PT75352B - Process for the preparation of 1-phenyl-2-amino carbonyl-indol compounds useful as medicines and of the intermidiate products thereof - Google Patents

Process for the preparation of 1-phenyl-2-amino carbonyl-indol compounds useful as medicines and of the intermidiate products thereof

Info

Publication number
PT75352B
PT75352B PT75352A PT7535282A PT75352B PT 75352 B PT75352 B PT 75352B PT 75352 A PT75352 A PT 75352A PT 7535282 A PT7535282 A PT 7535282A PT 75352 B PT75352 B PT 75352B
Authority
PT
Portugal
Prior art keywords
radical
compounds
lower alkyl
hydrogen atom
phenyl
Prior art date
Application number
PT75352A
Other languages
English (en)
Other versions
PT75352A (en
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of PT75352A publication Critical patent/PT75352A/pt
Publication of PT75352B publication Critical patent/PT75352B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
PT75352A 1981-08-08 1982-07-30 Process for the preparation of 1-phenyl-2-amino carbonyl-indol compounds useful as medicines and of the intermidiate products thereof PT75352B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813131527 DE3131527A1 (de) 1981-08-08 1981-08-08 1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
PT75352A PT75352A (en) 1982-08-01
PT75352B true PT75352B (en) 1984-08-01

Family

ID=6138966

Family Applications (1)

Application Number Title Priority Date Filing Date
PT75352A PT75352B (en) 1981-08-08 1982-07-30 Process for the preparation of 1-phenyl-2-amino carbonyl-indol compounds useful as medicines and of the intermidiate products thereof

Country Status (21)

Country Link
US (2) US4803198A (pt)
EP (1) EP0071935B1 (pt)
JP (1) JPS58159459A (pt)
AT (1) ATE16478T1 (pt)
AU (1) AU554976B2 (pt)
CA (1) CA1189859A (pt)
DD (1) DD202542A5 (pt)
DE (2) DE3131527A1 (pt)
DK (1) DK156569B (pt)
ES (4) ES514816A0 (pt)
FI (1) FI76073C (pt)
GR (1) GR76804B (pt)
HU (1) HU186962B (pt)
IE (1) IE53646B1 (pt)
IL (1) IL66485A (pt)
NO (1) NO156526C (pt)
NZ (1) NZ201514A (pt)
PH (1) PH18886A (pt)
PT (1) PT75352B (pt)
SU (2) SU1195903A3 (pt)
ZA (1) ZA825667B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3304019A1 (de) * 1983-02-07 1984-08-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 3-acyloxy-1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4675332A (en) * 1984-12-10 1987-06-23 Warner-Lambert Company Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents
US5047402A (en) * 1988-04-13 1991-09-10 Ici Americas Inc. Cyclic amides as medicaments
US5395817A (en) * 1992-01-22 1995-03-07 Imperial Chemical Industries Plc N-arylindoles and their use as herbicides
US5599774A (en) * 1992-01-22 1997-02-04 Imperial Chemical Industries Plc N-arylindoles and their use as herbicides
ZA939516B (en) * 1992-12-22 1994-06-06 Smithkline Beecham Corp Endothelin receptor antagonists
US5424329A (en) * 1993-08-18 1995-06-13 Warner-Lambert Company Indole-2-carboxamides as inhibitors of cell adhesion
US5686481A (en) * 1993-12-21 1997-11-11 Smithkline Beecham Corporation Endothelin receptor antagonists
US5684032A (en) * 1994-12-13 1997-11-04 Smithkline Beecham Corporation Compounds
DE19532054A1 (de) * 1995-08-31 1997-03-06 Hoechst Ag Verfahren zur Herstellung von N-Carboxymethylen-4-chlor-anthranilsäure, sowie deren Dialkylestern
KR100546477B1 (ko) * 1997-05-09 2006-01-26 하. 룬트벡 아크티에 셀스카브 세르틴돌의 제조방법
SG183699A1 (en) * 2007-08-10 2012-09-27 Lundbeck & Co As H Heteroaryl amide analogues
AU2016258192B2 (en) 2015-05-06 2021-07-29 Leidos Biomedical Research, Inc. K-Ras modulators
WO2018195439A2 (en) 2017-04-20 2018-10-25 The Regents Of The University Of California K-ras modulators

