PT98911A - Processo para a preparacao de 3-(1h-indazol-3-il)-4-piridinaminas, seus intermediarios e composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de 3-(1h-indazol-3-il)-4-piridinaminas, seus intermediarios e composicoes farmaceuticas que os contem

Info

Publication number
PT98911A
PT98911A PT98911A PT9891191A PT98911A PT 98911 A PT98911 A PT 98911A PT 98911 A PT98911 A PT 98911A PT 9891191 A PT9891191 A PT 9891191A PT 98911 A PT98911 A PT 98911A
Authority
PT
Portugal
Prior art keywords
hydrogen
indazol
loweralkyl
pyridinamins
intermediaries
Prior art date
Application number
PT98911A
Other languages
English (en)
Other versions
PT98911B (pt
Inventor
Richard Charles Effland
Joseph Thomas Klein
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT98911A publication Critical patent/PT98911A/pt
Publication of PT98911B publication Critical patent/PT98911B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT98911A 1990-09-10 1991-09-09 Processo para a preparacao de 3-(1h-indazol-3-il)-4-piridinaminas, seus intermediarios e composicoes farmaceuticas que os contem PT98911B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/579,751 US5051430A (en) 1990-09-10 1990-09-10 3-(1H-indazol-3-yl)-4-pyridinamines

Publications (2)

Publication Number Publication Date
PT98911A true PT98911A (pt) 1992-07-31
PT98911B PT98911B (pt) 1999-02-26

Family

ID=24318208

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98911A PT98911B (pt) 1990-09-10 1991-09-09 Processo para a preparacao de 3-(1h-indazol-3-il)-4-piridinaminas, seus intermediarios e composicoes farmaceuticas que os contem

Country Status (20)

Country Link
US (1) US5051430A (pt)
EP (1) EP0475352B1 (pt)
JP (1) JP3042915B2 (pt)
KR (1) KR100203236B1 (pt)
AT (1) ATE123493T1 (pt)
AU (1) AU640590B2 (pt)
CA (1) CA2050875C (pt)
CZ (1) CZ280883B6 (pt)
DE (1) DE69110219T2 (pt)
DK (1) DK0475352T3 (pt)
ES (1) ES2074618T3 (pt)
FI (1) FI914219A (pt)
HU (1) HUT59126A (pt)
IE (1) IE67442B1 (pt)
IL (1) IL99434A (pt)
NO (1) NO913543L (pt)
NZ (1) NZ239692A (pt)
PL (1) PL295728A1 (pt)
PT (1) PT98911B (pt)
ZA (1) ZA917141B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL288420A1 (en) * 1989-12-27 1992-06-15 Hoechst Roussel Pharma Method of obtaining derivatives of aminopyridinylomethanoles and aminomethylpyridine amines
US7211594B2 (en) 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
US6897231B2 (en) 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
CN1300116C (zh) * 2001-04-16 2007-02-14 卫材株式会社 1h-吲唑化合物
EP1720855A4 (en) * 2004-03-02 2008-12-17 Smithkline Beecham Corp HEMMER OF ACT ACTIVITY
US7812045B2 (en) * 2005-03-30 2010-10-12 Daewoong Pharmaceutical Co., Ltd. Antifungal triazole derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them

Also Published As

Publication number Publication date
ZA917141B (en) 1992-04-29
CS277691A3 (en) 1992-04-15
IE913157A1 (en) 1992-03-11
IL99434A (en) 1995-08-31
PT98911B (pt) 1999-02-26
US5051430A (en) 1991-09-24
EP0475352A1 (en) 1992-03-18
KR920006346A (ko) 1992-04-27
FI914219A0 (fi) 1991-09-06
HUT59126A (en) 1992-04-28
CZ280883B6 (cs) 1996-04-17
CA2050875C (en) 2002-07-16
JPH04247079A (ja) 1992-09-03
KR100203236B1 (ko) 1999-06-15
ES2074618T3 (es) 1995-09-16
IL99434A0 (en) 1992-08-18
DE69110219T2 (de) 1995-11-09
EP0475352B1 (en) 1995-06-07
NZ239692A (en) 1994-01-26
CA2050875A1 (en) 1992-03-11
AU640590B2 (en) 1993-08-26
AU8371691A (en) 1992-03-12
ATE123493T1 (de) 1995-06-15
IE67442B1 (en) 1996-04-03
PL295728A1 (en) 1993-05-04
FI914219A (fi) 1992-03-11
HU912901D0 (en) 1992-01-28
DE69110219D1 (de) 1995-07-13
JP3042915B2 (ja) 2000-05-22
DK0475352T3 (da) 1995-10-16
NO913543D0 (no) 1991-09-09
NO913543L (no) 1992-03-11

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920330

FG3A Patent granted, date of granting

Effective date: 19981106

MM3A Annulment or lapse

Effective date: 20050506