PT95988A - Processo para a desidratacao de intermediarios corticoesteroides - Google Patents

Processo para a desidratacao de intermediarios corticoesteroides Download PDF

Info

Publication number
PT95988A
PT95988A PT95988A PT9598890A PT95988A PT 95988 A PT95988 A PT 95988A PT 95988 A PT95988 A PT 95988A PT 9598890 A PT9598890 A PT 9598890A PT 95988 A PT95988 A PT 95988A
Authority
PT
Portugal
Prior art keywords
lower alkyl
formula
compound
independently
acid
Prior art date
Application number
PT95988A
Other languages
English (en)
Portuguese (pt)
Inventor
Nicholas Carruthers
Sohaila Garshasb
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PT95988A publication Critical patent/PT95988A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Tires In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PT95988A 1989-11-27 1990-11-23 Processo para a desidratacao de intermediarios corticoesteroides PT95988A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44150089A 1989-11-27 1989-11-27

Publications (1)

Publication Number Publication Date
PT95988A true PT95988A (pt) 1991-09-13

Family

ID=23753123

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95988A PT95988A (pt) 1989-11-27 1990-11-23 Processo para a desidratacao de intermediarios corticoesteroides

Country Status (14)

Country Link
EP (1) EP0502112A1 (oth)
JP (1) JPH05504561A (oth)
KR (1) KR927003619A (oth)
AU (1) AU636433B2 (oth)
CA (1) CA2069645A1 (oth)
HU (1) HUT61030A (oth)
IE (1) IE904252A1 (oth)
IL (1) IL96459A0 (oth)
MY (1) MY105302A (oth)
NZ (1) NZ236206A (oth)
PT (1) PT95988A (oth)
TW (1) TW218022B (oth)
WO (1) WO1991008218A1 (oth)
ZA (1) ZA909444B (oth)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108033990A (zh) * 2017-12-29 2018-05-15 广西万德药业有限公司 地塞米松中间体的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4102907A (en) * 1977-03-07 1978-07-25 The Upjohn Company Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione
US4127596A (en) * 1977-04-11 1978-11-28 The Upjohn Company Non-aromatic oxygenated strong acid dehydration of 9α-hydroxyandrostenediones
FR2493324B1 (oth) * 1980-11-05 1983-01-21 Roussel Uclaf
US4585590A (en) * 1984-02-03 1986-04-29 The Upjohn Company Cyanohydrin process
US5352809A (en) * 1986-10-10 1994-10-04 Gist-Brocades N.V. 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids
PT87687B (pt) * 1987-06-12 1992-09-30 Gist Brocades Nv Processo para a preparacao de esteroides de 9(11)-dehidro
AU618350B2 (en) * 1988-04-08 1991-12-19 Aventis Pharma S.A. 9-alpha-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids

Also Published As

Publication number Publication date
NZ236206A (en) 1993-03-26
AU6962591A (en) 1991-06-26
MY105302A (en) 1994-09-30
WO1991008218A1 (en) 1991-06-13
ZA909444B (en) 1991-08-28
IL96459A0 (en) 1991-08-16
EP0502112A1 (en) 1992-09-09
HU9201750D0 (en) 1992-08-28
KR927003619A (ko) 1992-12-18
AU636433B2 (en) 1993-04-29
IE904252A1 (en) 1991-06-05
HUT61030A (en) 1992-11-30
CA2069645A1 (en) 1991-05-28
JPH05504561A (ja) 1993-07-15
TW218022B (oth) 1993-12-21

Similar Documents

Publication Publication Date Title
AU764572B2 (en) Preparation of sterol and stanol-esters
ES2388371T3 (es) N-{1-[3-(2-etoxi-5-(4-etilpiperazinil)bencenosulfonil)-4,5-dihidro-5-oxo-1,2,4-triazin-6-il]etil}-butiramida, método de preparación y uso
ES2339696T3 (es) Sintesis exo- y diastereo-selectivas de analogos de himbacina.
EP0200377A2 (en) Hydroxamates
Bass et al. Carbon-13 nuclear magnetic resonance spectral properties of alkyl disulfides, thiolsulfinates, and thiolsulfonates
ES2262290T3 (es) Procedimiento de preparacion de esteres de esterol y estanol.
Eggerding et al. Synthesis of the monothiosquarate and 1, 2-dithiosquarate ions and their derivatives
JP6285969B2 (ja) (2s,5r)−7−オキソ−6−スルホオキシ−2−[((3r)−ピペリジン−3−カルボニル)−ヒドラジノカルボニル]−1,6−ジアザ−ビシクロ[3.2.1]オクタンの調製のためのプロセス
PT95037B (pt) Processo para a preparacao de novos 2,3-dihidro-5-oxi-4,6,7-trimetilobenzofuranos 2-(rs)-substituidos, e de composicoes farmaceuticas que os contem
PT95988A (pt) Processo para a desidratacao de intermediarios corticoesteroides
US4865765A (en) Ursodeoxycholic acid derivatives and their inorganic and organic salts having therapeutic activity, and process for preparing the same
PT1529777E (pt) Processo e intermediário oxazolidina para a síntese de taxanos
WO2020119345A1 (zh) 用于制备软海绵素类化合物的中间体及其制备方法
JPH04297461A (ja) 2−チオヒダントイン誘導体
PT2315755E (pt) Síntese de dióis de di-hidrotieno[3,2-d]pirimidina e de dióis de pirimidina semelhantes
Xia et al. The chemical synthesis of a series of ether phospholipids from d-mannitol and their properties
Braverman et al. Synthesis of mono-and disubstituted sulfines via β-elimination of chloroform from trichloromethyl sulfoxides
US2017004A (en) Sulphuric acid derivative of organic sulphur compounds
PT842166E (pt) Processo para sintetizar intermediarios de cadeia lateral de carbapenem
PT100518A (pt) Derivados de 1,4-benzotiazepina-3 (2h)ona,seu uso e processo de preparacao e composicoes farmaceuticas que os contem
Juaristi et al. Conformational analysis of 5-substituted 1, 3-dioxanes. 2. Phenylthio and cyclohexylthio groups and their sulfinyl and sulfonyl derivatives
KR890005301B1 (ko) 티올술피네이트 화합물의 제조방법
ES2287022T3 (es) Esteroides de la serie de los androst-9(11)-enos sustituidos con halogeno en c-19, sustituidos en posicion 5 o condensados con carbociclos en las posiciones 6,10, procedimiento para su preparacion, asi como su utilizacion.
PT90795A (pt) Processo para a preparacao de derivados de n-sulfamil-propionamidina
Hoff et al. Chemistry of acetamidoalkenethiolates III. Synthesis of substituted 1, 4, 2‐oxathiazines and 1, 3, 4‐thiadiazines

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910410

FC3A Refusal

Effective date: 19961129