PT3438103T - Composto de griseofulvina - Google Patents

Composto de griseofulvina

Info

Publication number
PT3438103T
PT3438103T PT177751609T PT17775160T PT3438103T PT 3438103 T PT3438103 T PT 3438103T PT 177751609 T PT177751609 T PT 177751609T PT 17775160 T PT17775160 T PT 17775160T PT 3438103 T PT3438103 T PT 3438103T
Authority
PT
Portugal
Prior art keywords
griseofulvin
compound
griseofulvin compound
Prior art date
Application number
PT177751609T
Other languages
English (en)
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of PT3438103T publication Critical patent/PT3438103T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41551,2-Diazoles non condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245Oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT177751609T 2016-03-30 2017-03-29 Composto de griseofulvina PT3438103T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2016067076 2016-03-30

Publications (1)

Publication Number Publication Date
PT3438103T true PT3438103T (pt) 2022-03-09

Family

ID=59965779

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177751609T PT3438103T (pt) 2016-03-30 2017-03-29 Composto de griseofulvina

Country Status (23)

Country Link
US (6) US10570109B2 (pt)
EP (2) EP3438103B1 (pt)
JP (1) JP6808715B2 (pt)
KR (1) KR102419232B1 (pt)
CN (1) CN108779089B (pt)
AU (1) AU2017244777B2 (pt)
BR (1) BR112018069712B1 (pt)
CA (1) CA3018316C (pt)
CO (1) CO2018010787A2 (pt)
DK (1) DK3438103T3 (pt)
ES (1) ES2908221T3 (pt)
HU (1) HUE058182T2 (pt)
IL (1) IL262020B (pt)
MX (1) MX2018011721A (pt)
MY (1) MY195881A (pt)
PH (1) PH12018502012A1 (pt)
PL (1) PL3438103T3 (pt)
PT (1) PT3438103T (pt)
RU (1) RU2736208C2 (pt)
SG (1) SG11201808171PA (pt)
TW (1) TWI738751B (pt)
WO (1) WO2017170623A1 (pt)
ZA (1) ZA201807129B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3438103B1 (en) 2016-03-30 2021-12-08 Daiichi Sankyo Company, Limited Griseofulvin compound
TWI811243B (zh) * 2017-09-29 2023-08-11 日商第一三共股份有限公司 灰黃黴素化合物及醫藥用途
CN108329291B (zh) * 2018-01-31 2021-07-09 青岛理工大学 一种离子液体催化的9-蒽酮内酯类化合物的合成方法
CA3168026A1 (en) * 2020-04-02 2021-10-07 Michael Friedrich ACKERMANN Compositions and methods for treating age-related diseases and premature aging disorders
CN113861144B (zh) * 2021-08-04 2022-06-21 南通大学 一种灰黄霉素开环衍生物及其制备方法
CN116199657A (zh) * 2023-02-20 2023-06-02 延安大学 灰黄霉素4位醚化衍生物及其应用
CN117229246B (zh) * 2023-05-23 2024-06-07 湖北天勤生物科技股份有限公司 具有抗炎活性的化合物及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03255081A (ja) * 1990-03-01 1991-11-13 Mect Corp dl―グリセオフルビン、dl―グリセオフルビン誘導体およびそれらの中間体の製造方法
DE4430910A1 (de) 1994-08-31 1996-03-07 Eisele Rolf Dipl Ing Fh Arzneimittel gegen Tinnitus
WO2003092617A2 (en) 2002-05-03 2003-11-13 Combinatorx, Incorporated Combinations for the treatment of inflammatory skin disorders
EP2008652A1 (en) * 2007-06-28 2008-12-31 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering
EP2204367A1 (en) 2008-12-22 2010-07-07 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Griseofulvin analogues for the treatment of cancer by inhibition of centrosomal clustering
WO2010124695A1 (fr) 2009-04-26 2010-11-04 Soumia Goutali Utilisation de la griseofulvine dans l'amelioration des facultes mentales: attention, concentration et memoire
US9416142B2 (en) * 2012-08-01 2016-08-16 Pierre Fabre Medicament Griseofulvin derivatives
CN104860909B (zh) * 2015-04-09 2017-03-08 西北农林科技大学 灰黄霉素衍生物、灰黄霉素及其衍生物的抗菌活性应用
EP3438103B1 (en) 2016-03-30 2021-12-08 Daiichi Sankyo Company, Limited Griseofulvin compound
TWI811243B (zh) 2017-09-29 2023-08-11 日商第一三共股份有限公司 灰黃黴素化合物及醫藥用途

Also Published As

Publication number Publication date
BR112018069712B1 (pt) 2024-01-02
BR112018069712A2 (pt) 2019-02-05
MY195881A (en) 2023-02-27
AU2017244777B2 (en) 2021-04-01
US10570109B2 (en) 2020-02-25
US20240150309A1 (en) 2024-05-09
US12091395B2 (en) 2024-09-17
TW201738222A (zh) 2017-11-01
TWI738751B (zh) 2021-09-11
US10975052B2 (en) 2021-04-13
MX2018011721A (es) 2019-01-10
US10654821B2 (en) 2020-05-19
KR20180131549A (ko) 2018-12-10
RU2736208C2 (ru) 2020-11-12
CN108779089B (zh) 2022-04-29
CA3018316C (en) 2021-02-16
RU2018137851A3 (pt) 2020-04-30
CA3018316A1 (en) 2017-10-05
KR102419232B1 (ko) 2022-07-08
US20200239425A1 (en) 2020-07-30
WO2017170623A1 (ja) 2017-10-05
DK3438103T3 (da) 2022-03-21
US20230136988A1 (en) 2023-05-04
HUE058182T2 (hu) 2022-07-28
US11472784B2 (en) 2022-10-18
ZA201807129B (en) 2024-09-25
AU2017244777A1 (en) 2018-11-08
EP4032883A1 (en) 2022-07-27
RU2018137851A (ru) 2020-04-30
US11834427B2 (en) 2023-12-05
US20200002302A1 (en) 2020-01-02
JPWO2017170623A1 (ja) 2019-02-07
PL3438103T3 (pl) 2022-03-28
US20190092741A1 (en) 2019-03-28
IL262020B (en) 2021-09-30
US20210292292A1 (en) 2021-09-23
JP6808715B2 (ja) 2021-01-06
SG11201808171PA (en) 2018-10-30
IL262020A (en) 2018-10-31
ES2908221T3 (es) 2022-04-28
CN108779089A (zh) 2018-11-09
EP3438103A4 (en) 2019-10-23
CO2018010787A2 (es) 2018-10-22
EP3438103A1 (en) 2019-02-06
PH12018502012A1 (en) 2019-07-15
EP3438103B1 (en) 2021-12-08

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