IT8967119A0 - Derivati della n fenil benzamide adattivita antiulcera ed antiallergi ca e procedimento per la loro preparazione - Google Patents

Derivati della n fenil benzamide adattivita antiulcera ed antiallergi ca e procedimento per la loro preparazione

Info

Publication number
IT8967119A0
IT8967119A0 IT8967119A IT6711989A IT8967119A0 IT 8967119 A0 IT8967119 A0 IT 8967119A0 IT 8967119 A IT8967119 A IT 8967119A IT 6711989 A IT6711989 A IT 6711989A IT 8967119 A0 IT8967119 A0 IT 8967119A0
Authority
IT
Italy
Prior art keywords
antiulcera
adaptivity
antiallergic
derivatives
procedure
Prior art date
Application number
IT8967119A
Other languages
English (en)
Other versions
IT1232252B (it
Inventor
Makovec Francesco Peris Walter
Rovati Luigi
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of IT8967119A0 publication Critical patent/IT8967119A0/it
Priority to IT8967119A priority Critical patent/IT1232252B/it
Priority to US07/752,435 priority patent/US5232937A/en
Priority to CA002046874A priority patent/CA2046874C/en
Priority to AU51756/90A priority patent/AU627285B2/en
Priority to EP90904335A priority patent/EP0460083B1/en
Priority to JP2504144A priority patent/JP2716259B2/ja
Priority to DE69009746T priority patent/DE69009746T2/de
Priority to ES90904335T priority patent/ES2055424T3/es
Priority to AT90904335T priority patent/ATE106863T1/de
Priority to PCT/EP1990/000270 priority patent/WO1990009989A1/en
Priority to HU902321A priority patent/HU207986B/hu
Priority to PT93213A priority patent/PT93213B/pt
Priority to ZA901316A priority patent/ZA901316B/xx
Priority to DD90338029A priority patent/DD294477A5/de
Priority to IE64590A priority patent/IE64437B1/en
Priority to GR900100136A priority patent/GR1002183B/el
Application granted granted Critical
Publication of IT1232252B publication Critical patent/IT1232252B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/56Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/57Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT8967119A 1989-02-22 1989-02-22 Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione IT1232252B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT8967119A IT1232252B (it) 1989-02-22 1989-02-22 Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
AT90904335T ATE106863T1 (de) 1989-02-22 1990-02-19 Derivate von n-phenylbenzamid mit antiulcerativer sowie antiallergischer aktivität und verfahren zu ihrer herstellung.
HU902321A HU207986B (en) 1989-02-22 1990-02-19 Process for producing n-phenyl-benzamide derivatives and pharmaceutical compositions containing them as active components
AU51756/90A AU627285B2 (en) 1989-02-22 1990-02-19 Derivatives of n-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation
EP90904335A EP0460083B1 (en) 1989-02-22 1990-02-19 Derivatives of n-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation
JP2504144A JP2716259B2 (ja) 1989-02-22 1990-02-19 抗潰瘍および抗アレルギー活性を有するn―フェニルベンズアミド誘導体およびその製造法
DE69009746T DE69009746T2 (de) 1989-02-22 1990-02-19 Derivate von n-phenylbenzamid mit antiulcerativer sowie antiallergischer aktivität und verfahren zu ihrer herstellung.
ES90904335T ES2055424T3 (es) 1989-02-22 1990-02-19 Derivados de n-fenilbenzamida con actividad anti-ulcera y anti-alergia y un metodo para su preparacion.
US07/752,435 US5232937A (en) 1989-02-22 1990-02-19 Derivatives of n-phenylbenzamide with anti-ulcer and anti-allergy
PCT/EP1990/000270 WO1990009989A1 (en) 1989-02-22 1990-02-19 Derivatives of n-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation
CA002046874A CA2046874C (en) 1989-02-22 1990-02-19 Derivatives of n-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation
PT93213A PT93213B (pt) 1989-02-22 1990-02-21 Processo para a preparacao de derivados de n-fenilbenzamida com accao anti-ulcerosa e anti-alergica e de composicoes farmaceuticas que os contem
ZA901316A ZA901316B (en) 1989-02-22 1990-02-21 Derivatives of n-phenylbenzamide with anti-ulcer and antiallergy activity and a method for their preparation
DD90338029A DD294477A5 (de) 1989-02-22 1990-02-21 Derivate von n-phenylbenzamid mit wirksamkeit gegen magengeschwuere und allergien sowie verfahren zu ihrer herstellung
IE64590A IE64437B1 (en) 1989-02-22 1990-02-22 Derivatives of N-phenylbenzamide with anti-ulcer and anti-allergy activity and a method for their preparation
GR900100136A GR1002183B (en) 1989-02-22 1990-02-22 Derivatives of n-phenylbenzamide and a method for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8967119A IT1232252B (it) 1989-02-22 1989-02-22 Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
IT8967119A0 true IT8967119A0 (it) 1989-02-22
IT1232252B IT1232252B (it) 1992-01-28

Family

ID=11299739

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8967119A IT1232252B (it) 1989-02-22 1989-02-22 Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione

Country Status (16)

