PT641861E - Processo de producao de polipeptidos proteinas ou peptidos hidrofobicos - Google Patents
Processo de producao de polipeptidos proteinas ou peptidos hidrofobicosInfo
- Publication number
- PT641861E PT641861E PT94109676T PT94109676T PT641861E PT 641861 E PT641861 E PT 641861E PT 94109676 T PT94109676 T PT 94109676T PT 94109676 T PT94109676 T PT 94109676T PT 641861 E PT641861 E PT 641861E
- Authority
- PT
- Portugal
- Prior art keywords
- proteins
- peptides
- production
- polyepeptides
- hydrofobic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93110755 | 1993-07-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT641861E true PT641861E (pt) | 2003-07-31 |
Family
ID=8213046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT94109676T PT641861E (pt) | 1993-07-06 | 1994-06-23 | Processo de producao de polipeptidos proteinas ou peptidos hidrofobicos |
Country Status (14)
Country | Link |
---|---|
US (1) | US5750374A (pt) |
EP (2) | EP1304381A3 (pt) |
JP (2) | JP2947401B2 (pt) |
CN (3) | CN1057535C (pt) |
AT (1) | ATE236984T1 (pt) |
AU (1) | AU666274B2 (pt) |
CA (1) | CA2125467C (pt) |
DE (1) | DE69432449T2 (pt) |
DK (1) | DK0641861T3 (pt) |
ES (1) | ES2194017T3 (pt) |
NZ (1) | NZ260907A (pt) |
PT (1) | PT641861E (pt) |
RU (1) | RU94023251A (pt) |
ZA (1) | ZA944686B (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6303567B1 (en) | 1995-03-14 | 2001-10-16 | Praecis Pharmaceuticals, Inc . | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
US5817626A (en) * | 1995-03-14 | 1998-10-06 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation |
ES2175083T3 (es) | 1995-03-14 | 2002-11-16 | Praecis Pharm Inc | Moduladores de la agregacion de amiloides. |
US5854215A (en) * | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals Incorporated | Modulators of β-amyloid peptide aggregation |
GB9618952D0 (en) | 1996-09-11 | 1996-10-23 | Sandoz Ltd | Process |
US6277826B1 (en) | 1996-08-27 | 2001-08-21 | Praecis Pharmaceuticals, Inc. | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
US5985242A (en) * | 1995-10-27 | 1999-11-16 | Praecis Pharmaceuticals, Inc. | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
PT1161449E (pt) | 1999-03-04 | 2007-10-12 | Praecis Pharm Inc | Moduladores de agregação do péptido beta-amilóide compreendendo d-aminoácidos |
AU5602100A (en) * | 1999-06-09 | 2000-12-28 | Arch Development Corporation | Recombinant prion-like genes and proteins and materials and methods comprising same |
WO2001029225A1 (en) * | 1999-10-21 | 2001-04-26 | Panorama Research, Inc. | A general method for optimizing the expression of heterologous proteins |
US7799561B2 (en) * | 2002-06-12 | 2010-09-21 | Sigma-Aldrich, Co. | Affinity peptides and method for purification of recombinant proteins |
FR2859221B1 (fr) * | 2003-08-28 | 2005-10-14 | Centre Nat Rech Scient | Vecteur de co-expression de domaines membranaires de proteines d'enveloppe d'un virus et utilisations |
US7741053B2 (en) * | 2005-05-13 | 2010-06-22 | Sigma-Aldrich Co. | Processes for purification of recombinant proteins |
KR100621354B1 (ko) * | 2005-06-14 | 2006-09-08 | 광주과학기술원 | 유비퀴틴을 이용한 아밀로이드-베타 펩티드의 제조방법 |
WO2010063460A1 (en) * | 2008-12-02 | 2010-06-10 | Universität Zürich | Recombinant production of hydrophobic peptides and fusion proteins for use in producing same |
JPWO2016047794A1 (ja) * | 2014-09-26 | 2017-09-28 | 株式会社カネカ | 疎水性ペプチドの製造法 |
JP6817939B2 (ja) | 2014-12-01 | 2021-01-20 | フェネックス インク. | ペプチド産生のための融合パートナー |
CN105001307B (zh) | 2015-07-31 | 2016-08-24 | 南京斯拜科生化实业有限公司 | 一种溶解难溶多肽的偶联肽链及其在液相色谱中分离纯化的应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0207044A1 (en) * | 1985-06-20 | 1986-12-30 | Monsanto Company | Release of peptides from polypeptides |
EP0212532A1 (en) * | 1985-08-12 | 1987-03-04 | Syntex (U.S.A.) Inc. | Method for producing fusion proteins |
JPS63502904A (ja) * | 1986-03-24 | 1988-10-27 | オ−ソ・フア−マシユ−チカル・コ−ポレ−シヨン | 合成htlv−3ペプチド、その組成物及び用途 |
