PT93263A - Processo para a preparacao de 19-nor esteroides contendo na posicao 11-beta umacadeia carbonada possuindo uma funcao amida ou carbamato - Google Patents

Processo para a preparacao de 19-nor esteroides contendo na posicao 11-beta umacadeia carbonada possuindo uma funcao amida ou carbamato

Info

Publication number
PT93263A
PT93263A PT93263A PT9326390A PT93263A PT 93263 A PT93263 A PT 93263A PT 93263 A PT93263 A PT 93263A PT 9326390 A PT9326390 A PT 9326390A PT 93263 A PT93263 A PT 93263A
Authority
PT
Portugal
Prior art keywords
alkyl
optionally
preparation
arylene
image
Prior art date
Application number
PT93263A
Other languages
English (en)
Other versions
PT93263B (pt
Inventor
Lucien Nedelec
Daniel Philibert
Patrick Van De Velde
Andre Claussner
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT93263A publication Critical patent/PT93263A/pt
Publication of PT93263B publication Critical patent/PT93263B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT93263A 1989-02-24 1990-02-23 Processo para a preparacao de 19-nor esteroides contendo na posicao 11-beta umacadeia carbonada possuindo uma funcao amida ou carbamato PT93263B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8902384A FR2643638B1 (fr) 1989-02-24 1989-02-24 Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
PT93263A true PT93263A (pt) 1990-08-31
PT93263B PT93263B (pt) 1996-01-31

Family

ID=9379072

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93263A PT93263B (pt) 1989-02-24 1990-02-23 Processo para a preparacao de 19-nor esteroides contendo na posicao 11-beta umacadeia carbonada possuindo uma funcao amida ou carbamato

Country Status (23)

Country Link
US (2) US5149696A (pt)
EP (1) EP0384842B1 (pt)
JP (1) JP3009169B2 (pt)
KR (1) KR910015590A (pt)
CN (1) CN1046166A (pt)
AT (1) ATE99320T1 (pt)
AU (1) AU631853B2 (pt)
CA (1) CA2010826A1 (pt)
DE (1) DE69005480T2 (pt)
DK (1) DK0384842T3 (pt)
ES (1) ES2062431T3 (pt)
FI (1) FI900925A7 (pt)
FR (1) FR2643638B1 (pt)
HU (1) HU207341B (pt)
IE (1) IE63483B1 (pt)
IL (1) IL93500A0 (pt)
MA (1) MA21754A1 (pt)
MX (1) MX19599A (pt)
OA (1) OA09195A (pt)
PL (1) PL162151B1 (pt)
PT (1) PT93263B (pt)
TN (1) TNSN90018A1 (pt)
ZA (1) ZA901356B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2650748B1 (fr) * 1989-08-08 1991-11-08 Roussel Uclaf Nouveaux esters d'acides organiques avec des alcools derives de 19-nor steroides et leurs sels, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicaments et les compositions les renfermant
EP0471612B1 (fr) * 1990-08-14 1998-01-28 Roussel Uclaf Nouveaux 19-Nor stéroides ayant en position 11béta une chaíne carbonée comportant une fonction amide, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
GB9126766D0 (en) * 1991-12-17 1992-02-12 Coombes Raoul C D Pharmaceutical compositions
FR2685332A1 (fr) * 1991-12-20 1993-06-25 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments.
FR2700548B1 (fr) * 1993-01-20 1995-03-03 Roussel Uclaf Nouveau procédé de préparation de stéroïdes 16 alpha-méthylés.
FR2706454B1 (fr) * 1993-06-17 1995-09-15 Roussel Uclaf Nouveaux 19-Nor stéroïdes, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les contenant.
ATE156836T1 (de) * 1994-05-19 1997-08-15 Akzo Nobel Nv 11,21-bisphenyl-19-nor-pregnan derivate
JP3744559B2 (ja) * 1995-03-17 2006-02-15 独立行政法人情報通信研究機構 立体カメラ、立体ディスプレイ、及び、立体映像システム
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
FR2757519B1 (fr) 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
DE19724187A1 (de) 1997-06-02 1998-12-03 Schering Ag 11beta-Arylsubstituierte 14,17-Ethanoestratriene, Verfahren zur Herstellung dieser Verbindungen, sowie ihre Verwendung zur Herstellung von Arzneimitteln
FR2771096B1 (fr) * 1997-11-17 2000-08-11 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
US6262042B1 (en) 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
FR2789993B1 (fr) * 1999-02-22 2003-03-07 Hoechst Marion Roussel Inc Nouveaux derives de steroides, leurs procedes de preparation et intermediaires de ce procede, leur application a titre de medicaments et compositions pharmaceutiques les renfermant
DE19929715A1 (de) * 1999-06-24 2000-12-28 Schering Ag 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
US20040166189A1 (en) * 2003-02-25 2004-08-26 Mold-Masters Limited Injection molding system with flow control
DE102009034367A1 (de) * 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
WO2012058463A2 (en) 2010-10-27 2012-05-03 Dignity Health Trimegestone (tmg) for treatment of preterm birth

