PT93213A - Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem

Info

Publication number
PT93213A
PT93213A PT93213A PT9321390A PT93213A PT 93213 A PT93213 A PT 93213A PT 93213 A PT93213 A PT 93213A PT 9321390 A PT9321390 A PT 9321390A PT 93213 A PT93213 A PT 93213A
Authority
PT
Portugal
Prior art keywords
hydrogen
pct
ulcerose
allergic
contain
Prior art date
Application number
PT93213A
Other languages
English (en)
Other versions
PT93213B (pt
Inventor
Francesco Makovec
Luigi Rovati
Walter Peris
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of PT93213A publication Critical patent/PT93213A/pt
Publication of PT93213B publication Critical patent/PT93213B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/57Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT93213A 1989-02-22 1990-02-21 Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem PT93213B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8967119A IT1232252B (it) 1989-02-22 1989-02-22 Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
PT93213A true PT93213A (pt) 1990-08-31
PT93213B PT93213B (pt) 1996-01-31

Family

ID=11299739

Family Applications (1)

Application Number Title Priority Date Filing Date
PT93213A PT93213B (pt) 1989-02-22 1990-02-21 Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem

Country Status (16)

Country Link
US (1) US5232937A (pt)
EP (1) EP0460083B1 (pt)
JP (1) JP2716259B2 (pt)
AT (1) ATE106863T1 (pt)
AU (1) AU627285B2 (pt)
CA (1) CA2046874C (pt)
DD (1) DD294477A5 (pt)
DE (1) DE69009746T2 (pt)
ES (1) ES2055424T3 (pt)
GR (1) GR1002183B (pt)
HU (1) HU207986B (pt)
IE (1) IE64437B1 (pt)
IT (1) IT1232252B (pt)
PT (1) PT93213B (pt)
WO (1) WO1990009989A1 (pt)
ZA (1) ZA901316B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
JPH0597706A (ja) * 1991-04-09 1993-04-20 Chemex Block Drug Jv アフタ性潰瘍および他の粘膜皮膚障害の処置方法
IT1256870B (it) * 1992-02-13 1995-12-27 Rotta Research Lab Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva
ES2199336T3 (es) * 1997-08-08 2004-02-16 Rotta Research Laboratorium S.P.A. Una composicion farmaceutica novedosa para inhalacion que contiene cr 2039 (andolast).
US6369091B1 (en) 1998-05-22 2002-04-09 Avanir Pharmaceuticals Benzimidazole analogs as down-regulators of IgE
US6919366B2 (en) 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6303645B1 (en) 1998-05-22 2001-10-16 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
CA2332989A1 (en) * 1998-05-22 1999-12-02 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of ige
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
WO2002072090A1 (en) 2001-03-12 2002-09-19 Avanir Pharmaceuticals Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
TWI319387B (en) * 2002-04-05 2010-01-11 Astrazeneca Ab Benzamide derivatives
US7078423B2 (en) 2002-07-18 2006-07-18 Inotek Pharmaceuticals Corporation 5-Aryltetrazole compounds, compositions thereof, and uses therefor
US7087631B2 (en) * 2002-07-18 2006-08-08 Inotek Pharmaceuticals Corporation Aryltetrazole compounds, and compositions thereof
WO2004024655A2 (en) 2002-09-12 2004-03-25 Avanir Pharmaceuticals Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
US7037927B2 (en) 2003-10-16 2006-05-02 Abbott Laboratories Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
SI1634595T1 (sl) 2004-08-19 2008-12-31 Rottapharm Spa N-fenilbenzamidni derivati kot zdravila za zdravljenje kronične obstruktivne pljučne bolezni (KOPB)
GB0521244D0 (en) * 2005-10-19 2005-11-30 Astrazeneca Ab Benzamide compounds
ES2327265T3 (es) 2006-04-10 2009-10-27 Rottapharm S.P.A. Una nueva forma cristalina estable de andolast.
JP5220741B2 (ja) 2006-07-31 2013-06-26 ロッタファルム・ソシエタ・ペル・アチオニ アンドラスト/グルココルチコイドの併用
US8380355B2 (en) * 2007-03-19 2013-02-19 Wayne/Scott Fetzer Company Capacitive sensor and method and apparatus for controlling a pump using same
BR112014016804A8 (pt) 2012-01-06 2017-07-04 Univ California composições, métodos de uso e métodos de tratamento

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170105B1 (en) * 1984-07-07 1990-10-17 Koichi Prof. Dr. Shudo Benzoic acid derivatives
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
DE3616721A1 (de) * 1986-05-17 1987-11-19 Basf Lacke & Farben Zink- und/oder bleisalze von carbonsaeuren und deren verwendung als korrosionsschutzmittel
US4835181A (en) * 1987-02-18 1989-05-30 Eli Lilly And Company Anticonvulsant agents using cyano dimethylphenyl benzamides
IL85896A (en) * 1987-04-06 1993-01-14 Riker Laboratories Inc Substituted di-tert.- butylphenols and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ATE106863T1 (de) 1994-06-15
AU627285B2 (en) 1992-08-20
ES2055424T3 (es) 1994-08-16
CA2046874C (en) 1999-03-23
HUT60464A (en) 1992-09-28
EP0460083A1 (en) 1991-12-11
PT93213B (pt) 1996-01-31
CA2046874A1 (en) 1990-08-23
IT8967119A0 (it) 1989-02-22
WO1990009989A1 (en) 1990-09-07
AU5175690A (en) 1990-09-26
GR900100136A (el) 1991-06-28
DE69009746D1 (de) 1994-07-14
US5232937A (en) 1993-08-03
IE900645L (en) 1990-08-22
JP2716259B2 (ja) 1998-02-18
IT1232252B (it) 1992-01-28
HU207986B (en) 1993-07-28
EP0460083B1 (en) 1994-06-08
ZA901316B (en) 1990-11-28
DE69009746T2 (de) 1994-11-17
GR1002183B (en) 1996-03-12
IE64437B1 (en) 1995-08-09
DD294477A5 (de) 1991-10-02

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19951017

PD3A Change of proprietorship

Free format text: ROTTAPHARM S.P.A. IT

Effective date: 20050329

TE3A Change of address (patent)

Free format text: ROTTAPHARM S.P.A. IT

Effective date: 20050412