Country Link
US (1) US5232937A (it)
EP (1) EP0460083B1 (it)
JP (1) JP2716259B2 (it)
AT (1) ATE106863T1 (it)
AU (1) AU627285B2 (it)
CA (1) CA2046874C (it)
DD (1) DD294477A5 (it)
DE (1) DE69009746T2 (it)
ES (1) ES2055424T3 (it)
GR (1) GR1002183B (it)
HU (1) HU207986B (it)
IE (1) IE64437B1 (it)
IT (1) IT1232252B (it)
PT (1) PT93213B (it)
WO (1) WO1990009989A1 (it)
ZA (1) ZA901316B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
JPH0597706A (ja) * 1991-04-09 1993-04-20 Chemex Block Drug Jv アフタ性潰瘍および他の粘膜皮膚障害の処置方法
IT1256870B (it) * 1992-02-13 1995-12-27 Rotta Research Lab Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva
ES2199336T3 (es) * 1997-08-08 2004-02-16 Rotta Research Laboratorium S.P.A. Una composicion farmaceutica novedosa para inhalacion que contiene cr 2039 (andolast).
US6369091B1 (en) 1998-05-22 2002-04-09 Avanir Pharmaceuticals Benzimidazole analogs as down-regulators of IgE
NZ508413A (en) 1998-05-22 2003-08-29 Avanir Pharmaceuticals Benzimidazole analogs as down-regulators of IgE
US6303645B1 (en) 1998-05-22 2001-10-16 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6919366B2 (en) 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6911462B2 (en) 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
US6759425B2 (en) 1999-10-21 2004-07-06 Avanir Pharmaceuticals Benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
DE60221804T2 (de) 2001-03-12 2008-05-15 Avanir Pharmaceuticals, San Diego Benzimidazolderivate zur ige-modulierung und zellproliferationshemmung
TWI319387B (en) * 2002-04-05 2010-01-11 Astrazeneca Ab Benzamide derivatives
US7087631B2 (en) 2002-07-18 2006-08-08 Inotek Pharmaceuticals Corporation Aryltetrazole compounds, and compositions thereof
US7078423B2 (en) * 2002-07-18 2006-07-18 Inotek Pharmaceuticals Corporation 5-Aryltetrazole compounds, compositions thereof, and uses therefor
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
US7037927B2 (en) * 2003-10-16 2006-05-02 Abbott Laboratories Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
PL1634595T3 (pl) 2004-08-19 2009-01-30 Rottapharm Spa Pochodne N-fenylobenzamidu jako leki do leczenia COPD
GB0521244D0 (en) * 2005-10-19 2005-11-30 Astrazeneca Ab Benzamide compounds
PL1845093T3 (pl) * 2006-04-10 2009-11-30 Rottapharm Biotech Srl Nowa krystaliczna i stabilna postać andolastu
US8809306B2 (en) 2006-07-31 2014-08-19 Rottapharm S.P.A. Combination andolast/glucocorticoids
US8380355B2 (en) * 2007-03-19 2013-02-19 Wayne/Scott Fetzer Company Capacitive sensor and method and apparatus for controlling a pump using same
AU2013207510A1 (en) * 2012-01-06 2014-07-31 The Regents Of The University Of California Compositions, methods of use, and methods of treatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0170105B1 (en) * 1984-07-07 1990-10-17 Koichi Prof. Dr. Shudo Benzoic acid derivatives
LU86258A1 (fr) * 1986-01-21 1987-09-03 Rech Dermatologiques C I R D S Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique
DE3616721A1 (de) * 1986-05-17 1987-11-19 Basf Lacke & Farben Zink- und/oder bleisalze von carbonsaeuren und deren verwendung als korrosionsschutzmittel
US4835181A (en) * 1987-02-18 1989-05-30 Eli Lilly And Company Anticonvulsant agents using cyano dimethylphenyl benzamides
ZA882251B (en) * 1987-04-06 1989-11-29 Riker Laboratories Inc Substituted di-t-butylphenols

Also Published As

Publication number Publication date
ES2055424T3 (es) 1994-08-16
DE69009746T2 (de) 1994-11-17
HU207986B (en) 1993-07-28
GR900100136A (el) 1991-06-28
PT93213A (pt) 1990-08-31
GR1002183B (en) 1996-03-12
IE64437B1 (en) 1995-08-09
CA2046874C (en) 1999-03-23
IE900645L (en) 1990-08-22
HUT60464A (en) 1992-09-28
IT1232252B (it) 1992-01-28
AU627285B2 (en) 1992-08-20
EP0460083B1 (en) 1994-06-08
DD294477A5 (de) 1991-10-02
CA2046874A1 (en) 1990-08-23
EP0460083A1 (en) 1991-12-11
JP2716259B2 (ja) 1998-02-18
WO1990009989A1 (en) 1990-09-07
PT93213B (pt) 1996-01-31
US5232937A (en) 1993-08-03
AU5175690A (en) 1990-09-26
DE69009746D1 (de) 1994-07-14
ZA901316B (en) 1990-11-28
ATE106863T1 (de) 1994-06-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940228