DE69102816T2 - Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung. - Google Patents
Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung.Info
- Publication number
- DE69102816T2 DE69102816T2 DE69102816T DE69102816T DE69102816T2 DE 69102816 T2 DE69102816 T2 DE 69102816T2 DE 69102816 T DE69102816 T DE 69102816T DE 69102816 T DE69102816 T DE 69102816T DE 69102816 T2 DE69102816 T2 DE 69102816T2
- Authority
- DE
- Germany
- Prior art keywords
- hydrogen
- quininedidinyloxy
- piperdinyloxy
- preparation
- therapeutic use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11975490 | 1990-05-11 | ||
JP21651990 | 1990-08-17 | ||
JP27848990 | 1990-10-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69102816D1 DE69102816D1 (de) | 1994-08-18 |
DE69102816T2 true DE69102816T2 (de) | 1995-03-16 |
Family
ID=27313898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69102816T Expired - Fee Related DE69102816T2 (de) | 1990-05-11 | 1991-05-10 | Piperdinyloxy- und Chinindidinyloxy- isoxazol- Derivate, ihre Herstellung und ihre therapeutische Verwendung. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5643923A (de) |
EP (1) | EP0456519B1 (de) |
JP (1) | JPH0747585B2 (de) |
KR (1) | KR0178369B1 (de) |
CN (1) | CN1042225C (de) |
AT (1) | ATE108448T1 (de) |
CA (1) | CA2042336A1 (de) |
CZ (1) | CZ284343B6 (de) |
DE (1) | DE69102816T2 (de) |
DK (1) | DK0456519T3 (de) |
ES (1) | ES2060303T3 (de) |
HK (1) | HK1005728A1 (de) |
HU (2) | HU215832B (de) |
IE (1) | IE65997B1 (de) |
PT (1) | PT97637B (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3752062T2 (de) * | 1986-12-17 | 1997-09-11 | Glaxo Group Ltd | Verwendung von heterozyklischen Derivaten zur Herstellung von Arzneimitteln |
EP0492020A1 (de) * | 1990-12-21 | 1992-07-01 | Merrell Dow Pharmaceuticals Inc. | Verwendung von bestimmten Estern von Hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-on und verwandter Verbindungen zur Behandlung von kognitiven Erkrankungen |
GB9226573D0 (en) * | 1992-12-21 | 1993-02-17 | Ici Plc | Heterocyclic compounds |
DK124393D0 (da) * | 1993-11-03 | 1993-11-03 | Lundbeck & Co As H | Compounds |
US5672709A (en) * | 1994-10-24 | 1997-09-30 | Eli Lilly And Company | Heterocyclic compounds and their preparation and use |
US6040442A (en) * | 1995-06-01 | 2000-03-21 | Eli Lilly And Company | Process for preparing 1,2,5-thiadiazole containing ethers |
CA2247439A1 (en) * | 1996-02-27 | 1997-09-04 | Sankyo Company, Limited | Isoxazole derivatives |
UA52698C2 (uk) | 1996-10-04 | 2003-01-15 | Х. Луннбек А/С | Похідні (3-алкоксіізоксазол-4-іл)заміщеної 2-амінокарбонової кислоти та їх сірковмісні аналоги, фармацевтична композиція на їх основі |
ES2255294T3 (es) | 1998-08-07 | 2006-06-16 | Chiron Corporation | Derivados de isoxazol sustituidos como moduladores del receptor de estrogenos. |
US7655657B2 (en) | 2003-12-22 | 2010-02-02 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
US7160876B2 (en) | 2003-12-22 | 2007-01-09 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
TWI471095B (zh) | 2009-12-21 | 2015-02-01 | Nippon Soda Co | 環胺化合物及殺蟎劑 |
AR081721A1 (es) * | 2010-02-25 | 2012-10-17 | Nippon Soda Co | Compuesto de amina ciclica y acaricida |
