PT65027B - Process for the preparation of new anorexic compounds or piperazinyl pyrazines - Google Patents
Process for the preparation of new anorexic compounds or piperazinyl pyrazinesInfo
- Publication number
- PT65027B PT65027B PT65027A PT6502776A PT65027B PT 65027 B PT65027 B PT 65027B PT 65027 A PT65027 A PT 65027A PT 6502776 A PT6502776 A PT 6502776A PT 65027 B PT65027 B PT 65027B
- Authority
- PT
- Portugal
- Prior art keywords
- anorexic
- compounds
- preparation
- new
- pyrazines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57005275A | 1975-04-21 | 1975-04-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT65027A PT65027A (en) | 1976-05-01 |
| PT65027B true PT65027B (en) | 1978-04-03 |
Family
ID=24277994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT65027A PT65027B (en) | 1975-04-21 | 1976-04-21 | Process for the preparation of new anorexic compounds or piperazinyl pyrazines |
Country Status (36)
| Country | Link |
|---|---|
| JP (1) | JPS51136688A (es) |
| AR (1) | AR210349A1 (es) |
| AT (1) | AT353795B (es) |
| AU (1) | AU496854B2 (es) |
| BE (1) | BE840904A (es) |
| BG (1) | BG34185A3 (es) |
| CA (1) | CA1059128A (es) |
| CH (1) | CH619462A5 (es) |
| CS (1) | CS195726B2 (es) |
| CY (1) | CY1090A (es) |
| DD (1) | DD124599A5 (es) |
| DE (1) | DE2617205C3 (es) |
| DK (1) | DK143899C (es) |
| EG (1) | EG12387A (es) |
| ES (4) | ES447150A1 (es) |
| FI (1) | FI62666C (es) |
| FR (1) | FR2308367A1 (es) |
| GB (1) | GB1492528A (es) |
| GR (1) | GR59900B (es) |
| HK (1) | HK60380A (es) |
| HU (1) | HU172684B (es) |
| IE (1) | IE42979B1 (es) |
| IL (1) | IL49391A (es) |
| KE (1) | KE3088A (es) |
| LU (1) | LU74795A1 (es) |
| MY (1) | MY8100225A (es) |
| NL (1) | NL167692C (es) |
| NO (1) | NO146599C (es) |
| PH (1) | PH12274A (es) |
| PL (1) | PL99664B1 (es) |
| PT (1) | PT65027B (es) |
| RO (1) | RO73278A (es) |
| SE (1) | SE421695B (es) |
| SU (1) | SU638260A3 (es) |
| YU (1) | YU100676A (es) |
| ZA (1) | ZA762320B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091098A (en) * | 1977-04-25 | 1978-05-23 | Merck & Co., Inc. | 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides |
| US4163849A (en) | 1978-03-17 | 1979-08-07 | Merck & Co., Inc. | Piperazinylpyrazines |
| US4252816A (en) * | 1979-12-03 | 1981-02-24 | Merck & Co., Inc. | Tetrahydro-1H-1,4-diazepino(1,7-a)benzimidazoles useful as analgesic agents |
| US4339579A (en) | 1980-12-29 | 1982-07-13 | American Home Products Corporation | 2,6-Bis-(pyrrolopyrazinyl)pyrazines |
| EP0094498A3 (en) * | 1982-05-06 | 1985-04-03 | American Cyanamid Company | Antiatherosclerotic 1-piperazine derivatives |
| US4547505A (en) * | 1983-03-25 | 1985-10-15 | Degussa Aktiengesellschaft | N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production |
| US4788290A (en) * | 1987-12-11 | 1988-11-29 | American Home Products Corporation | Serotonergic pyrazine derivatives |
| EP0580465A1 (fr) * | 1992-06-25 | 1994-01-26 | Sanofi | Nouvelle utilisation thérapeutique d'hétérocyclyl-pipérazines comme 5-HT3 agonistes et nouveaux dérivés |
| DE69842058D1 (de) * | 1997-10-27 | 2011-01-27 | Neurosearch As | Heteroaryl Diazacycloalkane als cholinergische Ligande für Nikotin-Acetylcholin-Rezeptoren |
