PT93915A - Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem

Info

Publication number
PT93915A
PT93915A PT93915A PT9391590A PT93915A PT 93915 A PT93915 A PT 93915A PT 93915 A PT93915 A PT 93915A PT 9391590 A PT9391590 A PT 9391590A PT 93915 A PT93915 A PT 93915A
Authority
PT
Portugal
Prior art keywords
indol
phenyl
methyl
preparation
pharmaceutical compositions
Prior art date
Application number
PT93915A
Other languages
English (en)
Other versions
PT93915B (pt
Inventor
Francois Clemence
Jacques Guillaume
Gilles Hamon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT93915A publication Critical patent/PT93915A/pt
Publication of PT93915B publication Critical patent/PT93915B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
PT93915A 1989-04-28 1990-04-27 Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem PT93915B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8905650A FR2646349B1 (fr) 1989-04-28 1989-04-28 Derives du 4-phenylmethyl lh-indole, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Publications (2)

Publication Number Publication Date
PT93915A true PT93915A (pt) 1990-11-20
PT93915B PT93915B (pt) 1996-10-31

Family

ID=9381227

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93915A PT93915B (pt) 1989-04-28 1990-04-27 Processo para a preparacao de novos derivados de 4-fenil-metil-1h-indol e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US5086070A (pt)
EP (1) EP0395528B1 (pt)
JP (1) JPH0368554A (pt)
AT (1) ATE124685T1 (pt)
AU (1) AU628968B2 (pt)
CA (1) CA2015669A1 (pt)
DE (1) DE69020632T2 (pt)
DK (1) DK0395528T3 (pt)
ES (1) ES2074144T3 (pt)
FR (1) FR2646349B1 (pt)
HU (1) HUT54642A (pt)
MX (1) MX20482A (pt)
NZ (1) NZ233478A (pt)
PT (1) PT93915B (pt)
RU (1) RU2067576C1 (pt)
ZA (1) ZA903139B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908367A (en) * 1985-07-11 1990-03-13 Roussel Uclaf N-(1H-indole-4-yl)-benzamides
CH687764A5 (de) * 1992-07-02 1997-02-14 Lonza Ag Gampel Wallis Geschof Verfahren zur Herstellung von 7-Acylindolen.
WO1995026956A1 (fr) 1994-04-01 1995-10-12 Shionogi & Co., Ltd. Derive d'oxime et bactericide le contenant en tant qu'ingredient actif
US6268312B1 (en) 1994-04-01 2001-07-31 Shionogi & Co., Ltd. Oxime derivative and bactericide containing the same as active ingredient
US6391907B1 (en) 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6355648B1 (en) 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
BRPI0916774A2 (pt) * 2008-07-15 2018-02-20 Hoffmann La Roche derivados de indolila e indazolila substituídos e usos dos mesmos
WO2017205296A1 (en) * 2016-05-23 2017-11-30 The Rockefeller University Aminoacylindazole immunomodulators for treatment of autoimmune diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584070B1 (fr) * 1985-06-27 1987-08-28 Roussel Uclaf Nouveaux derives de l'hydroxy alkoxy 4-phenyl propyl indole, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant.
FR2584713B1 (fr) * 1985-07-11 1988-09-09 Roussel Uclaf Nouveaux derives de l'indole carboxamide, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant

Also Published As

Publication number Publication date
EP0395528B1 (fr) 1995-07-05
EP0395528A2 (fr) 1990-10-31
ZA903139B (en) 1991-06-26
RU2067576C1 (ru) 1996-10-10
HUT54642A (en) 1991-03-28
DE69020632T2 (de) 1996-01-11
EP0395528A3 (fr) 1991-11-21
FR2646349B1 (fr) 1994-04-01
ES2074144T3 (es) 1995-09-01
PT93915B (pt) 1996-10-31
FR2646349A1 (fr) 1990-11-02
NZ233478A (en) 1992-08-26
DE69020632D1 (de) 1995-08-10
AU628968B2 (en) 1992-09-24
US5086070A (en) 1992-02-04
JPH0368554A (ja) 1991-03-25
HU902612D0 (en) 1990-09-28
AU5393190A (en) 1990-11-01
DK0395528T3 (da) 1995-10-30
MX20482A (es) 1993-11-01
CA2015669A1 (fr) 1990-10-28
ATE124685T1 (de) 1995-07-15

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19960717

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19980131