PT3491027T - Processo para a preparação e purificação do sal de sódio do ácido hialurónico - Google Patents
Processo para a preparação e purificação do sal de sódio do ácido hialurónicoInfo
- Publication number
- PT3491027T PT3491027T PT177555711T PT17755571T PT3491027T PT 3491027 T PT3491027 T PT 3491027T PT 177555711 T PT177555711 T PT 177555711T PT 17755571 T PT17755571 T PT 17755571T PT 3491027 T PT3491027 T PT 3491027T
- Authority
- PT
- Portugal
- Prior art keywords
- purification
- preparation
- sodium salt
- hyaluronic acid
- hyaluronic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Surgery (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Birds (AREA)
- Urology & Nephrology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102016000079633A IT201600079633A1 (it) | 2016-07-28 | 2016-07-28 | Procedimento di preparazione e purificazione del sale sodico dell’acido ialuronico |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3491027T true PT3491027T (pt) | 2020-08-24 |
Family
ID=57610222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT177555711T PT3491027T (pt) | 2016-07-28 | 2017-07-27 | Processo para a preparação e purificação do sal de sódio do ácido hialurónico |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10849925B2 (pt) |
| EP (1) | EP3491027B1 (pt) |
| JP (1) | JP6980974B2 (pt) |
| KR (1) | KR102391110B1 (pt) |
| CN (1) | CN109563178B (pt) |
| AU (1) | AU2017304290B2 (pt) |
| CA (1) | CA3030243A1 (pt) |
| EA (1) | EA039615B1 (pt) |
| ES (1) | ES2811101T3 (pt) |
| HU (1) | HUE050414T2 (pt) |
| IT (1) | IT201600079633A1 (pt) |
| PL (1) | PL3491027T3 (pt) |
| PT (1) | PT3491027T (pt) |
| WO (1) | WO2018020458A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201800009444A1 (it) | 2018-10-15 | 2020-04-15 | Fidia Farm Spa | Coniugati tra acido ialuronico e amminobisfosfonati e loro impiego terapeutico |
| IT201800009731A1 (it) | 2018-10-25 | 2020-04-25 | Fidia Farm Spa | Coniugato paclitaxel - acido ialuronico nel trattamento del carcinoma vescicale non infiltrante |
| IT201900019762A1 (it) | 2019-10-24 | 2021-04-24 | Fidia Farm Spa | Composizione farmaceutica per uso nel trattamento della cistite di varia eziologia |
| IT202000005692A1 (it) | 2020-03-17 | 2021-09-17 | Fidia Farm Spa | Bio-inchiostro per stampa 3D, relativo coniugato e processo di preparazione di un intermedio costituito da un linker fotoreattivo |
| IT202000007747A1 (it) | 2020-04-10 | 2021-10-10 | Fidia Farm Spa | Coniugato acido ialuronico-paclitaxel nel trattamento del mesotelioma |
| IT202000008209A1 (it) | 2020-04-17 | 2021-10-17 | Fidia Farm Spa | Procedimento di sintesi di un coniugato acido ialuronico-paclitaxel |
| IT202000014017A1 (it) | 2020-06-11 | 2021-12-11 | Fidia Farm Spa | Nuovi derivati ottenuti da acido ialuronico e carnosina |
| IT202000032243A1 (it) | 2020-12-23 | 2022-06-23 | Fidia Farm Spa | Nuovi agenti antivirali |
| CN112940148A (zh) * | 2021-04-06 | 2021-06-11 | 山东众山生物科技有限公司 | 一种透明质酸的纯化方法 |
| IT202100032111A1 (it) | 2021-12-22 | 2023-06-22 | Fidia Farm Spa | Nuovi sostituti biocompatibili dell’umor vitreo |
| CN114805636B (zh) * | 2022-05-26 | 2023-08-04 | 宁夏华吉生物有限公司 | 一种制备透明质酸钠的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4780414A (en) * | 1985-01-18 | 1988-10-25 | Bio-Technology General Corp. | Method of producing high molecular weight sodium hyallronate by fermentation of streptococcus |
| US4784990A (en) * | 1985-01-18 | 1988-11-15 | Bio-Technology General Corporation | High molecular weight sodium hyaluronate |
| JP2587268B2 (ja) * | 1988-04-18 | 1997-03-05 | チッソ株式会社 | 低粘度ヒアルロン酸又はその塩の製造方法 |
| CA2061566C (en) * | 1992-02-20 | 2002-07-09 | Rudolf E. Falk | Treatment of disease employing hyaluronic acid and nsaids |
| IT1247175B (it) * | 1991-04-19 | 1994-12-12 | Fidia Spa | Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. |
| IT1263393B (it) * | 1993-07-30 | 1996-08-05 | Fidia Advanced Biopolymers Srl | Processo per la preparazione e purificazione di acido ialuronico ad alto peso molecolare |
| US6660853B2 (en) * | 2000-12-15 | 2003-12-09 | Al Prescott | Method for purifying high molecular weight hyaluronic acid |
| CA2491054A1 (en) * | 2002-07-03 | 2004-01-15 | Pericor Science, Inc. | Compositions of hyaluronic acid and methods of use |
| AU2003252566A1 (en) * | 2002-08-19 | 2004-03-03 | Kolon Ind. Inc. | Microorganism producing hyaluronic acid and purification method of hyaluronic acid |
