ATE189232T1 - Protein-s polypeptide und deren verwendungen - Google Patents

Protein-s polypeptide und deren verwendungen

Info

Publication number
ATE189232T1
ATE189232T1 AT92915841T AT92915841T ATE189232T1 AT E189232 T1 ATE189232 T1 AT E189232T1 AT 92915841 T AT92915841 T AT 92915841T AT 92915841 T AT92915841 T AT 92915841T AT E189232 T1 ATE189232 T1 AT E189232T1
Authority
AT
Austria
Prior art keywords
polypeptides
protein
useful
antibodies
c4bp
Prior art date
Application number
AT92915841T
Other languages
English (en)
Inventor
John H Griffin
Jose A Fernandez
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/907,190 external-priority patent/US5321123A/en
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE189232T1 publication Critical patent/ATE189232T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT92915841T 1991-07-02 1992-07-02 Protein-s polypeptide und deren verwendungen ATE189232T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72474691A 1991-07-02 1991-07-02
US07/907,190 US5321123A (en) 1991-07-02 1992-07-01 Protein S polypeptides and anti-peptide antibodies that inhibit protein S binding to C4B binding protein, diagnostic systems and therapeutic methods
PCT/US1992/005599 WO1993001209A1 (en) 1991-07-02 1992-07-02 Proteins s polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
ATE189232T1 true ATE189232T1 (de) 2000-02-15

Family

ID=27111033

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99202141T ATE350398T1 (de) 1991-07-02 1992-07-02 Protein s polypeptide und deren verwendungen
AT92915841T ATE189232T1 (de) 1991-07-02 1992-07-02 Protein-s polypeptide und deren verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT99202141T ATE350398T1 (de) 1991-07-02 1992-07-02 Protein s polypeptide und deren verwendungen

Country Status (10)

Country Link
EP (2) EP0592600B1 (de)
AT (2) ATE350398T1 (de)
AU (1) AU674496B2 (de)
CA (1) CA2112701C (de)
DE (2) DE69230614T2 (de)
DK (2) DK0592600T3 (de)
ES (2) ES2279598T3 (de)
GR (1) GR3033242T3 (de)
PT (1) PT592600E (de)
WO (1) WO1993001209A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863896A (en) * 1995-11-09 1999-01-26 Immuno Ag Evaluation of substances for altering and for increasing APC response
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
SE9604378D0 (sv) * 1996-11-27 1996-11-27 Tac Ab Methods and reagents for determining protein S
CA2522984A1 (en) * 2003-04-18 2004-10-28 Novartis Ag Methods and compositions targeting tyrosine kinases for the diagnosis and treatment of osteoarthritis
FR2863616A1 (fr) * 2003-12-12 2005-06-17 Stago Diagnostica Dosage de la proteine s libre non clivee par le facteur xa et utilisation de ce dosage pour l'evaluation du potentiel de coagulation
WO2007014749A2 (en) * 2005-07-29 2007-02-08 Universiteit Van Maastricht Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor
US20230174672A1 (en) * 2020-05-05 2023-06-08 Vega Therapeutics, Inc. Protein s antibodies, methods of making and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0271810B1 (de) * 1986-12-15 1994-03-09 Teijin Limited Immunologische Bestimmung von freiem menschlichem Protein-S und c4bp-Protein-S-Komplex
EP0315447A3 (de) * 1987-11-06 1990-07-18 Teijin Limited Verfahren zur immunologischen Bestimmung von humanem Protein S sowie Reagens und Kit dafür
JPH01231893A (ja) * 1988-03-14 1989-09-18 Fuji Yakuhin Kogyo Kk 抗ヒトプロテインsモノクローナル抗体およびその利用

Also Published As

Publication number Publication date
EP0592600A4 (de) 1994-10-12
EP0524737A3 (en) 1994-10-05
DE69230614T2 (de) 2000-06-21
AU674496B2 (en) 1997-01-02
EP0524737A2 (de) 1993-01-27
DK0972781T3 (da) 2007-03-05
EP0592600B1 (de) 2000-01-26
AU2323092A (en) 1993-02-11
CA2112701A1 (en) 1993-01-21
WO1993001209A1 (en) 1993-01-21
ES2279598T3 (es) 2007-08-16
ES2142317T3 (es) 2000-04-16
DE69233673T2 (de) 2007-10-04
DE69233673D1 (de) 2007-02-15
EP0592600A1 (de) 1994-04-20
ATE350398T1 (de) 2007-01-15
PT592600E (pt) 2000-05-31
DE69230614D1 (de) 2000-03-02
CA2112701C (en) 2007-09-25
GR3033242T3 (en) 2000-09-29
DK0592600T3 (da) 2000-04-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee