FR18C1032I2 - Anticorps anti-fgf23 et composition pharmaceutique le comprenant - Google Patents

Anticorps anti-fgf23 et composition pharmaceutique le comprenant

Info

Publication number
FR18C1032I2
FR18C1032I2 FR18C1032C FR18C1032C FR18C1032I2 FR 18C1032 I2 FR18C1032 I2 FR 18C1032I2 FR 18C1032 C FR18C1032 C FR 18C1032C FR 18C1032 C FR18C1032 C FR 18C1032C FR 18C1032 I2 FR18C1032 I2 FR 18C1032I2
Authority
FR
France
Prior art keywords
pharmaceutical composition
fgf23 antibodies
fgf23
antibodies
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR18C1032C
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Co Ltd
Original Assignee
Kyowa Hakko Kirin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39690189&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR18C1032(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kirin Co Ltd filed Critical Kyowa Hakko Kirin Co Ltd
Publication of FR18C1032I1 publication Critical patent/FR18C1032I1/fr
Application granted granted Critical
Publication of FR18C1032I2 publication Critical patent/FR18C1032I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
FR18C1032C 2007-02-14 2018-07-27 Anticorps anti-fgf23 et composition pharmaceutique le comprenant Active FR18C1032I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007034018 2007-02-14
PCT/JP2008/052918 WO2008099969A1 (fr) 2007-02-14 2008-02-14 Anticorps anti-fgf23 et composition pharmaceutique le comprenant

Publications (2)

Publication Number Publication Date
FR18C1032I1 FR18C1032I1 (fr) 2018-08-31
FR18C1032I2 true FR18C1032I2 (fr) 2019-08-09

Family

ID=39690189

Family Applications (1)

Application Number Title Priority Date Filing Date
FR18C1032C Active FR18C1032I2 (fr) 2007-02-14 2018-07-27 Anticorps anti-fgf23 et composition pharmaceutique le comprenant

Country Status (23)

Country Link
US (4) US7883705B2 (fr)
EP (3) EP2128253B1 (fr)
JP (1) JP4800396B2 (fr)
KR (1) KR101462291B1 (fr)
CN (2) CN101652476B (fr)
AU (1) AU2008215346B2 (fr)
CA (1) CA2677782C (fr)
CY (3) CY1118835T1 (fr)
DK (3) DK2502996T3 (fr)
ES (3) ES2811318T3 (fr)
FR (1) FR18C1032I2 (fr)
HK (2) HK1140228A1 (fr)
HR (2) HRP20170548T1 (fr)
HU (3) HUE031728T2 (fr)
LT (3) LT2502996T (fr)
LU (2) LUC00082I2 (fr)
NL (1) NL300945I2 (fr)
NO (1) NO2018025I1 (fr)
PL (3) PL2502996T3 (fr)
PT (3) PT3181691T (fr)
SI (2) SI3181691T1 (fr)
TW (1) TWI422593B (fr)
WO (1) WO2008099969A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60142239D1 (de) * 2000-08-11 2010-07-08 Kyowa Hakko Kirin Co Ltd DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE
ATE441666T1 (de) * 2001-12-28 2009-09-15 Kyowa Hakko Kirin Co Ltd Antikírper gegen den fibroblastenwachstumsfaktor 23
US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same
WO2012050673A1 (fr) * 2010-10-14 2012-04-19 Wisconsin Alumni Research Foundation Méthodes de traitement de l'hypophosphatémie liée à l'x et de troubles associés
WO2012177481A2 (fr) 2011-06-24 2012-12-27 University Of Miami Inhibition du récepteur du facteur de croissance des fibroblastes pour le traitement de maladies
CN106604743A (zh) 2014-06-09 2017-04-26 奥特吉尼克斯制药公司 用于最佳骨形成的血清磷酸盐的有效和高效控制
WO2018069232A1 (fr) 2016-10-10 2018-04-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédés de prédiction du risque de présenter une hypertrophie cardiaque
WO2018181935A1 (fr) 2017-03-30 2018-10-04 シスメックス株式会社 Anticorps anti-apoa1
CN113950355A (zh) * 2019-03-29 2022-01-18 阿塔盖有限责任公司 Fgf23的抗体分子和其用途
WO2024034638A1 (fr) * 2022-08-10 2024-02-15 協和キリン株式会社 Anticorps anti-fgf23 et fragment dudit anticorps