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE158089C (pt) *
DE105495C (pt) *
BE439918A (pt) * 1939-11-29
FR869014A (fr) * 1941-01-04 1942-01-22 Telefunken Gmbh Perfectionnements aux systèmes de concentration de rayons électroniques
US3198807A (en) * 1961-07-25 1965-08-03 Substitutes carboxamide indoles and indolines
DE1720033A1 (de) * 1966-03-02 1971-05-19 Yoshitomi Pharmaceutical Neue Indolderivate und Verfahren zu ihrer Herstellung
NL133069C (pt) * 1966-07-29
DE1643262C3 (de) * 1967-12-13 1975-06-26 C.H. Boehringer Sohn, 6507 Ingelheim i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3634402A (en) * 1968-04-26 1972-01-11 Sumitomo Chemical Co Process for producing 1 4-benzodiazepine derivatives and their salts
FR2260332A1 (en) * 1974-02-12 1975-09-05 Delalande Sa 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity
US4196143A (en) * 1974-07-01 1980-04-01 The Dow Chemical Company Substituted phenoxyalkyl quaternary ammonium compounds
US4175083A (en) * 1975-09-08 1979-11-20 Warner-Lambert Company Indolopyrones having antiallergic activity
US4059583A (en) * 1975-11-13 1977-11-22 Mcneil Laboratories, Incorporated Substituted indoles
DE2931323A1 (de) * 1979-08-02 1981-02-26 Kali Chemie Pharma Gmbh Neue n-aminoalkylindol-derivate und ihre salze
DE3304019A1 (de) * 1983-02-07 1984-08-09 Kali-Chemie Pharma Gmbh, 3000 Hannover 3-acyloxy-1-phenyl-2-aminocarbonylindol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
US4924004A (en) 1990-05-08
EP0071935B1 (de) 1985-11-13
ES523269A0 (es) 1984-03-16
GR76804B (pt) 1984-09-04
IL66485A0 (en) 1982-12-31
HU186962B (en) 1985-10-28
ZA825667B (en) 1983-06-29
FI76073B (fi) 1988-05-31
CA1189859A (en) 1985-07-02
AU554976B2 (en) 1986-09-11
ES8404854A1 (es) 1984-05-16
NO156526B (no) 1987-06-29
PH18886A (en) 1985-10-25
NZ201514A (en) 1985-09-13
JPH0244306B2 (pt) 1990-10-03
US4803198A (en) 1989-02-07
JPS58159459A (ja) 1983-09-21
ATE16478T1 (de) 1985-11-15
SU1195903A3 (ru) 1985-11-30
AU8696182A (en) 1983-02-17
DE3267429D1 (en) 1985-12-19
ES8403478A1 (es) 1984-03-16
DD202542A5 (de) 1983-09-21
IE821896L (en) 1983-02-08
ES8400403A1 (es) 1983-10-16
PT75352A (en) 1982-08-01
EP0071935A2 (de) 1983-02-16
NO156526C (no) 1987-10-07
FI76073C (fi) 1988-09-09
DK352482A (da) 1983-02-09
IE53646B1 (en) 1989-01-04
DE3131527A1 (de) 1983-02-24
ES523267A0 (es) 1984-03-16
DK156569B (da) 1989-09-11
SU1223843A3 (ru) 1986-04-07
IL66485A (en) 1985-11-29
FI822722L (fi) 1983-02-09
FI822722A0 (fi) 1982-08-05
ES523268A0 (es) 1984-05-16
ES8403479A1 (es) 1984-03-16
NO822693L (no) 1983-02-09
ES514816A0 (es) 1983-10-16
EP0071935A3 (en) 1983-08-17

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