PT4194548T - Geração de células beta funcionais derivadas de células estaminais humanas pluripotentes, apresentando respiração mitocondrial dependente de glicose e resposta, em duas fases, de secreção de insulina - Google Patents

Geração de células beta funcionais derivadas de células estaminais humanas pluripotentes, apresentando respiração mitocondrial dependente de glicose e resposta, em duas fases, de secreção de insulina

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Publication number
PT4194548T
PT4194548T PT222130726T PT22213072T PT4194548T PT 4194548 T PT4194548 T PT 4194548T PT 222130726 T PT222130726 T PT 222130726T PT 22213072 T PT22213072 T PT 22213072T PT 4194548 T PT4194548 T PT 4194548T
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PT
Portugal
Prior art keywords
glucose
generation
stem cell
pluripotent stem
insulin secretion
Prior art date
Application number
PT222130726T
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English (en)
Portuguese (pt)
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Janssen Biotech Inc
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Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of PT4194548T publication Critical patent/PT4194548T/pt

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PT222130726T 2016-06-21 2017-06-14 Geração de células beta funcionais derivadas de células estaminais humanas pluripotentes, apresentando respiração mitocondrial dependente de glicose e resposta, em duas fases, de secreção de insulina PT4194548T (pt)

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US201662352968P 2016-06-21 2016-06-21

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CN118497104A (zh) 2017-11-15 2024-08-16 沃泰克斯药物股份有限公司 胰岛细胞制备性组合物和使用方法
EP3758719A4 (en) * 2018-03-02 2021-12-08 Vertex Pharmaceuticals Inc. METHODS FOR IMPROVING THE DIFFERENTIATION OF STEM CELLS INTO BETA CELLS
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CN112867497A (zh) * 2018-05-07 2021-05-28 哈佛学院校长同事会 与体外β细胞分化相关的细胞群和基因表达
EP3790956A4 (en) * 2018-05-11 2022-03-16 Cornell University METHOD FOR INDUCING DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS INTO MONOHORMONAL CELLS
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US10724052B2 (en) 2018-09-07 2020-07-28 Crispr Therapeutics Ag Universal donor cells
JP7555975B2 (ja) 2019-05-31 2024-09-25 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 生体適合性メンブレン複合体
WO2020243666A1 (en) 2019-05-31 2020-12-03 W. L. Gore & Associates, Inc. A biocompatible membrane composite
JP2022534545A (ja) 2019-05-31 2022-08-01 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 生体適合性メンブレン複合体
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