DK156067C - Analogifremgangsmaade til fremstilling af n-(2-((5-(dimethylamino-methyl)-2-furanyl)-methylthio)-ethyl)-n'-(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin - Google Patents

Analogifremgangsmaade til fremstilling af n-(2-((5-(dimethylamino-methyl)-2-furanyl)-methylthio)-ethyl)-n'-(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin

Info

Publication number
DK156067C
DK156067C DK357182A DK357182A DK156067C DK 156067 C DK156067 C DK 156067C DK 357182 A DK357182 A DK 357182A DK 357182 A DK357182 A DK 357182A DK 156067 C DK156067 C DK 156067C
Authority
DK
Denmark
Prior art keywords
methylendioxybenzyl
eth
furanyl
methylthio
dimethylamino
Prior art date
Application number
DK357182A
Other languages
English (en)
Other versions
DK357182A (da
DK156067B (da
Inventor
Leonardo De Vincentiis
Original Assignee
Janus Farma Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11208027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK156067(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janus Farma Srl filed Critical Janus Farma Srl
Publication of DK357182A publication Critical patent/DK357182A/da
Publication of DK156067B publication Critical patent/DK156067B/da
Application granted granted Critical
Publication of DK156067C publication Critical patent/DK156067C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK357182A 1981-08-18 1982-08-09 Analogifremgangsmaade til fremstilling af n-(2-((5-(dimethylamino-methyl)-2-furanyl)-methylthio)-ethyl)-n'-(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin DK156067C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT23546/81A IT1168163B (it) 1981-08-18 1981-08-18 Composto ad attivita' antiulcera, procedimento per la sua preparazione e composizioni farmaceutiche relative
IT2354681 1981-08-18

Publications (3)

Publication Number Publication Date
DK357182A DK357182A (da) 1983-02-19
DK156067B DK156067B (da) 1989-06-19
DK156067C true DK156067C (da) 1989-12-04

Family

ID=11208027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK357182A DK156067C (da) 1981-08-18 1982-08-09 Analogifremgangsmaade til fremstilling af n-(2-((5-(dimethylamino-methyl)-2-furanyl)-methylthio)-ethyl)-n'-(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin

Country Status (23)

Country Link
US (1) US4431664A (da)
JP (1) JPS5859982A (da)
KR (1) KR860000851B1 (da)
AR (1) AR230444A1 (da)
AT (1) AT383597B (da)
AU (1) AU533719B2 (da)
BE (1) BE894093A (da)
CA (1) CA1182121A (da)
CH (1) CH650259A5 (da)
DE (1) DE3230265C2 (da)
DK (1) DK156067C (da)
ES (1) ES515068A0 (da)
FR (1) FR2511675A1 (da)
GB (1) GB2104071B (da)
GR (1) GR76260B (da)
IT (1) IT1168163B (da)
LU (1) LU84340A1 (da)
NL (1) NL186447C (da)
NO (1) NO159448C (da)
PH (1) PH19228A (da)
PT (1) PT75440B (da)
SE (1) SE448456B (da)
ZA (1) ZA825718B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1175808B (it) * 1984-03-07 1987-07-15 Ausonia Farma Srl Procedimento per la preparazione di composto con attivita' antiulcera
IT1196133B (it) * 1984-06-06 1988-11-10 Ausonia Farma Srl Derivati furanici con attivita' antiulcera
KR950009825B1 (ko) * 1986-03-28 1995-08-29 자누스 화마스티씨 에스.알.엘. 치료학적 항궤양 활성이 있는 니페로티딘의 합성방법
GB8907700D0 (en) * 1989-04-05 1989-05-17 Fine Organics Ltd Preparation of substituted ethenes
JPH0416036U (da) * 1990-05-31 1992-02-10

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4140681A (en) * 1974-11-08 1979-02-20 Mitsubishi Chemical Industries, Limited N2 -Arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU533719B2 (en) 1983-12-08
PT75440A (en) 1982-09-01
DE3230265A1 (de) 1983-03-03
ZA825718B (en) 1983-06-29
FR2511675B1 (da) 1984-02-10
AT383597B (de) 1987-07-27
KR860000851B1 (ko) 1986-07-09
AR230444A1 (es) 1984-04-30
ATA312282A (de) 1986-12-15
SE8204670D0 (sv) 1982-08-12
GB2104071B (en) 1985-03-27
AU8673182A (en) 1983-02-24
ES8306372A1 (es) 1983-06-01
CH650259A5 (it) 1985-07-15
DK357182A (da) 1983-02-19
NL8203160A (nl) 1983-03-16
PH19228A (en) 1986-02-12
GR76260B (da) 1984-08-04
US4431664A (en) 1984-02-14
NO159448C (no) 1988-12-28
NL186447C (nl) 1990-12-03
NL186447B (nl) 1990-07-02
NO159448B (no) 1988-09-19
BE894093A (nl) 1982-12-01
NO822801L (no) 1983-02-21
PT75440B (en) 1986-02-04
ES515068A0 (es) 1983-06-01
JPS6335631B2 (da) 1988-07-15
SE8204670L (sv) 1983-02-19
IT1168163B (it) 1987-05-20
KR840001162A (ko) 1984-03-28
JPS5859982A (ja) 1983-04-09
LU84340A1 (fr) 1983-02-28
FR2511675A1 (fr) 1983-02-25
SE448456B (sv) 1987-02-23
GB2104071A (en) 1983-03-02
DK156067B (da) 1989-06-19
CA1182121A (en) 1985-02-05
IT8123546A0 (it) 1981-08-18
DE3230265C2 (de) 1984-09-20

