PT93915A - Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem

Info

Publication number
PT93915A
PT93915A PT93915A PT9391590A PT93915A PT 93915 A PT93915 A PT 93915A PT 93915 A PT93915 A PT 93915A PT 9391590 A PT9391590 A PT 9391590A PT 93915 A PT93915 A PT 93915A
Authority
PT
Portugal
Prior art keywords
indol
phenyl
methyl
preparation
pharmaceutical compositions
Prior art date
Application number
PT93915A
Other languages
English (en)
Other versions
PT93915B (pt
Inventor
Francois Clemence
Jacques Guillaume
Gilles Hamon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT93915A publication Critical patent/PT93915A/pt
Publication of PT93915B publication Critical patent/PT93915B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT93915A 1989-04-28 1990-04-27 Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem PT93915B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8905650A FR2646349B1 (fr) 1989-04-28 1989-04-28 Derives du 4-phenylmethyl lh-indole, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Publications (2)

Publication Number Publication Date
PT93915A true PT93915A (pt) 1990-11-20
PT93915B PT93915B (pt) 1996-10-31

Family

ID=9381227

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93915A PT93915B (pt) 1989-04-28 1990-04-27 Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US5086070A (pt)
EP (1) EP0395528B1 (pt)
JP (1) JPH0368554A (pt)
AT (1) ATE124685T1 (pt)
AU (1) AU628968B2 (pt)
CA (1) CA2015669A1 (pt)
DE (1) DE69020632T2 (pt)
DK (1) DK0395528T3 (pt)
ES (1) ES2074144T3 (pt)
FR (1) FR2646349B1 (pt)
HU (1) HUT54642A (pt)
MX (1) MX20482A (pt)
NZ (1) NZ233478A (pt)
PT (1) PT93915B (pt)
RU (1) RU2067576C1 (pt)
ZA (1) ZA903139B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908367A (en) * 1985-07-11 1990-03-13 Roussel Uclaf N-(1H-indole-4-yl)-benzamides
CH687764A5 (de) * 1992-07-02 1997-02-14 Lonza Ag Gampel Wallis Geschof Verfahren zur Herstellung von 7-Acylindolen.
CN1094487C (zh) 1994-04-01 2002-11-20 盐野义制药株式会社 肟衍生物和含有其作为活性成分的杀菌剂
US6268312B1 (en) 1994-04-01 2001-07-31 Shionogi & Co., Ltd. Oxime derivative and bactericide containing the same as active ingredient
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
BRPI0916774A2 (pt) * 2008-07-15 2018-02-20 Hoffmann La Roche derivados de indolila e indazolila substituídos e usos dos mesmos
CN109475530B (zh) * 2016-05-23 2022-03-01 洛克菲勒大学 用于治疗自身免疫性疾病的氨酰基吲唑免疫调节剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584070B1 (fr) * 1985-06-27 1987-08-28 Roussel Uclaf Nouveaux derives de l'hydroxy alkoxy 4-phenyl propyl indole, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant.
FR2584713B1 (fr) * 1985-07-11 1988-09-09 Roussel Uclaf Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Also Published As

Publication number Publication date
ATE124685T1 (de) 1995-07-15
NZ233478A (en) 1992-08-26
DE69020632T2 (de) 1996-01-11
EP0395528A3 (fr) 1991-11-21
DE69020632D1 (de) 1995-08-10
FR2646349A1 (fr) 1990-11-02
JPH0368554A (ja) 1991-03-25
US5086070A (en) 1992-02-04
AU628968B2 (en) 1992-09-24
PT93915B (pt) 1996-10-31
EP0395528A2 (fr) 1990-10-31
DK0395528T3 (da) 1995-10-30
AU5393190A (en) 1990-11-01
ZA903139B (en) 1991-06-26
EP0395528B1 (fr) 1995-07-05
CA2015669A1 (fr) 1990-10-28
HU902612D0 (en) 1990-09-28
RU2067576C1 (ru) 1996-10-10
ES2074144T3 (es) 1995-09-01
MX20482A (es) 1993-11-01
HUT54642A (en) 1991-03-28
FR2646349B1 (fr) 1994-04-01

Similar Documents

Publication Publication Date Title
PT97254A (pt) Processo para a preparacao de azoles substituido e de composicoes farmaceuticas que os contem
PT91766A (pt) Processo para a preparacao de derivados do acido 3,5-dihidroxihept-6-ina-carboxilico substituidos na posicao, de seus compostos intermedios e de composicoes farmaceuticas que os contem
PT89814A (pt) Processo para a preparacao de novos derivados do estilbeno e de composicoes farmaceuticas que os contem
PT99569A (pt) Processo para a preparacao de novos derivados de eritromicina e de composicoes farmaceuticas que os contem
PT99402A (pt) Processo para a preparacao de derivados de imino ciclicos e de composicoes farmaceuticas que os contem
PT99445A (pt) Processo para preparacao de derivados do 1,4,7,10-tetraazaciclododecano mono-n--substituidos e de composicoes farmaceuticas que os contem
PT95281A (pt) Processo para a preparacao de derivados de 4-benzoil-isoxazol e de composicoes herbicidas que os contem
PT81586B (pt) Processo para a preparacao de derivados de benzoxazol e benzotiazolamina e de composicoes farmaceuticas que os contem
ES2086341T3 (es) Derivados de aminoacidos con propiedades inhibidoras de la renina, procedimiento para su preparacion, agentes que los contienen y su utilizacion.
PT92146A (pt) Processo para a preparacao do inibidor de glicosidade salbostatina e de composicoes farmaceuticas que a contem
BR8802021A (pt) Agentes repelentes de insetos e de acaros,processos para o combate a insetos e acaros e para a preparacao de agentes derivados e processo para sua preparacao
PT101725A (pt) Processo para a preparacao de um composto de diarilo anti-aterosclerotico e de composicoes farmaceuticas que o contem
DK0384842T3 (da) 19-nor-steroider substitueret i 11beta-stillingen med en carbonkæde med en amid- eller carbamatgruppe, deres fremstillingsmetode og mellemprodukter med denne fremstillingsmetode, deres anvendelse som lægemidler og farmaceutiske præparater med indhold deraf
PT83725B (pt) Processo para preparacao de novos derivados da 3-oxadiol-beta-carbolina e 3-carboxilato-beta-carbolina e de composicoes farmaceuticas que os contem
PT93915A (pt) Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem
PT90740A (pt) Processo para a preparacao de oligopeptideos com aminoacidos analogos de prolina ciclicos, e de composicoes farmaceuticas que os contem
ES2070238T3 (es) Emulsion de lipidos que contiene un analogo de prostaglandina.
PT91364A (pt) Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem
PT92558A (pt) Processo para a preparacao de derivados de aminoacidos inibidores de enzimas e de composicoes farmaceuticas que os contem
PT97286A (pt) Processo para a preparacao de novos derivados do 3-aminocromano e de composicoes farmaceuticas que os contem
PT88301A (pt) Processo para a preparacao de derivados de oxima de 1,2,5,6-tetraidropiridina e de composicoes farmaceuticas que os contem
PH20421A (en) Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them
PT91362A (pt) Processo para a preparacao de novos acidos 6-fluor-3,5-di-hidroxi-carboxilicos e seus derivados, e de composicoes farmaceuticas que os contem e de produtos intermediarios
PT89757A (pt) Processo para a preparacao de novos derivados da xantina e de composicoes farmaceuticas que os contem, uteis no tratamento da ulcera peptica
MX9203585A (es) Derivados de fenotiazina y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19960717

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980131