| FR2861734B1 (fr) * | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| CN1259345C (zh) * | 2004-08-10 | 2006-06-14 | 江南大学 | 一种从透明质酸发酵液中制备透明质酸钠的方法 |
| KR20120077726A (ko) * | 2010-12-31 | 2012-07-10 | 코오롱생명과학 주식회사 | 히알루론산 및 그 염의 정제방법 |
| ITMI20121184A1 (it) * | 2012-07-05 | 2014-01-06 | Altergon Italia Srl | Processo per la produzione industriale di ialuronato di sodio (hana) altamente purificato a peso molecolare controllato |
| KR101447975B1 (ko) * | 2013-03-25 | 2014-10-13 | 한국식품연구원 | 초음파를 이용한 히알루론산 추출 방법 |
| CN103304684B (zh) * | 2013-06-28 | 2015-07-15 | 四川柯森油田化学有限公司 | 一种提取纯化透明质酸的生产方法 |
-
2016
- 2016-07-28 IT IT102016000079633A patent/IT201600079633A1/it unknown
-
2017
- 2017-07-27 EP EP17755571.1A patent/EP3491027B1/en active Active
- 2017-07-27 PT PT177555711T patent/PT3491027T/pt unknown
- 2017-07-27 US US16/313,409 patent/US10849925B2/en active Active
- 2017-07-27 EA EA201990091A patent/EA039615B1/ru unknown
- 2017-07-27 KR KR1020197002718A patent/KR102391110B1/ko active IP Right Grant
- 2017-07-27 AU AU2017304290A patent/AU2017304290B2/en active Active
- 2017-07-27 HU HUE17755571A patent/HUE050414T2/hu unknown
- 2017-07-27 WO PCT/IB2017/054577 patent/WO2018020458A1/en active Search and Examination
- 2017-07-27 JP JP2019504949A patent/JP6980974B2/ja active Active
- 2017-07-27 PL PL17755571T patent/PL3491027T3/pl unknown
- 2017-07-27 CN CN201780045559.8A patent/CN109563178B/zh active Active
- 2017-07-27 CA CA3030243A patent/CA3030243A1/en active Pending
- 2017-07-27 ES ES17755571T patent/ES2811101T3/es active Active
-
2020
- 2020-10-30 US US17/085,512 patent/US11395833B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6980974B2 (ja) | 2021-12-15 |
| US11395833B2 (en) | 2022-07-26 |
| AU2017304290A1 (en) | 2019-01-24 |
| KR102391110B1 (ko) | 2022-04-26 |
| CN109563178B (zh) | 2021-12-28 |
| PL3491027T3 (pl) | 2020-11-16 |
| US20190224232A1 (en) | 2019-07-25 |
| US10849925B2 (en) | 2020-12-01 |
| HUE050414T2 (hu) | 2020-12-28 |
| EP3491027B1 (en) | 2020-07-01 |
| IT201600079633A1 (it) | 2018-01-28 |
| CA3030243A1 (en) | 2018-02-01 |
| EA039615B1 (ru) | 2022-02-17 |
| AU2017304290B2 (en) | 2020-10-29 |
| US20210046103A1 (en) | 2021-02-18 |
| WO2018020458A1 (en) | 2018-02-01 |
| EP3491027A1 (en) | 2019-06-05 |
| KR20190039099A (ko) | 2019-04-10 |
| CN109563178A (zh) | 2019-04-02 |
| EA201990091A1 (ru) | 2019-05-31 |
| JP2019528055A (ja) | 2019-10-10 |
| ES2811101T3 (es) | 2021-03-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE050414T2 (hu) | Eljárás hialuronsav nátriumsója elõállítására és tisztítására | |
| ZA201706944B (en) | Process for the purification of water | |
| PT3655138T (pt) | Processo para a purificação de ácido hialurónico | |
| HK1254055A1 (zh) | 製備奧貝膽酸及其衍生物的方法 | |
| GB201521581D0 (en) | Methods of purifying nanostructures | |
| HUE050782T2 (hu) | Eljárás Carboprost és trometamin sójának elõállítására | |
| PL3116514T3 (pl) | Koniugaty oligomeru kwasu hialuronowego lub jego soli, sposób ich wytwarzania i ich zastosowanie | |
| HK1250717A1 (zh) | 製備乙酰半乳糖胺酸衍生物的方法 | |
| SG11201710689TA (en) | Process of purifying methionine | |
| HK1220444A1 (zh) | 拉喹莫德鈉晶體和用於製造它們的改進方法 | |
| HUE063127T2 (hu) | Eljárás metilkobalamin tisztítására | |
| PL3271322T3 (pl) | Proces oczyszczania kwasu monochloroacetycznego | |
| PL3328523T3 (pl) | Sposób odzyskiwania siarczanu sodu | |
| ZA201801991B (en) | Process for the preparation of monochloroacetic acid | |
| EP3366641A4 (en) | METHOD FOR PRODUCING A CLEANED AQUEOUS SOLUTION OF SILICA | |
| ZA201704637B (en) | Process in water for the preparation of butyric esters of hyaluronic acid sodium salt | |
| PT3302409T (pt) | Processo e composição para estimular a síntese do ácido hialurónico | |
| EP2997009A4 (en) | Process for the preparation of arformoterol or salt thereof | |
| HUE044225T2 (hu) | Eljárás akrilsav tisztítására | |
| ZA201708170B (en) | Process for the preparation of sodium cyanide | |
| EP3377448A4 (en) | Preparation of magnetite from ferrous chloride subsequent to sulphate removal by ion-exchange | |
| HUE056431T2 (hu) | Eljárás misoprostol elõállítására és tisztítására | |
| SG11201801065PA (en) | An improved process for the preparation of tetrofosmin or acid addition salt thereof | |
| HUE053193T2 (hu) | Eljárás megnövelt stabilitású epoprostenol nátrium elõállítására | |
| SI3397630T1 (sl) | Postoek za pripravo natrijevega pantoprazolata seskvihidrata |