| JP2002543070A (ja) | 1999-04-26 | 2002-12-17 | ニューロサーチ、アクティーゼルスカブ | ヘテロアリールジアザシクロアルカン類、その製造方法及びその使用方法 |
| KR20030031886A (ko) * | 2000-02-16 | 2003-04-23 | 뉴로젠 코포레이션 | 치환된 아릴피라진 |
| US6825198B2 (en) * | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
| SE0202287D0 (sv) * | 2002-07-19 | 2002-07-19 | Biovitrum Ab | New compounds |
| DK1534391T3 (da) | 2002-07-19 | 2007-06-11 | Biovitrum Ab | Nye piperazinyl-pyrazinonderivater til behandling af 5-HT2A-recptor-relaterede forstyrrelser |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2606906A (en) * | 1948-10-14 | 1952-08-12 | American Cyanamid Co | 1-(2-pyridyl) piperazine and process of preparing same |
-
1976
- 1976-04-07 SE SE7604093A patent/SE421695B/xx not_active IP Right Cessation
- 1976-04-07 DK DK164476A patent/DK143899C/da not_active IP Right Cessation
- 1976-04-07 EG EG76205A patent/EG12387A/xx active
- 1976-04-08 NO NO761207A patent/NO146599C/no unknown
- 1976-04-09 FI FI760978A patent/FI62666C/fi not_active IP Right Cessation
- 1976-04-09 NL NL7603800A patent/NL167692C/xx not_active IP Right Cessation
- 1976-04-12 IL IL49391A patent/IL49391A/xx unknown
- 1976-04-13 AU AU12966/76A patent/AU496854B2/en not_active Expired
- 1976-04-13 PH PH18329A patent/PH12274A/en unknown
- 1976-04-13 GR GR50538A patent/GR59900B/el unknown
- 1976-04-14 FR FR7610958A patent/FR2308367A1/fr active Granted
- 1976-04-14 CA CA250,732A patent/CA1059128A/en not_active Expired
- 1976-04-15 CY CY1090A patent/CY1090A/xx unknown
- 1976-04-15 GB GB15644/76A patent/GB1492528A/en not_active Expired
- 1976-04-15 DD DD192399A patent/DD124599A5/xx unknown
- 1976-04-16 CS CS762549A patent/CS195726B2/cs unknown
- 1976-04-19 JP JP51043763A patent/JPS51136688A/ja active Granted
- 1976-04-19 ES ES447150A patent/ES447150A1/es not_active Expired
- 1976-04-20 ZA ZA762320A patent/ZA762320B/xx unknown
- 1976-04-20 BG BG7632968A patent/BG34185A3/xx unknown
- 1976-04-20 PL PL1976188912A patent/PL99664B1/pl unknown
- 1976-04-20 BE BE166282A patent/BE840904A/xx not_active IP Right Cessation
- 1976-04-20 CH CH492676A patent/CH619462A5/de not_active IP Right Cessation
- 1976-04-20 AR AR262930A patent/AR210349A1/es active
- 1976-04-20 RO RO7685688A patent/RO73278A/ro unknown
- 1976-04-20 SU SU762346054A patent/SU638260A3/ru active
- 1976-04-20 DE DE2617205A patent/DE2617205C3/de not_active Expired
- 1976-04-20 AT AT288376A patent/AT353795B/de not_active IP Right Cessation
- 1976-04-20 YU YU01006/76A patent/YU100676A/xx unknown
- 1976-04-20 LU LU74795A patent/LU74795A1/xx unknown
- 1976-04-21 HU HU76ME00001967A patent/HU172684B/hu unknown
- 1976-04-21 PT PT65027A patent/PT65027B/pt unknown
- 1976-04-21 IE IE828/76A patent/IE42979B1/en unknown
-
1977
- 1977-06-01 ES ES459405A patent/ES459405A1/es not_active Expired
- 1977-06-01 ES ES459406A patent/ES459406A1/es not_active Expired
- 1977-06-01 ES ES459407A patent/ES459407A1/es not_active Expired
-
1980
- 1980-10-02 KE KE3088A patent/KE3088A/xx unknown
- 1980-10-30 HK HK603/80A patent/HK60380A/xx unknown
-
1981
- 1981-12-30 MY MY225/81A patent/MY8100225A/xx unknown
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