SI2502996T1 - Anti-fgf23 protitelo in farmacevtski sestavek, ki ga vsebuje - Google Patents

Anti-fgf23 protitelo in farmacevtski sestavek, ki ga vsebuje

Info

Publication number
SI2502996T1
SI2502996T1 SI200831797T SI200831797T SI2502996T1 SI 2502996 T1 SI2502996 T1 SI 2502996T1 SI 200831797 T SI200831797 T SI 200831797T SI 200831797 T SI200831797 T SI 200831797T SI 2502996 T1 SI2502996 T1 SI 2502996T1
Authority
SI
Slovenia
Prior art keywords
same
pharmaceutical composition
fgf23 antibody
fgf23
antibody
Prior art date
Application number
SI200831797T
Other languages
English (en)
Inventor
Yuji Yamazaki
Itaru Urakawa
Hitoshi Yoshida
Yukiko Aono
Takeyoshi Yamashita
Takashi Shimada
Hisashi Hasegawa
Original Assignee
Kyowa Hakko Kirin Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39690189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2502996(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kirin Co., Ltd. filed Critical Kyowa Hakko Kirin Co., Ltd.
Publication of SI2502996T1 publication Critical patent/SI2502996T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
SI200831797T 2007-02-14 2008-02-14 Anti-fgf23 protitelo in farmacevtski sestavek, ki ga vsebuje SI2502996T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007034018 2007-02-14
EP12170984.4A EP2502996B1 (en) 2007-02-14 2008-02-14 Anti-FGF23 antibody and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
SI2502996T1 true SI2502996T1 (sl) 2017-08-31

Family

ID=39690189

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200832131T SI3181691T1 (sl) 2007-02-14 2008-02-14 Anti FGF23 protitelo in farmacevtski sestavek, ki ga vsebuje
SI200831797T SI2502996T1 (sl) 2007-02-14 2008-02-14 Anti-fgf23 protitelo in farmacevtski sestavek, ki ga vsebuje

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200832131T SI3181691T1 (sl) 2007-02-14 2008-02-14 Anti FGF23 protitelo in farmacevtski sestavek, ki ga vsebuje

Country Status (23)

Country Link
US (4) US7883705B2 (sl)
EP (3) EP2502996B1 (sl)
JP (1) JP4800396B2 (sl)
KR (1) KR101462291B1 (sl)
CN (2) CN102702355B (sl)
AU (1) AU2008215346B2 (sl)
CA (1) CA2677782C (sl)
CY (3) CY1118835T1 (sl)
DK (3) DK2128253T3 (sl)
ES (3) ES2625823T3 (sl)
FR (1) FR18C1032I2 (sl)
HK (2) HK1140228A1 (sl)
HR (2) HRP20170548T1 (sl)
HU (3) HUE031728T2 (sl)
LT (3) LT3181691T (sl)
LU (2) LUC00082I2 (sl)
NL (1) NL300945I2 (sl)
NO (1) NO2018025I1 (sl)
PL (3) PL3181691T3 (sl)
PT (3) PT3181691T (sl)
SI (2) SI3181691T1 (sl)
TW (1) TWI422593B (sl)
WO (1) WO2008099969A1 (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4799801B2 (ja) * 2000-08-11 2011-10-26 協和発酵キリン株式会社 リン酸代謝、カルシウム代謝、石灰化及びビタミンd代謝を調節するポリペプチド並びにそれをコードするdna
CA2471656C (en) * 2001-12-28 2012-07-31 Kirin Beer Kabushiki Kaisha Antibody against fibroblast growth factor-23
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2012050673A1 (en) 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Methods for the treatment of x-linked hypophosphatemia and related disorders
US20140294820A1 (en) 2011-06-24 2014-10-02 University Of Miami Fibroblast growth factor receptor inhibition for the treatment of disease
SI3151859T1 (sl) * 2014-06-09 2021-06-30 Ultragenyx Pharmaceutical Inc. Uspešen in učinkovit nadzor serumskega fosfata za optimalno tvorbo kosti
WO2018069232A1 (en) 2016-10-10 2018-04-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of having cardiac hypertrophy
WO2018181935A1 (ja) 2017-03-30 2018-10-04 シスメックス株式会社 抗ApoA1抗体
AU2020253833A1 (en) * 2019-03-29 2021-10-28 Atarga, Llc Anti FGF23 antibody
WO2024034638A1 (ja) * 2022-08-10 2024-02-15 協和キリン株式会社 抗fgf23抗体又は該抗体断片