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235949B1 (pt) * 1973-06-18 1978-03-17 Roussel Uclaf
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
GB8327256D0 (en) * 1983-10-12 1983-11-16 Ici Plc Steroid derivatives
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
GB8513723D0 (en) * 1985-05-31 1985-07-03 Erba Farmitalia 11-beta substituted steroids
DE3621024C2 (de) * 1986-06-20 1999-10-28 Schering Ag 11beta-Phenylestradiene, deren Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
JPH02268194A (ja) 1990-11-01
KR910015590A (ko) 1991-09-30
EP0384842A1 (fr) 1990-08-29
AU5007290A (en) 1990-08-30
MX19599A (es) 1994-04-29
PT93263B (pt) 1996-01-31
CA2010826A1 (fr) 1990-08-24
IE63483B1 (en) 1995-05-03
FI900925A7 (fi) 1990-08-25
AU631853B2 (en) 1992-12-10
TNSN90018A1 (fr) 1991-03-05
FR2643638A1 (fr) 1990-08-31
FR2643638B1 (fr) 1991-06-14
MA21754A1 (fr) 1990-10-01
JP3009169B2 (ja) 2000-02-14
DE69005480D1 (de) 1994-02-10
HU900273D0 (en) 1990-03-28
ES2062431T3 (es) 1994-12-16
EP0384842B1 (fr) 1993-12-29
US5290771A (en) 1994-03-01
PL283941A1 (en) 1991-01-14
HU207341B (en) 1993-03-29
IL93500A0 (en) 1990-11-29
CN1046166A (zh) 1990-10-17
ZA901356B (en) 1991-04-24
US5149696A (en) 1992-09-22
DK0384842T3 (da) 1994-03-28
IE900662L (en) 1990-08-24
FI900925A0 (fi) 1990-02-23
OA09195A (fr) 1992-06-30
DE69005480T2 (de) 1994-05-19
ATE99320T1 (de) 1994-01-15
PL162151B1 (en) 1993-09-30
HUT55032A (en) 1991-04-29

Similar Documents

Publication Publication Date Title
ZA901356B (en) 19-nor steroids having in position 11beta a carbonated chain containing an amide or carbamate function,their preparation process and the intermediates of this process,their use as medicaments and the pharmaceutical compositions containing them
ES2071681T3 (es) Compuestos macrociclicos.
DK0972762T3 (da) Hidtil ukendte strukturelle analoger af vitamin D
ATE21699T1 (de) Verfahren zur herstellung von 2-penemverbindungen.
RO75588A (ro) Procedeu pentru prepararea n-fenil-n'-(2-clor-6-fluor-benzoil)-ureelor substituite
DE69402114D1 (de) Neue 19-Nor-Steroide mit einer 11-Beta-Phenoxysulfonamid- oder 11-Beta-Phenoxysulfonylurea-Gruppe, Verfahren und Zwischenprodukte zu ihrer Herstellung sowie Medikamenten und pharmazeutische Präparate davon
DK0624574T3 (da) Hidtil ukendte prostaglandinanaloger
BR8807325A (pt) Polieteruretana,processo para sua preparacao,agentes auxiliares de processamento e aplicacao da polieteruretana
PT98681A (pt) Processo para a preparacao de novos 19-nor esteroides que tem na posicao 11b uma cadeia de atomos de carbono com uma funcao amida e de composicoes farmaceuticas que os contem
ATE107656T1 (de) Verfahren zur herstellung von 14-alpha-hydroxy-4- androsten-3,6,17, trion.
PT93915A (pt) Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem
FR2632521B1 (fr) Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent
FI96856C (fi) Menetelmä terapeuttisesti käyttökelpoisten aminoketonijohdannaisten valmistamiseksi
ATE110716T1 (de) 1-arylsulfonyl-2-piperidinon-derivate, verfahren und zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und sie enthaltende zusammensetzungen.
ATE55123T1 (de) Alkylcarbonsaeureamide von pyridinalkylaminen, ihre herstellung und ihre verwendung als arzneimittel.
EP0351676A3 (de) Benzothiazolone
ES497823A0 (es) Un procedimiento para la preparacion de derivados de tirosi-na.
BR8100315A (pt) Processo para a preparacao de esteres de indan-4-ilo de acidos n-alquil-carbamicos, composicoes fungicidas, processo para o combate de fungos e processo para preparar composicoes fungicidas
JPS56167663A (en) Preparation of novel allyl sulfide

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19951017

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19990430

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011