HU230649B1 (hu) | 2013-01-24 | 2017-05-29 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Javított eljárás prasugrel gyógyszeripari hatóanyag és az 1-ciklopropil-2-(2-fluorofenil)-etanon intermedier előállítására |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3290301A (en) * | 1963-12-02 | 1966-12-06 | Shionogi & Co | Certain 3-aminoalkyl-5-alkylisoxazoles |
AT254868B (de) * | 1964-02-13 | 1967-06-12 | Shionogi & Co | Verfahren zur Herstellung von neuen disubstituierten Isoxazolverbindungen |
NZ219646A (en) * | 1986-03-27 | 1990-10-26 | Merck Sharp & Dohme | Oxadiazole derivatives of azacyclics for treating cns disorders |
ZA879631B (en) * | 1986-12-26 | 1989-08-30 | Sankyo Co | Centrally-acting muscle relaxants |
US5321037A (en) * | 1986-12-26 | 1994-06-14 | Sankyo Company, Limited | Isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants |
CA1307790C (en) * | 1987-08-04 | 1992-09-22 | Ian Anthony Cliffe | Ethers |
DE68915595T2 (de) * | 1988-03-24 | 1994-09-15 | Sankyo Co | Verwendung von Isoxazolinonen als cerebro-aktive Medikamente. |
IE62276B1 (en) * | 1988-03-30 | 1995-01-25 | Sankyo Co | "New isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants" |
US5116839A (en) * | 1989-06-26 | 1992-05-26 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
YU84791A (sh) * | 1990-05-19 | 1994-06-10 | Boehringer Ingelheim Kg. | Biciklicni 1-aza-cikloalkalni |
-
1991
- 1991-05-10 HU HU1568/91A patent/HU215832B/hu not_active IP Right Cessation
- 1991-05-10 JP JP3105741A patent/JPH0747585B2/ja not_active Expired - Lifetime
- 1991-05-10 ES ES91304254T patent/ES2060303T3/es not_active Expired - Lifetime
- 1991-05-10 CA CA002042336A patent/CA2042336A1/en not_active Abandoned
- 1991-05-10 EP EP91304254A patent/EP0456519B1/de not_active Expired - Lifetime
- 1991-05-10 CZ CS911385A patent/CZ284343B6/cs not_active IP Right Cessation
- 1991-05-10 AT AT91304254T patent/ATE108448T1/de not_active IP Right Cessation
- 1991-05-10 PT PT97637A patent/PT97637B/pt not_active IP Right Cessation
- 1991-05-10 DK DK91304254.5T patent/DK0456519T3/da active
- 1991-05-10 DE DE69102816T patent/DE69102816T2/de not_active Expired - Fee Related
- 1991-05-10 IE IE159891A patent/IE65997B1/en unknown
- 1991-05-11 KR KR1019910007621A patent/KR0178369B1/ko not_active IP Right Cessation
- 1991-05-11 CN CN91103768A patent/CN1042225C/zh not_active Expired - Fee Related
-
1992
- 1992-08-27 US US07/937,445 patent/US5643923A/en not_active Expired - Fee Related
-
1995
- 1995-06-29 HU HU95P/P00539P patent/HU211875A9/hu unknown
-
1998
- 1998-06-03 HK HK98104828A patent/HK1005728A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0456519A1 (de) | 1991-11-13 |
DE69102816D1 (de) | 1994-08-18 |
CZ284343B6 (cs) | 1998-10-14 |
CN1042225C (zh) | 1999-02-24 |
HUT60735A (en) | 1992-10-28 |
PT97637B (pt) | 1998-08-31 |
IE911598A1 (en) | 1991-11-20 |
HK1005728A1 (en) | 1999-01-22 |
CN1057259A (zh) | 1991-12-25 |
PT97637A (pt) | 1992-02-28 |
EP0456519B1 (de) | 1994-07-13 |
DK0456519T3 (da) | 1994-11-07 |
HU211875A9 (en) | 1995-12-28 |
ATE108448T1 (de) | 1994-07-15 |
KR910019988A (ko) | 1991-12-19 |
HU215832B (hu) | 1999-04-28 |
JPH04225977A (ja) | 1992-08-14 |
CS138591A3 (en) | 1992-03-18 |
CA2042336A1 (en) | 1991-11-12 |
ES2060303T3 (es) | 1994-11-16 |
JPH0747585B2 (ja) | 1995-05-24 |
IE65997B1 (en) | 1995-11-29 |
US5643923A (en) | 1997-07-01 |
KR0178369B1 (ko) | 1999-03-20 |
HU911568D0 (en) | 1991-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |