PT85477A - Process for preparing a phenyl butenamide substituted heterocyclic derivatives - Google Patents

Process for preparing a phenyl butenamide substituted heterocyclic derivatives

Info

Publication number
PT85477A
PT85477A PT85477A PT8547787A PT85477A PT 85477 A PT85477 A PT 85477A PT 85477 A PT85477 A PT 85477A PT 8547787 A PT8547787 A PT 8547787A PT 85477 A PT85477 A PT 85477A
Authority
PT
Portugal
Prior art keywords
alkyl
halo
substituted
phenyl
hydrogen
Prior art date
Application number
PT85477A
Other languages
English (en)
Other versions
PT85477B (pt
Inventor
Peter Thadeus Gallagher
Terence Alan Hicks
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of PT85477A publication Critical patent/PT85477A/pt
Publication of PT85477B publication Critical patent/PT85477B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
PT85477A 1986-08-08 1987-08-04 Processo para a preparacao de derivados heterociclicos substituidos de fenil butenamida PT85477B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868619433A GB8619433D0 (en) 1986-08-08 1986-08-08 Pharmaceutical compounds

Publications (2)

Publication Number Publication Date
PT85477A true PT85477A (en) 1987-09-01
PT85477B PT85477B (pt) 1990-06-29

Family

ID=10602474

Family Applications (1)

Application Number Title Priority Date Filing Date
PT85477A PT85477B (pt) 1986-08-08 1987-08-04 Processo para a preparacao de derivados heterociclicos substituidos de fenil butenamida

Country Status (20)

Country Link
US (1) US4983619A (pt)
EP (1) EP0259972B1 (pt)
JP (1) JPS63246364A (pt)
CN (1) CN1021050C (pt)
AT (1) ATE91489T1 (pt)
AU (1) AU605498B2 (pt)
CA (1) CA1290335C (pt)
DE (1) DE3786507T2 (pt)
DK (1) DK414087A (pt)
EG (1) EG18231A (pt)
ES (1) ES2058118T3 (pt)
GB (1) GB8619433D0 (pt)
HU (1) HU204520B (pt)
IL (1) IL83433A (pt)
MX (1) MX173324B (pt)
NZ (1) NZ221353A (pt)
PH (1) PH23488A (pt)
PT (1) PT85477B (pt)
SU (1) SU1593568A3 (pt)
ZA (1) ZA875812B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001124A (en) * 1990-02-02 1991-03-19 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
US5108999A (en) * 1990-02-02 1992-04-28 Syntex (U.S.A.) Inc. 4-isoxazolecarboxamide derivatives
US5494911A (en) * 1990-05-18 1996-02-27 Hoechst Aktiengesellschaft Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides, pharmaceuticals containing these compounds and their use
JPH06135948A (ja) * 1992-10-30 1994-05-17 Taiho Yakuhin Kogyo Kk スチレン誘導体又はその塩
EP0750496A1 (en) * 1994-03-14 1997-01-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents
AU2014352920A1 (en) 2013-11-22 2016-06-23 Genzyme Corporation Novel methods for treating neurodegenerative diseases
WO2021050556A1 (en) * 2019-09-09 2021-03-18 Rutgers, The State University Of New Jersey Compositions and methods for inhibiting ribosome inactivating proteins

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DK545976A (da) * 1975-12-11 1977-06-12 Hoechst Ag Cyaneddikesyreanilidderivater fremgangsmade til deres fremstilling og midler der indeholder disse forbindelser
DE2655009A1 (de) * 1976-12-04 1978-06-15 Hoechst Ag Isoxazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel
GB1598900A (en) * 1978-05-23 1981-09-23 Lilly Industries Ltd Heterocyclic amino derivatives
CA1133917A (en) * 1979-06-11 1982-10-19 Gordon N. Walker Alphacarbamoyl-pyrrolpropionitriles, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application
DE3331874A1 (de) * 1982-09-13 1984-04-05 Sandoz-Patent-GmbH, 7850 Lörrach Neue thiophenderivate
DE3609542A1 (de) * 1986-03-21 1987-10-01 Bayer Ag 5-acylamino-pyrazol-derivate

Also Published As

Publication number Publication date
GB8619433D0 (en) 1986-09-17
NZ221353A (en) 1990-04-26
DE3786507D1 (de) 1993-08-19
DE3786507T2 (de) 1993-11-11
EP0259972B1 (en) 1993-07-14
AU7668087A (en) 1988-02-11
US4983619A (en) 1991-01-08
DK414087D0 (da) 1987-08-07
SU1593568A3 (ru) 1990-09-15
CN1021050C (zh) 1993-06-02
DK414087A (da) 1988-02-09
EG18231A (en) 1992-10-30
ZA875812B (en) 1989-04-26
MX7667A (es) 1993-09-01
CA1290335C (en) 1991-10-08
EP0259972A2 (en) 1988-03-16
IL83433A0 (en) 1988-01-31
PT85477B (pt) 1990-06-29
HUT46684A (en) 1988-11-28
HU204520B (en) 1992-01-28
PH23488A (en) 1989-08-16
ES2058118T3 (es) 1994-11-01
ATE91489T1 (de) 1993-07-15
MX173324B (es) 1994-02-16
EP0259972A3 (en) 1990-05-02
IL83433A (en) 1992-03-29
AU605498B2 (en) 1991-01-17
CN87105515A (zh) 1988-03-23
JPS63246364A (ja) 1988-10-13

Similar Documents

Publication Publication Date Title
FI893467A (fi) Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
PH25859A (en) Composition for treatment of ischemic disorder
IL103944A0 (en) Piperazine derivatives,their preparation and pharmaceutical compositions containing them
SU1568886A3 (ru) Cпocoб пoлучehия 1-фehил-3-haфtaлehилokcипpoпahamиhob или иx фapmakoлoгичeckи пpиemлemыx kиcлotho-aддиtиbhыx coлeй
HUT59394A (en) Process for producing piperazine derivatives and pharmaceutical compositions comprising same
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
EP0228845A3 (en) N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same
ZA891389B (en) L-amino-3-acylquinoline derivatives their use as inhibitors of gastric secretion
EG18231A (en) A process for the preparation of pharmaceutical compounds
IL86080A0 (en) Bicyclic compounds,processes for preparation thereof and pharmaceutical composition comprising the same
DE3882438D1 (de) Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
HU895050D0 (en) Process for the production of new beta-diketones, their medically useful salts, esters, and medical preparations containing the beta diketones
EP0446921A3 (en) Optically active alkylene-dioxybenzene derivatives and their use in therapy
ES8602764A1 (es) Un procedimiento para preparar derivados de tiadiazina
HU913293D0 (en) Process for the production of pierazine derivatives and medical preparations containing them
MY102275A (en) Antimykotische aminoazole ii
HUT43930A (en) Fungicides comprising naphthimidazolone derivatives as active substance and process for preparing the active substance
KR840008012A (ko) 아미노에틸-피리딘 및 -피라진유도체의 제조방법
GR3000488T3 (en) Novel 1,4-dihydropyridines containing fluorine, process for their preparation and their use as medicaments
ES2002113A6 (es) Procedimiento para la preparacion de derivados de 1-alquil-ergolinil-tiourea
PT87954A (pt) Processo para a preparacao de composicoes farmaceuticas contendo derivados de dioxopiperidina, com efeito antipsicotico
ES479804A1 (es) Un procedimiento para la preparacion de derivados del acido amino-desoxi-clavulanico.
HU896163D0 (en) Process for the preparation of triazolylthioamide derivatives

Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960630