PT3436198T - Deteção de ácido nucleico baseada em superfícies num dispositivo fluídico de fluxo de convecção - Google Patents

Deteção de ácido nucleico baseada em superfícies num dispositivo fluídico de fluxo de convecção

Info

Publication number
PT3436198T
PT3436198T PT177764537T PT17776453T PT3436198T PT 3436198 T PT3436198 T PT 3436198T PT 177764537 T PT177764537 T PT 177764537T PT 17776453 T PT17776453 T PT 17776453T PT 3436198 T PT3436198 T PT 3436198T
Authority
PT
Portugal
Prior art keywords
nucleic acid
based detection
fluidic device
convection flow
flow fluidic
Prior art date
Application number
PT177764537T
Other languages
English (en)
Original Assignee
Univ Rice William M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rice William M filed Critical Univ Rice William M
Publication of PT3436198T publication Critical patent/PT3436198T/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0663—Stretching or orienting elongated molecules or particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/513—Detection characterised by immobilisation to a surface characterised by the pattern of the arrayed oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/629—Detection means characterised by use of a special device being a microfluidic device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PT177764537T 2016-03-29 2017-03-28 Deteção de ácido nucleico baseada em superfícies num dispositivo fluídico de fluxo de convecção PT3436198T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662314909P 2016-03-29 2016-03-29

Publications (1)

Publication Number Publication Date
PT3436198T true PT3436198T (pt) 2022-07-13

Family

ID=59965134

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177764537T PT3436198T (pt) 2016-03-29 2017-03-28 Deteção de ácido nucleico baseada em superfícies num dispositivo fluídico de fluxo de convecção

Country Status (16)

Country Link
US (1) US20200324292A1 (pt)
EP (2) EP4063014A1 (pt)
JP (3) JP6998319B2 (pt)
KR (2) KR20230004792A (pt)
CN (1) CN109477136A (pt)
AU (2) AU2017241766A1 (pt)
BR (1) BR112018070197A2 (pt)
CA (1) CA3019422A1 (pt)
DK (1) DK3436198T3 (pt)
ES (1) ES2920954T3 (pt)
IL (1) IL261980B2 (pt)
PH (1) PH12018502100A1 (pt)
PT (1) PT3436198T (pt)
RU (1) RU2018137800A (pt)
SG (1) SG11201808493QA (pt)
WO (1) WO2017172760A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3849707A4 (en) * 2018-09-14 2022-06-01 William Marsh Rice University DEVICE AND METHOD FOR MULTIPLEX AMPLIFICATION AND DETECTION OF DNA USING CONVECTION HEATING AND LABEL-FREE MICROARRAY
CN113257351A (zh) * 2020-02-12 2021-08-13 赛纳生物科技(北京)有限公司 一种用于多碱基基因测序的基因文库及其构建方法
CN111879922A (zh) * 2020-07-13 2020-11-03 东南大学 适用于核酸及免疫同步检测集成纸基芯片结构及制造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027880A (en) 1995-08-02 2000-02-22 Affymetrix, Inc. Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
US6300070B1 (en) 1999-06-04 2001-10-09 Mosaic Technologies, Inc. Solid phase methods for amplifying multiple nucleic acids
US6642000B1 (en) 1999-11-12 2003-11-04 University Of Chicago PCR amplification on microarrays of gel immobilized oligonucleotides
JP2003522963A (ja) * 2000-02-18 2003-07-29 アクララ バイオサイエンシーズ， インコーポレイテッド 複数部位反応デバイスおよび方法
US6586233B2 (en) 2001-03-09 2003-07-01 The Regents Of The University Of California Convectively driven PCR thermal-cycling
RU2216547C2 (ru) 2001-10-16 2003-11-20 Институт молекулярной биологии им. В.А. Энгельгардта РАН Способ полимеризационной иммобилизации биологических макромолекул и композиция для его осуществления
KR100647289B1 (ko) * 2004-09-15 2006-11-23 삼성전자주식회사 마랑고니 대류를 이용한 ｐｃｒ 장치 및 이를 이용한ｐｃｒ 방법
EP2458011B1 (en) * 2005-10-03 2013-07-24 Life Technologies Corporation Compositions, methods, and kits for amplifying nucleic acids
US8114636B2 (en) * 2006-02-10 2012-02-14 Life Technologies Corporation Labeling and detection of nucleic acids
US8735103B2 (en) 2006-12-05 2014-05-27 Electronics And Telecommunications Research Institute Natural convection-driven PCR apparatus and method using disposable polymer chip
WO2008097929A2 (en) 2007-02-05 2008-08-14 California Institute Of Technology Engineered toehold reactions and networks
US8043810B2 (en) 2007-05-02 2011-10-25 Eagle Eye Research, Inc. Analyte detection using autocatalytic chain reactions
ES2717940T3 (es) 2007-07-23 2019-06-26 Alere Tech Gmbh Ensayos
EP2235196A4 (en) 2008-01-24 2011-09-28 Medigen Biotechnology Corp METHODS AND APPARATUSES FOR CONVECTIVE POLYMERASE CHAIN REACTION (PCR)
KR20100025328A (ko) * 2008-08-27 2010-03-09 삼성전자주식회사 이중가닥 영역과 말단 단일가닥 영역을 포함하는 이중가닥 핵산 프로브가 고정된 마이크로어레이를 제조하는 방법
CN102971736B (zh) 2010-05-27 2016-01-27 埃默拉尔德治疗有限公司 利用修饰的核酸传播信息的系统和方法
EP3144396B1 (en) 2010-10-27 2020-01-01 President and Fellows of Harvard College Methods of use of toehold hairpin primer
US20140302486A1 (en) 2011-09-02 2014-10-09 President And Fellows Of Harvard College Systems and methods for detecting biomarkers of interest
JP6427753B2 (ja) * 2013-09-11 2018-11-28 国立大学法人大阪大学 熱対流生成用チップ、熱対流生成装置、及び熱対流生成方法
EP3084051B1 (en) 2013-12-16 2020-01-01 William Marsh Rice University Fine-tuned ultraspecific nucleic acid hybridization probes

Also Published As

Publication number Publication date
RU2018137800A (ru) 2020-04-29
KR20230004792A (ko) 2023-01-06
SG11201808493QA (en) 2018-10-30
AU2017241766A1 (en) 2018-10-25
WO2017172760A1 (en) 2017-10-05
EP3436198A1 (en) 2019-02-06
US20200324292A1 (en) 2020-10-15
KR20190021198A (ko) 2019-03-05
PH12018502100A1 (en) 2019-07-29
ES2920954T3 (es) 2022-08-12
JP2022037151A (ja) 2022-03-08
AU2023203972A1 (en) 2023-07-13
CA3019422A1 (en) 2017-10-05
DK3436198T3 (en) 2022-06-27
JP2019509751A (ja) 2019-04-11
EP4063014A1 (en) 2022-09-28
JP2023184748A (ja) 2023-12-28
CN109477136A (zh) 2019-03-15
KR102472071B1 (ko) 2022-11-29
IL261980B1 (en) 2023-04-01
IL261980B2 (en) 2023-08-01
JP6998319B2 (ja) 2022-01-18
RU2018137800A3 (pt) 2020-06-18
EP3436198B1 (en) 2022-05-04
EP3436198A4 (en) 2019-10-30
IL261980A (en) 2018-10-31
BR112018070197A2 (pt) 2019-01-29

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