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JPS61178926U (sl) 1985-04-23 1986-11-08
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
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JP2958019B2 (ja) 1988-05-06 1999-10-06 住友製薬株式会社 ポリエチレングリコール誘導体、修飾ペプチドおよびその製造方法
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
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TWI255853B (en) 1998-08-21 2006-06-01 Kirin Brewery Method for modifying chromosomes
WO2000060085A1 (en) 1999-04-02 2000-10-12 Millennium Pharmaceuticals, Inc. Fibroblast growth factor-20
US6596849B1 (en) * 1999-05-28 2003-07-22 Academia Sinica Monoclonal-antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules
AU3774300A (en) 1999-06-02 2000-12-18 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2492070A1 (en) 1999-12-01 2001-06-07 Kevin P. Baker Lung tumor marker pro4329 polypeptides and nucleic acids encoding the same
JP2003516150A (ja) 1999-12-08 2003-05-13 ジェンセット 潜在性分泌タンパク質をコードする全長ヒトcDNA
WO2001049740A1 (en) 2000-01-05 2001-07-12 Zymogenetics, Inc. Novel fgf homolog zfgf12
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JP4799801B2 (ja) * 2000-08-11 2011-10-26 協和発酵キリン株式会社 リン酸代謝、カルシウム代謝、石灰化及びビタミンd代謝を調節するポリペプチド並びにそれをコードするdna
ES2405944T3 (es) 2000-11-30 2013-06-04 Medarex, Inc. Ácidos nucleicos que codifican las secuencias de inmunoglobulina humana reorganizadas a partir de ratones transcromoscómicos transgénicos zadas
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JP2004527253A (ja) * 2001-04-26 2004-09-09 ジーンプロット・インコーポレイテッド 線維芽細胞成長因子−23分子およびその使用
EP2009027B1 (en) * 2001-04-27 2014-05-21 Kyowa Hakko Kirin Co., Ltd. Anti-CD40 monoclonal antibody
CA2471656C (en) 2001-12-28 2012-07-31 Kirin Beer Kabushiki Kaisha Antibody against fibroblast growth factor-23
US7094551B2 (en) * 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
US20070036734A1 (en) * 2003-03-17 2007-02-15 Kirin Beer Kabushiki Kaisha Therapeutic agent for periodontal disease
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US20100062984A1 (en) * 2007-01-25 2010-03-11 Rajiv Kumar Fgf-23 polypeptides
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
KR20090114452A (ko) 2009-11-03
DK2502996T3 (en) 2017-05-08
LT2502996T (lt) 2017-06-26
LTC2502996I2 (lt) 2019-05-10
PL2128253T3 (pl) 2015-04-30
NL300945I2 (en) 2020-05-13
CN102702355B (zh) 2014-09-24
CN102702355A (zh) 2012-10-03
AU2008215346A1 (en) 2008-08-21
US20090148461A1 (en) 2009-06-11
LUC00081I2 (sl) 2018-10-01
DK2128253T3 (en) 2015-01-05
SI3181691T1 (sl) 2020-09-30
ES2530670T3 (es) 2015-03-04
HK1140228A1 (en) 2010-10-08
US20190106485A1 (en) 2019-04-11
AU2008215346B2 (en) 2013-01-10
CY2018021I1 (el) 2019-07-10
DK3181691T3 (da) 2020-08-17
US20110182913A1 (en) 2011-07-28
EP2502996A2 (en) 2012-09-26
CN101652476B (zh) 2012-07-04
LUC00082I2 (sl) 2018-10-01
US20160159895A1 (en) 2016-06-09
EP3181691A1 (en) 2017-06-21
PL3181691T3 (pl) 2020-11-02
EP2502996A3 (en) 2013-04-10
KR101462291B1 (ko) 2014-11-14
US7883705B2 (en) 2011-02-08
HRP20201266T1 (hr) 2021-02-05
WO2008099969A1 (ja) 2008-08-21
JP4800396B2 (ja) 2011-10-26
HUS1800034I1 (hu) 2018-09-28
HUE031728T2 (en) 2017-07-28
TWI422593B (zh) 2014-01-11
CY1118835T1 (el) 2018-01-10
CY2018021I2 (el) 2019-07-10
PT2128253E (pt) 2015-02-04
HUE050517T2 (hu) 2020-12-28
HRP20170548T1 (hr) 2017-08-25
HK1172917A1 (en) 2013-05-03
EP2128253A4 (en) 2010-03-10
JPWO2008099969A1 (ja) 2010-05-27
TW200902549A (en) 2009-01-16
EP2502996B1 (en) 2017-03-29
CY1123240T1 (el) 2021-10-29
CA2677782A1 (en) 2008-08-21
NL300945I1 (en) 2018-08-15
FR18C1032I1 (sl) 2018-08-31
US10202446B2 (en) 2019-02-12
PT2502996T (pt) 2017-05-10
US9290569B2 (en) 2016-03-22
LT3181691T (lt) 2020-08-25
EP2128253A1 (en) 2009-12-02
EP3181691B1 (en) 2020-07-15
NO2018025I1 (no) 2018-08-09
FR18C1032I2 (fr) 2019-08-09
CA2677782C (en) 2016-07-26
LTPA2018508I1 (lt) 2018-09-10
PL2502996T3 (pl) 2017-07-31
PT3181691T (pt) 2020-08-26
CN101652476A (zh) 2010-02-17
ES2811318T3 (es) 2021-03-11
EP2128253B1 (en) 2014-12-03
ES2625823T3 (es) 2017-07-20

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