PT75440B - Preparation process of n-<2-<<<<5-(dimethylamino)-methyl-2-furanyl>-methyl>>-thio-ethyl>-n'-(3,4-methylenedioxidebenzyl)-2-n itro-1,1-ethenediamine with anti-ulcerous activity and pharm aceutic compositions therewith - Google Patents

Preparation process of n-<2-<<<<5-(dimethylamino)-methyl-2-furanyl>-methyl>>-thio-ethyl>-n'-(3,4-methylenedioxidebenzyl)-2-n itro-1,1-ethenediamine with anti-ulcerous activity and pharm aceutic compositions therewith

Info

Publication number
PT75440B
PT75440B PT75440A PT7544082A PT75440B PT 75440 B PT75440 B PT 75440B PT 75440 A PT75440 A PT 75440A PT 7544082 A PT7544082 A PT 7544082A PT 75440 B PT75440 B PT 75440B
Authority
PT
Portugal
Prior art keywords
methyl
methylenedioxidebenzyl
aceutic
ethenediamine
itro
Prior art date
Application number
PT75440A
Other languages
English (en)
Other versions
PT75440A (en
Original Assignee
Ausonia Farma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11208027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT75440(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ausonia Farma Srl filed Critical Ausonia Farma Srl
Publication of PT75440A publication Critical patent/PT75440A/pt
Publication of PT75440B publication Critical patent/PT75440B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT75440A 1981-08-18 1982-08-18 Preparation process of n-<2-<<<<5-(dimethylamino)-methyl-2-furanyl>-methyl>>-thio-ethyl>-n'-(3,4-methylenedioxidebenzyl)-2-n itro-1,1-ethenediamine with anti-ulcerous activity and pharm aceutic compositions therewith PT75440B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/81A IT1168163B (it) 1981-08-18 1981-08-18 Composto ad attivita' antiulcera, procedimento per la sua preparazione e composizioni farmaceutiche relative

Publications (2)

Publication Number Publication Date
PT75440A PT75440A (en) 1982-09-01
PT75440B true PT75440B (en) 1986-02-04

Family

ID=11208027

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75440A PT75440B (en) 1981-08-18 1982-08-18 Preparation process of n-<2-<<<<5-(dimethylamino)-methyl-2-furanyl>-methyl>>-thio-ethyl>-n'-(3,4-methylenedioxidebenzyl)-2-n itro-1,1-ethenediamine with anti-ulcerous activity and pharm aceutic compositions therewith

Country Status (23)

Country Link
US (1) US4431664A (pt)
JP (1) JPS5859982A (pt)
KR (1) KR860000851B1 (pt)
AR (1) AR230444A1 (pt)
AT (1) AT383597B (pt)
AU (1) AU533719B2 (pt)
BE (1) BE894093A (pt)
CA (1) CA1182121A (pt)
CH (1) CH650259A5 (pt)
DE (1) DE3230265C2 (pt)
DK (1) DK156067C (pt)
ES (1) ES515068A0 (pt)
FR (1) FR2511675A1 (pt)
GB (1) GB2104071B (pt)
GR (1) GR76260B (pt)
IT (1) IT1168163B (pt)
LU (1) LU84340A1 (pt)
NL (1) NL186447C (pt)
NO (1) NO159448C (pt)
PH (1) PH19228A (pt)
PT (1) PT75440B (pt)
SE (1) SE448456B (pt)
ZA (1) ZA825718B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1175808B (it) * 1984-03-07 1987-07-15 Ausonia Farma Srl Procedimento per la preparazione di composto con attivita' antiulcera
IT1196133B (it) * 1984-06-06 1988-11-10 Ausonia Farma Srl Derivati furanici con attivita' antiulcera
AU7235287A (en) * 1986-03-28 1987-10-20 Janus Farmaceutici S.R.L Synthesis of antiulcer compounds
GB8907700D0 (en) * 1989-04-05 1989-05-17 Fine Organics Ltd Preparation of substituted ethenes
JPH0416036U (pt) * 1990-05-31 1992-02-10

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140681A (en) * 1974-11-08 1979-02-20 Mitsubishi Chemical Industries, Limited N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
IT1168163B (it) 1987-05-20
SE448456B (sv) 1987-02-23
CA1182121A (en) 1985-02-05
NL186447C (nl) 1990-12-03
PT75440A (en) 1982-09-01
JPS6335631B2 (pt) 1988-07-15
AR230444A1 (es) 1984-04-30
NL186447B (nl) 1990-07-02
DE3230265C2 (de) 1984-09-20
ES8306372A1 (es) 1983-06-01
FR2511675B1 (pt) 1984-02-10
ZA825718B (en) 1983-06-29
JPS5859982A (ja) 1983-04-09
AU533719B2 (en) 1983-12-08
KR840001162A (ko) 1984-03-28
AU8673182A (en) 1983-02-24
CH650259A5 (it) 1985-07-15
SE8204670D0 (sv) 1982-08-12
DK156067B (da) 1989-06-19
GR76260B (pt) 1984-08-04
DE3230265A1 (de) 1983-03-03
SE8204670L (sv) 1983-02-19
PH19228A (en) 1986-02-12
GB2104071A (en) 1983-03-02
ES515068A0 (es) 1983-06-01
NL8203160A (nl) 1983-03-16
ATA312282A (de) 1986-12-15
DK156067C (da) 1989-12-04
DK357182A (da) 1983-02-19
GB2104071B (en) 1985-03-27
IT8123546A0 (it) 1981-08-18
NO159448C (no) 1988-12-28
LU84340A1 (fr) 1983-02-28
NO159448B (no) 1988-09-19
KR860000851B1 (ko) 1986-07-09
NO822801L (no) 1983-02-21
US4431664A (en) 1984-02-14
BE894093A (nl) 1982-12-01
FR2511675A1 (fr) 1983-02-25
AT383597B (de) 1987-07-27

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