PT93366A - Processo para a preparacao de novas insulinas glicosiladas especificamente e decomposicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de novas insulinas glicosiladas especificamente e decomposicoes farmaceuticas que as contem Download PDF

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Publication number
PT93366A
PT93366A PT93366A PT9336690A PT93366A PT 93366 A PT93366 A PT 93366A PT 93366 A PT93366 A PT 93366A PT 9336690 A PT9336690 A PT 9336690A PT 93366 A PT93366 A PT 93366A
Authority
PT
Portugal
Prior art keywords
insulin
preparation
human
glycosylated
starting compounds
Prior art date
Application number
PT93366A
Other languages
English (en)
Portuguese (pt)
Inventor
John Broberg Halstrom
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PT93366A publication Critical patent/PT93366A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT93366A 1989-03-08 1990-03-07 Processo para a preparacao de novas insulinas glicosiladas especificamente e decomposicoes farmaceuticas que as contem PT93366A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK111489A DK111489D0 (da) 1989-03-08 1989-03-08 Peptider

Publications (1)

Publication Number Publication Date
PT93366A true PT93366A (pt) 1990-11-07

Family

ID=8101165

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93366A PT93366A (pt) 1989-03-08 1990-03-07 Processo para a preparacao de novas insulinas glicosiladas especificamente e decomposicoes farmaceuticas que as contem

Country Status (19)

Country Link
EP (1) EP0462192A1 (ko)
JP (1) JPH04504117A (ko)
KR (1) KR920701249A (ko)
CN (1) CN1045586A (ko)
AU (1) AU638701B2 (ko)
CA (1) CA2049937A1 (ko)
CS (1) CS114290A3 (ko)
DD (1) DD296933A5 (ko)
DK (1) DK111489D0 (ko)
FI (1) FI914226A0 (ko)
GR (1) GR1000604B (ko)
HU (1) HUT59942A (ko)
IL (1) IL93674A0 (ko)
NO (1) NO913517L (ko)
NZ (1) NZ232808A (ko)
PT (1) PT93366A (ko)
WO (1) WO1990010645A1 (ko)
YU (1) YU45490A (ko)
ZA (1) ZA901737B (ko)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
CA2750223A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
PE20120583A1 (es) 2009-01-28 2012-05-19 Smartcells Inc Sistemas basados en conjugados para entrega farmacologica controlada
KR20140054404A (ko) 2009-01-28 2014-05-08 스마트쎌스, 인크. 결정질 인슐린-접합체
US8623345B2 (en) 2009-03-20 2014-01-07 Smartcells Terminally-functionalized conjugates and uses thereof
US8569231B2 (en) 2009-03-20 2013-10-29 Smartcells, Inc. Soluble non-depot insulin conjugates and uses thereof
WO2012015691A2 (en) 2010-07-28 2012-02-02 Smartcells, Inc. Recombinant lectins, binding-site modified lectins and uses thereof
EP2598527A4 (en) 2010-07-28 2014-01-08 Smartcells Inc RECOMBINANT EXPRESSED INSULIN POLYPEPTIDES AND APPLICATIONS THEREOF
US8933207B2 (en) 2010-07-28 2015-01-13 Smartcells, Inc. Drug-ligand conjugates, synthesis thereof, and intermediates thereto
US9624287B2 (en) 2012-07-17 2017-04-18 Case Western Reserve University O-linked carbohydrate-modified insulin analogues
WO2014015078A1 (en) * 2012-07-17 2014-01-23 Michael Weiss O-linked carbohydrate-modified insulin analogues
ES2670969T3 (es) 2012-11-13 2018-06-04 Adocia Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido
US9707276B2 (en) 2012-12-03 2017-07-18 Merck Sharp & Dohme Corp. O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
CN105358531B (zh) 2013-03-14 2017-11-14 利兰-斯坦福大学初级学院的董事会 线粒体醛脱氢酶‑2调节剂和其使用方法
TW201605470A (zh) 2013-10-04 2016-02-16 默沙東藥廠 葡萄糖反應性胰島素結合物
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN105709207A (zh) * 2016-01-29 2016-06-29 徐宝贞 一种用于治疗痛风的药物
CN105535927A (zh) * 2016-01-29 2016-05-04 山东中海制药有限公司 一种用于治疗流感、上呼吸道感染、病毒性肺炎的药物
CN105597080A (zh) 2016-01-29 2016-05-25 程潜 一种用于治疗尿毒症和尿蛋白的药物
JP2019520342A (ja) 2016-06-02 2019-07-18 サノフイＳａｎｏｆｉ グルコース感知タンパク質に結合することができる薬剤および部分のコンジュゲート

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3847890A (en) * 1971-11-01 1974-11-12 A Green Acidic monosaccharide-substituted proteins
US4444683A (en) * 1982-11-17 1984-04-24 University Of Utah Glycosylated insulin derivatives
EP0119650A3 (en) * 1983-03-21 1987-09-30 THE PROCTER & GAMBLE COMPANY Galactosyl-insulin conjugates useful in treating diabetics
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols

Also Published As

Publication number Publication date
WO1990010645A1 (en) 1990-09-20
CA2049937A1 (en) 1990-09-09
ZA901737B (en) 1990-11-28
NZ232808A (en) 1992-04-28
DD296933A5 (de) 1991-12-19
IL93674A0 (en) 1990-12-23
AU638701B2 (en) 1993-07-08
DK111489D0 (da) 1989-03-08
GR1000604B (el) 1992-08-26
CN1045586A (zh) 1990-09-26
CS114290A3 (en) 1992-02-19
AU5280790A (en) 1990-10-09
YU45490A (en) 1991-10-31
HU902787D0 (en) 1991-11-28
JPH04504117A (ja) 1992-07-23
GR900100159A (en) 1990-07-31
NO913517L (no) 1991-11-06
HUT59942A (en) 1992-07-28
FI914226A0 (fi) 1991-09-06
NO913517D0 (no) 1991-09-06
EP0462192A1 (en) 1991-12-27
KR920701249A (ko) 1992-08-11

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Effective date: 19960102