 環胺化合物及殺蟎劑
AR081721A1 (es) * 2010-02-25 2012-10-17 Nippon Soda Co Compuesto de amina ciclica y acaricida
HU230649B1 (hu) 2013-01-24 2017-05-29 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3290301A (en) * 1963-12-02 1966-12-06 Shionogi & Co Certain 3-aminoalkyl-5-alkylisoxazoles
AT254868B (de) * 1964-02-13 1967-06-12 Shionogi & Co Verfahren zur Herstellung von neuen disubstituierten Isoxazolverbindungen
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
ZA879631B (en) * 1986-12-26 1989-08-30 Sankyo Co Centrally-acting muscle relaxants
US5321037A (en) * 1986-12-26 1994-06-14 Sankyo Company, Limited Isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants
CA1307790C (en) * 1987-08-04 1992-09-22 Ian Anthony Cliffe Ethers
DE68915595T2 (de) * 1988-03-24 1994-09-15 Sankyo Co Verwendung von Isoxazolinonen als cerebro-aktive Medikamente.
IE62276B1 (en) * 1988-03-30 1995-01-25 Sankyo Co "New isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants"
US5116839A (en) * 1989-06-26 1992-05-26 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
YU84791A (sh) * 1990-05-19 1994-06-10 Boehringer Ingelheim Kg. Biciklicni 1-aza-cikloalkalni

Also Published As

Publication number Publication date
EP0456519A1 (de) 1991-11-13
DE69102816D1 (de) 1994-08-18
CZ284343B6 (cs) 1998-10-14
CN1042225C (zh) 1999-02-24
HUT60735A (en) 1992-10-28
PT97637B (pt) 1998-08-31
DE69102816T2 (de) 1995-03-16
IE911598A1 (en) 1991-11-20
HK1005728A1 (en) 1999-01-22
CN1057259A (zh) 1991-12-25
PT97637A (pt) 1992-02-28
EP0456519B1 (de) 1994-07-13
DK0456519T3 (da) 1994-11-07
HU211875A9 (en) 1995-12-28
KR910019988A (ko) 1991-12-19
HU215832B (hu) 1999-04-28
JPH04225977A (ja) 1992-08-14
CS138591A3 (en) 1992-03-18
CA2042336A1 (en) 1991-11-12
ES2060303T3 (es) 1994-11-16
JPH0747585B2 (ja) 1995-05-24
IE65997B1 (en) 1995-11-29
US5643923A (en) 1997-07-01
KR0178369B1 (ko) 1999-03-20
HU911568D0 (en) 1991-11-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee