DK0624574T3 - Hidtil ukendte prostaglandinanaloger - Google Patents

Hidtil ukendte prostaglandinanaloger

Info

Publication number
DK0624574T3
DK0624574T3 DK94111337T DK94111337T DK0624574T3 DK 0624574 T3 DK0624574 T3 DK 0624574T3 DK 94111337 T DK94111337 T DK 94111337T DK 94111337 T DK94111337 T DK 94111337T DK 0624574 T3 DK0624574 T3 DK 0624574T3
Authority
DK
Denmark
Prior art keywords
hitherto unknown
prostaglandin analogues
prostaglandin
analogues
hitherto
Prior art date
Application number
DK94111337T
Other languages
English (en)
Inventor
Toshihide C O Seikagak Inomata
Arata Yasuda
Yutaka Mizushima
Original Assignee
Seikagaku Kogyo Co Ltd
Yoshitomi Pharmaceutical
Asahi Glass Co Ltd
Yutaka Mizushima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd, Yoshitomi Pharmaceutical, Asahi Glass Co Ltd, Yutaka Mizushima filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of DK0624574T3 publication Critical patent/DK0624574T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DK94111337T 1989-10-16 1990-10-15 Hidtil ukendte prostaglandinanaloger DK0624574T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1266230A JP2602964B2 (ja) 1989-10-16 1989-10-16 プロスタグランジン類縁体およびその脂肪乳剤

Publications (1)

Publication Number Publication Date
DK0624574T3 true DK0624574T3 (da) 1999-10-25

Family

ID=17428079

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94111337T DK0624574T3 (da) 1989-10-16 1990-10-15 Hidtil ukendte prostaglandinanaloger
DK90119772.3T DK0423697T3 (da) 1989-10-16 1990-10-15 Lipidemulsion indeholdende en prostaglandinanalog

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90119772.3T DK0423697T3 (da) 1989-10-16 1990-10-15 Lipidemulsion indeholdende en prostaglandinanalog

Country Status (10)

Country Link
US (1) US5120870A (da)
EP (2) EP0624574B1 (da)
JP (1) JP2602964B2 (da)
AT (2) ATE179169T1 (da)
AU (1) AU641436B2 (da)
CA (1) CA2027351C (da)
DE (2) DE69016567T2 (da)
DK (2) DK0624574T3 (da)
ES (2) ES2070238T3 (da)
GR (2) GR3015963T3 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE269302T1 (de) * 1994-01-18 2004-07-15 Teijin Ltd 7-thiaprostaglandine und verfahren zu ihrer herstellung
KR20010023360A (ko) 1997-08-27 2001-03-26 미즈시마 유타카 혈관신생 촉진제
US6632958B1 (en) 1998-06-04 2003-10-14 Mitsubishi Pharma Corporation Process for producing a purified prostaglandin derivative
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
MXPA04002446A (es) 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
EP1711163A2 (en) * 2004-02-05 2006-10-18 Baxter International Inc. Dispersions prepared by use of self-stabilizing agents
KR101319772B1 (ko) * 2004-11-09 2013-10-23 노바갈리 파르마 에스 에이 면역 억제제를 포함하는 안과용 유제
ATE412400T1 (de) 2004-11-09 2008-11-15 Novagali Pharma Sa Öl-in-wasser-emulsion mit niedriger konzentration des kationischen mittels und positivem zetapotential
JP5247453B2 (ja) * 2005-10-10 2013-07-24 ノバガリ ファルマ エスア プロスタグランジン含有眼科用カチオン性水中油型エマルジョン
JP5193870B2 (ja) 2006-09-05 2013-05-08 キユーピー株式会社 プロスタグランジン脂肪乳剤およびその製造方法、ならびにその安定化方法および乳化剤
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
EP2228058A1 (en) 2009-03-04 2010-09-15 Novagali Pharma S.A. Anionic oil-in-water emulsion containing prostaglandins and uses thereof
EP2389939A1 (en) 2010-05-28 2011-11-30 Novagali Pharma S.A. Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
SG187770A1 (en) 2010-08-12 2013-03-28 Univ Nanyang Tech A liposomal formulation for ocular drug delivery
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4363817A (en) * 1981-08-27 1982-12-14 Miles Laboratories, Inc. Enol acylate analogs of E1 and E2 prostaglandins
JPS58222014A (ja) * 1982-06-18 1983-12-23 Taisho Pharmaceut Co Ltd プロスタグランジンｅ↓１脂肪乳剤
JPS59216820A (ja) * 1983-05-20 1984-12-06 Taisho Pharmaceut Co Ltd プロスタグランジン脂肪乳剤
JPH0818989B2 (ja) * 1984-01-12 1996-02-28 株式会社ミドリ十字 脂肪乳剤中のプロスタグランジンの安定化方法
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
JPS61151126A (ja) * 1984-12-25 1986-07-09 Teijin Ltd △７―プロスタグランジンａ１類を有効成分として含有する注射用の脂肪乳剤

Also Published As

Publication number Publication date
ATE117989T1 (de) 1995-02-15
EP0624574B1 (en) 1999-04-21
EP0423697A3 (en) 1992-08-05
JPH03204853A (ja) 1991-09-06
DK0423697T3 (da) 1995-05-29
EP0423697B1 (en) 1995-02-01
DE69033069T2 (de) 1999-08-19
US5120870A (en) 1992-06-09
EP0624574A2 (en) 1994-11-17
GR3030718T3 (en) 1999-11-30
ATE179169T1 (de) 1999-05-15
DE69016567T2 (de) 1995-09-21
ES2070238T3 (es) 1995-06-01
GR3015963T3 (en) 1995-07-31
DE69016567D1 (de) 1995-03-16
ES2132279T3 (es) 1999-08-16
AU641436B2 (en) 1993-09-23
EP0423697A2 (en) 1991-04-24
JP2602964B2 (ja) 1997-04-23
DE69033069D1 (de) 1999-05-27
CA2027351A1 (en) 1991-04-17
CA2027351C (en) 2001-06-19
EP0624574A3 (en) 1995-01-18
AU6452690A (en) 1991-04-18

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