CA1304886C (en) * | 1986-07-10 | 1992-07-07 | Heinz Dobeli | Metal chelate resins |
US5047513A (en) * | 1986-07-10 | 1991-09-10 | Hoffmann-La Roche Inc. | Metal chelate resins |
CA1329124C (en) * | 1987-02-02 | 1994-05-03 | Jerald C. Sadoff | Conjugate malaria vaccine |
CA1340522C (en) * | 1987-03-10 | 1999-05-04 | Heinz Dobeli | Fusion proteins containing neighbouring histidines for improved purification |
US5416007A (en) * | 1987-03-20 | 1995-05-16 | Creative Biomolecules, Inc. | Enhanced proteolytic cleavage of recombinant fusion proteins |
US5124255A (en) * | 1988-03-11 | 1992-06-23 | Abbott Laboratories | CKS method of protein synthesis |
IT1226728B (it) * | 1988-08-05 | 1991-02-05 | Eniricerche Spa | Coniugato peptidico immunologicamente attivo utile come vaccino antimalaria e metodo di immunizzazione impiegante lo stesso |
US5045190A (en) * | 1988-11-08 | 1991-09-03 | Carbonell Ruben G | Chromatography apparatus |
WO1991019810A1 (en) * | 1990-06-15 | 1991-12-26 | California Biotechnology Inc. | Transgenic non-human mammal displaying the amyloid-forming pathology of alzheimer's disease |
JPH06500560A (ja) * | 1990-08-24 | 1994-01-20 | プレジデント アンド フェローズ オブ ハーバード カレッジ | α―アンチキモトリプシン―β―タンパク質複合体形成妨害方法およびその方法に使用する合成ペプチド |
DK0770679T4 (da) * | 1990-11-03 | 2010-05-10 | Siemens Healthcare Diagnostics | HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf |
NZ243636A (en) * | 1991-07-29 | 1993-06-25 | Iaf Biochem Int | Immunoassay and kit for simultaneously detecting antibodies to hiv-1, hiv-2, htlv-1 and htlv-11 |
US5434050A (en) * | 1991-08-13 | 1995-07-18 | Regents Of The University Of Minnesota | Labelled β-amyloid peptide and methods of screening for Alzheimer's disease |
-
1994
- 1994-06-08 CA CA002125467A patent/CA2125467C/en not_active Expired - Fee Related
- 1994-06-23 PT PT94109676T patent/PT641861E/pt unknown
- 1994-06-23 AT AT94109676T patent/ATE236984T1/de not_active IP Right Cessation
- 1994-06-23 DK DK94109676T patent/DK0641861T3/da active
- 1994-06-23 ES ES94109676T patent/ES2194017T3/es not_active Expired - Lifetime
- 1994-06-23 DE DE69432449T patent/DE69432449T2/de not_active Expired - Fee Related
- 1994-06-23 EP EP03000052A patent/EP1304381A3/en not_active Withdrawn
- 1994-06-23 EP EP94109676A patent/EP0641861B1/en not_active Expired - Lifetime
- 1994-06-29 US US08/268,348 patent/US5750374A/en not_active Expired - Fee Related
- 1994-06-29 ZA ZA944686A patent/ZA944686B/xx unknown
- 1994-07-01 AU AU66122/94A patent/AU666274B2/en not_active Ceased
- 1994-07-01 NZ NZ260907A patent/NZ260907A/en not_active IP Right Cessation
- 1994-07-04 RU RU94023251/13A patent/RU94023251A/ru unknown
- 1994-07-04 CN CN94108110A patent/CN1057535C/zh not_active Expired - Fee Related
- 1994-07-04 CN CNA2006101006833A patent/CN1916017A/zh active Pending
- 1994-07-04 CN CNB99101393XA patent/CN100439391C/zh not_active Expired - Fee Related
- 1994-07-05 JP JP6153161A patent/JP2947401B2/ja not_active Expired - Fee Related
-
1998
- 1998-02-12 JP JP10030205A patent/JPH1143500A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ZA944686B (en) | 1995-01-06 |
EP1304381A3 (en) | 2003-05-02 |
DE69432449T2 (de) | 2004-04-08 |
EP0641861A2 (en) | 1995-03-08 |
RU94023251A (ru) | 1996-05-10 |
AU666274B2 (en) | 1996-02-01 |
EP1304381A2 (en) | 2003-04-23 |
DK0641861T3 (da) | 2003-07-28 |
JPH07102000A (ja) | 1995-04-18 |
CN1916017A (zh) | 2007-02-21 |
JP2947401B2 (ja) | 1999-09-13 |
EP0641861A3 (en) | 1997-07-30 |
CN1098416A (zh) | 1995-02-08 |
CN100439391C (zh) | 2008-12-03 |
CA2125467A1 (en) | 1995-01-07 |
CN1057535C (zh) | 2000-10-18 |
DE69432449D1 (de) | 2003-05-15 |
ES2194017T3 (es) | 2003-11-16 |
CN1227846A (zh) | 1999-09-08 |
JPH1143500A (ja) | 1999-02-16 |
EP0641861B1 (en) | 2003-04-09 |
AU6612294A (en) | 1995-01-27 |
ATE236984T1 (de) | 2003-04-15 |
US5750374A (en) | 1998-05-12 |
NZ260907A (en) | 1996-06-25 |
CA2125467C (en) | 2001-02-06 |
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