PT3181691T - Anticorpo anti-fcf23 e composição farmacêutica que o compreende - Google Patents

Anticorpo anti-fcf23 e composição farmacêutica que o compreende

Info

Publication number
PT3181691T
PT3181691T PT171521685T PT17152168T PT3181691T PT 3181691 T PT3181691 T PT 3181691T PT 171521685 T PT171521685 T PT 171521685T PT 17152168 T PT17152168 T PT 17152168T PT 3181691 T PT3181691 T PT 3181691T
Authority
PT
Portugal
Prior art keywords
same
pharmaceutical composition
fgf23 antibody
anti fgf23
antibody
Prior art date
Application number
PT171521685T
Other languages
English (en)
Original Assignee
Kyowa Hakko Kirin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39690189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3181691(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kirin Co Ltd filed Critical Kyowa Hakko Kirin Co Ltd
Publication of PT3181691T publication Critical patent/PT3181691T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
PT171521685T 2007-02-14 2008-02-14 Anticorpo anti-fcf23 e composição farmacêutica que o compreende PT3181691T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007034018 2007-02-14

Publications (1)

Publication Number Publication Date
PT3181691T true PT3181691T (pt) 2020-08-26

Family

ID=39690189

Family Applications (3)

Application Number Title Priority Date Filing Date
PT171521685T PT3181691T (pt) 2007-02-14 2008-02-14 Anticorpo anti-fcf23 e composição farmacêutica que o compreende
PT87117073T PT2128253E (pt) 2007-02-14 2008-02-14 Anticorpo anti-fgf23 e composição farmacêutica que o compreende
PT121709844T PT2502996T (pt) 2007-02-14 2008-02-14 Anticorpo anti-fgf23 e composição farmacêutica que o compreende

Family Applications After (2)

Application Number Title Priority Date Filing Date
PT87117073T PT2128253E (pt) 2007-02-14 2008-02-14 Anticorpo anti-fgf23 e composição farmacêutica que o compreende
PT121709844T PT2502996T (pt) 2007-02-14 2008-02-14 Anticorpo anti-fgf23 e composição farmacêutica que o compreende

Country Status (23)

Country Link
US (4) US7883705B2 (pt)
EP (3) EP2128253B1 (pt)
JP (1) JP4800396B2 (pt)
KR (1) KR101462291B1 (pt)
CN (2) CN101652476B (pt)
AU (1) AU2008215346B2 (pt)
CA (1) CA2677782C (pt)
CY (3) CY1118835T1 (pt)
DK (3) DK2502996T3 (pt)
ES (3) ES2811318T3 (pt)
FR (1) FR18C1032I2 (pt)
HK (2) HK1140228A1 (pt)
HR (2) HRP20170548T1 (pt)
HU (3) HUE031728T2 (pt)
LT (3) LT2502996T (pt)
LU (2) LUC00082I2 (pt)
NL (1) NL300945I2 (pt)
NO (1) NO2018025I1 (pt)
PL (3) PL2502996T3 (pt)
PT (3) PT3181691T (pt)
SI (2) SI3181691T1 (pt)
TW (1) TWI422593B (pt)
WO (1) WO2008099969A1 (pt)

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Publication number Priority date Publication date Assignee Title
DE60142239D1 (de) * 2000-08-11 2010-07-08 Kyowa Hakko Kirin Co Ltd DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE
ATE441666T1 (de) * 2001-12-28 2009-09-15 Kyowa Hakko Kirin Co Ltd Antikírper gegen den fibroblastenwachstumsfaktor 23
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2012050673A1 (en) * 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
WO2012177481A2 (en) 2011-06-24 2012-12-27 University Of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
CN106604743A (zh) 2014-06-09 2017-04-26 奥特吉尼克斯制药公司 用于最佳骨形成的血清磷酸盐的有效和高效控制
WO2018069232A1 (en) 2016-10-10 2018-04-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of having cardiac hypertrophy
WO2018181935A1 (ja) 2017-03-30 2018-10-04 シスメックス株式会社 抗ApoA1抗体
CN113950355A (zh) * 2019-03-29 2022-01-18 阿塔盖有限责任公司 Fgf23的抗体分子和其用途
WO2024034638A1 (ja) * 2022-08-10 2024-02-15 協和キリン株式会社 抗fgf23抗体又は該抗体断片