Similar Documents

Publication Publication Date Title
DK160940C (da) Analogifremgangsmaade til fremstilling af benzoheterocycliske forbindelser eller farmaceutisk acceptable salte deraf
DK149850C (da) Analogifremgangsmaade til fremstilling af 5-(3,4-disubst. phenyl)-oxazolidinoner eller thiazolidinoner eller de tilsvarende thioner
DK156067C (da) Analogifremgangsmaade til fremstilling af n-(2-((5-(dimethylamino-methyl)-2-furanyl)-methylthio)-ethyl)-n'-(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin
DK150902C (da) Analogifremgangsmaade til fremstilling af n-(3-alkylaminopropyl)-n'-(disubstitueret)-phenylurinstoffer
DK152115C (da) Analogifremgangsmaade til fremstilling af fluorerede 2,5-diamino-3-pentenderivater og farmaceutisk acceptable salte deraf
DK162046C (da) Analogifremgangsmaade til fremstilling af 2-(halogensubstitueret phenyl)-2-chlor-1-(1h-1,2,4-triazol-1-yl)-omega,omega,omega-trifluoralkan-forbindelse eller farmaceutisk acceptable syreadditionssalte deraf
AR230631A1 (es) Procedimiento para preparar nuevos derivados de 5-(4,5-dihidro-3(2h)-piridazinon-6-il)-benzotriazol
ES502121A0 (es) Metodo para la preparacion de n-(2-(((5-dialquilamino)-me- til-2-metil-2-furanil)-metil)-etil)-n'alquil-2-nitro-1,1- etendiamina
DK155978C (da) Fremgangsmaade til stabilisering af 4-methyl-5-(2'-chlorethyl)thiazol
DK157494C (da) Fremgangsmaade til fremstilling af n-(2(((5-((dimethylamino)-methyl)-2-furanyl)methyl)thio)ethyl)-n'(3,4-methylendioxybenzyl)-2-nitro-1,1-ethendiamin
AR225940A1 (es) Un procedimiento para preparar la n-(2-((5-(dimetilamino)metil)-2-furanilmetil)tio)etil)-n'-metil-2-nitro-1,1-etenodiamina
IT1167794B (it) Procedimento per la preparazione del n-(2-(((5-(dimetilamino)-metil-2-furanil)-metil)-tio)-etil)-n'-metil-2-nitro-1,1 etendiamina
ES497737A0 (es) Procedimiento para la obtencion de la n-(2-((5-((dimetilami-no)metil)furfuril)tio)etil)-n'- metil -2- nitro-1,1- eteno- diamina
DK157923C (da) Analogifremgangsmaade til fremstilling af nae-cyano-n-(1-oxido-4-pyridyl)-n'-1,2,2-trimethylpropylguanidin eller salte deraf med farmaceutisk acceptable syrer
NO821668L (no) Fremgangsmaate ved fremstilling av n-(arylthioalkyl)-n`-(aminoalkyl)-ureaderivater
ES497386A0 (es) Procedimiento para la obtencion de la n-(2-( ( (5-( (dimeti-lamino)metil)-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1-etenodiamina
IT1149947B (it) Procedimento di preparazione della n-(2-(((5-(dimetilamino)-metil-2-flranil)-metil)-tio)-etil)-n'-metil-2-nitro-1,1-etilendiamina
DK157996C (da) Analogifremgangsmaade til fremstilling af 5-(2-alkoxyphenyl)-hydantoinderivater eller farmaceutisk acceptable salte deraf
ES543966A0 (es) Procedimiento para la preparacion de la n-(2-(((5-(dimetila-mino)-metil-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1- etendiamina
ES504463A0 (es) Procedimiento para la obtencion de la n-(2-(((5-(dimetilami-no)metil)-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1- etenodiamina
DK149214C (da) Analogifremgangsmaade til fremstilling af 2-(3-methyl-2-butenyl)-n,n'- diphenylmalonomonohydrazid eller farmaceutisk acceptable salte deraf
AT386200B (de) Verfahren zur herstellung von n-(2-(((5-(dimethyl-amino)-methyl-2-furanyl)met yl)thio)-aethyl)-n' -methyl-2-nitro-1,1-aethendiamin
IT1169237B (it) Metodo per l'isolamento e la purificazione della n-(2-(((5-(dimetilamino)-metil-2-furanil)-metil)-tio)-etil)-n'-metil-2-nitro-1,1-etendiamina
MX154876A (es) Procedimiento para la preparacion de n-(2-(((5-(dimetilamino)-metil-2-furanil)-metil)-tio)etil)-(n'-(3,4-metilendioxibencil)-2-nitro-1-1-etendiamina
IT1167489B (it) Procedimento per la preparazione della n-(2-(((5-(dimetilamino)-metil-2-furil)-metil)-tio)-)n'-metil-2-nitro-1,1-etilendiamina

Legal Events

Date Code Title Description
PBP Patent lapsed