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GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61178926U (pt) 1985-04-23 1986-11-08
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
FI884924A (fi) 1987-10-28 1989-04-29 Oncogen Humanimmuglobulin som producerats med hybrid-dna-teknik.
JP2958019B2 (ja) 1988-05-06 1999-10-06 住友製薬株式会社 ポリエチレングリコール誘導体、修飾ペプチドおよびその製造方法
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
WO1999060017A2 (en) 1998-05-18 1999-11-25 University College London Human tumour-derived polypeptide hormone phosphatonin
TWI255853B (en) 1998-08-21 2006-06-01 Kirin Brewery Method for modifying chromosomes
WO2000060085A1 (en) 1999-04-02 2000-10-12 Millennium Pharmaceuticals, Inc. Fibroblast growth factor-20
US6596849B1 (en) * 1999-05-28 2003-07-22 Academia Sinica Monoclonal-antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules
CA2383254A1 (en) 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2490909A1 (en) 1999-12-01 2001-06-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2382165A1 (en) 1999-12-08 2001-06-14 Genset S.A. Full-length human cdnas encoding potentially secreted proteins
EP1246843A1 (en) 2000-01-05 2002-10-09 ZymoGenetics, Inc. Novel fgf homolog zfgf12
US20030149238A1 (en) 2000-02-14 2003-08-07 Pankaj Agarwal Novel compounds
MXPA02007619A (es) 2000-02-15 2002-12-13 Amgen Inc Moleculas de factor 23 de crecimiento de fibroblastos y su uso.
US20060160181A1 (en) * 2000-02-15 2006-07-20 Amgen Inc. Fibroblast Growth Factor-23 molecules and uses thereof
WO2001066595A2 (en) 2000-03-08 2001-09-13 Chiron Corporation Human fgf-23 gene and gene expression products
WO2001066596A2 (en) 2000-03-08 2001-09-13 Chiron Corporation Human fgf-23 gene and gene expression products
CA2418215A1 (en) 2000-07-19 2002-01-31 Advanced Research & Technology Institute Novel fibroblast growth factor (fgf23) and methods for use
DE60142239D1 (de) 2000-08-11 2010-07-08 Kyowa Hakko Kirin Co Ltd DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE
PT1354034E (pt) 2000-11-30 2008-02-28 Medarex Inc Roedores transgénicos transcromossómicos para produção de anticorpos humanos
WO2002076467A1 (en) 2001-03-22 2002-10-03 Genzyme Corporation Compositions and methods to regulate bone and mineral metabolism
EP1381683A2 (en) * 2001-04-26 2004-01-21 Geneprot, Inc. Human fibroblast growth factor-related compositions
EP2011802A3 (en) * 2001-04-27 2009-04-15 Kyowa Hakko Kirin Co., Ltd. Anti-CD40 monoclonal antibody
ATE441666T1 (de) * 2001-12-28 2009-09-15 Kyowa Hakko Kirin Co Ltd Antikírper gegen den fibroblastenwachstumsfaktor 23
US7094551B2 (en) * 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
US20070036734A1 (en) * 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
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US20100062984A1 (en) * 2007-01-25 2010-03-11 Rajiv Kumar Fgf-23 polypeptides
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
EP2128253B1 (en) 2014-12-03
NL300945I2 (en) 2020-05-13
HUE050517T2 (hu) 2020-12-28
CY1123240T1 (el) 2021-10-29
EP2502996A2 (en) 2012-09-26
CN101652476A (zh) 2010-02-17
HK1140228A1 (en) 2010-10-08
HRP20170548T1 (hr) 2017-08-25
EP2502996A3 (en) 2013-04-10
SI2502996T1 (sl) 2017-08-31
EP2502996B1 (en) 2017-03-29
PL3181691T3 (pl) 2020-11-02
LTPA2018508I1 (lt) 2018-09-10
LUC00082I2 (pt) 2018-10-01
JP4800396B2 (ja) 2011-10-26
KR20090114452A (ko) 2009-11-03
LTC2502996I2 (lt) 2019-05-10
WO2008099969A1 (ja) 2008-08-21
SI3181691T1 (sl) 2020-09-30
EP3181691A1 (en) 2017-06-21
DK2502996T3 (en) 2017-05-08
JPWO2008099969A1 (ja) 2010-05-27
PT2502996T (pt) 2017-05-10
US7883705B2 (en) 2011-02-08
CN102702355B (zh) 2014-09-24
HK1172917A1 (en) 2013-05-03
AU2008215346B2 (en) 2013-01-10
PL2128253T3 (pl) 2015-04-30
EP2128253A1 (en) 2009-12-02
CN101652476B (zh) 2012-07-04
US20110182913A1 (en) 2011-07-28
CA2677782A1 (en) 2008-08-21
NO2018025I1 (no) 2018-08-09
EP3181691B1 (en) 2020-07-15
FR18C1032I2 (fr) 2019-08-09
CY1118835T1 (el) 2018-01-10
FR18C1032I1 (pt) 2018-08-31
US20090148461A1 (en) 2009-06-11
DK2128253T3 (en) 2015-01-05
CA2677782C (en) 2016-07-26
LT2502996T (lt) 2017-06-26
ES2530670T3 (es) 2015-03-04
US9290569B2 (en) 2016-03-22
US20190106485A1 (en) 2019-04-11
ES2811318T3 (es) 2021-03-11
AU2008215346A1 (en) 2008-08-21
CY2018021I1 (el) 2019-07-10
EP2128253A4 (en) 2010-03-10
US20160159895A1 (en) 2016-06-09
PL2502996T3 (pl) 2017-07-31
KR101462291B1 (ko) 2014-11-14
PT2128253E (pt) 2015-02-04
HUS1800034I1 (hu) 2018-09-28
HUE031728T2 (en) 2017-07-28
NL300945I1 (en) 2018-08-15
CY2018021I2 (el) 2019-07-10
US10202446B2 (en) 2019-02-12
DK3181691T3 (da) 2020-08-17
LUC00081I2 (pt) 2018-10-01
HRP20201266T1 (hr) 2021-02-05
TW200902549A (en) 2009-01-16
ES2625823T3 (es) 2017-07-20
TWI422593B (zh) 2014-01-11
CN102702355A (zh) 2012-10-03
LT3181691T (lt) 2020-08-25

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