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JPS5623587A (en) 1979-08-03 1981-03-05 Mitsuwa Seiki Co Ltd Vane type compressor
WO1985003934A1 (fr) 1984-03-06 1985-09-12 Takeda Chemical Industries, Ltd. Proteine modifiee chimiquement et son procede de preparation
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61178926U (fr) 1985-04-23 1986-11-08
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
FI884924A (fi) 1987-10-28 1989-04-29 Oncogen Humanimmuglobulin som producerats med hybrid-dna-teknik.
JP2958019B2 (ja) 1988-05-06 1999-10-06 住友製薬株式会社 ポリエチレングリコール誘導体、修飾ペプチドおよびその製造方法
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5958879A (en) * 1989-10-12 1999-09-28 Ohio University/Edison Biotechnology Institute Growth hormone receptor antagonists and methods of reducing growth hormone activity in a mammal
US5859205A (en) * 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US6001358A (en) 1995-11-07 1999-12-14 Idec Pharmaceuticals Corporation Humanized antibodies to human gp39, compositions containing thereof
WO1999060017A2 (fr) 1998-05-18 1999-11-25 University College London Nouveau polypeptide du type phosphatonine hormonale
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WO2000060085A1 (fr) 1999-04-02 2000-10-12 Millennium Pharmaceuticals, Inc. Facteur de croissance 20 des fibroblastes
US6596849B1 (en) * 1999-05-28 2003-07-22 Academia Sinica Monoclonal-antibody for analysis and clearance of polyethylene glycol and polyethylene glycol-modified molecules
CA2383254A1 (fr) 1999-06-02 2000-12-07 Genentech, Inc. Polypeptides transmembranaires secretes et acides nucleiques codants pour ceux-ci
CA2490909A1 (fr) 1999-12-01 2001-06-07 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
CA2382165A1 (fr) 1999-12-08 2001-06-14 Genset S.A. Adnc humains pleine longueur codant pour des proteines potentiellement secretees
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WO2001066596A2 (fr) 2000-03-08 2001-09-13 Chiron Corporation Gene humain fgf-23 et produits d'expression genique
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DE60142239D1 (de) 2000-08-11 2010-07-08 Kyowa Hakko Kirin Co Ltd DEN PHOSPHORSÄURE-METABOLISMUS, DEN KALZIUM-METABOLISMUS, VERKALKUNG UND DEN VITAMIN D-METABOLISMUS KONTROLLIERENDE POLYPEPTIDE SOWIE FüR DIESE KODIERENDE DNA-MOLEKÜLE
PT1354034E (pt) 2000-11-30 2008-02-28 Medarex Inc Roedores transgénicos transcromossómicos para produção de anticorpos humanos
WO2002076467A1 (fr) 2001-03-22 2002-10-03 Genzyme Corporation Compositions et procedes de regulation du metabolisme osseux et mineral
EP1381683A2 (fr) * 2001-04-26 2004-01-21 Geneprot, Inc. Compositions associees au facteur de croissance de fibroblastes humain
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ATE441666T1 (de) * 2001-12-28 2009-09-15 Kyowa Hakko Kirin Co Ltd Antikírper gegen den fibroblastenwachstumsfaktor 23
US7094551B2 (en) * 2002-09-17 2006-08-22 Zahradnik Richard J Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23
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US7883705B2 (en) * 2007-02-14 2011-02-08 Kyowa Hakko Kirin Co., Ltd. Anti FGF23 antibody and a pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
EP2128253B1 (fr) 2014-12-03
NL300945I2 (en) 2020-05-13
HUE050517T2 (hu) 2020-12-28
CY1123240T1 (el) 2021-10-29
EP2502996A2 (fr) 2012-09-26
CN101652476A (zh) 2010-02-17
HK1140228A1 (en) 2010-10-08
HRP20170548T1 (hr) 2017-08-25
EP2502996A3 (fr) 2013-04-10
SI2502996T1 (sl) 2017-08-31
EP2502996B1 (fr) 2017-03-29
PL3181691T3 (pl) 2020-11-02
LTPA2018508I1 (lt) 2018-09-10
LUC00082I2 (fr) 2018-10-01
JP4800396B2 (ja) 2011-10-26
KR20090114452A (ko) 2009-11-03
LTC2502996I2 (lt) 2019-05-10
WO2008099969A1 (fr) 2008-08-21
SI3181691T1 (sl) 2020-09-30
EP3181691A1 (fr) 2017-06-21
DK2502996T3 (en) 2017-05-08
JPWO2008099969A1 (ja) 2010-05-27
PT2502996T (pt) 2017-05-10
US7883705B2 (en) 2011-02-08
CN102702355B (zh) 2014-09-24
HK1172917A1 (en) 2013-05-03
AU2008215346B2 (en) 2013-01-10
PL2128253T3 (pl) 2015-04-30
EP2128253A1 (fr) 2009-12-02
CN101652476B (zh) 2012-07-04
US20110182913A1 (en) 2011-07-28
CA2677782A1 (fr) 2008-08-21
NO2018025I1 (no) 2018-08-09
EP3181691B1 (fr) 2020-07-15
CY1118835T1 (el) 2018-01-10
FR18C1032I1 (fr) 2018-08-31
US20090148461A1 (en) 2009-06-11
DK2128253T3 (en) 2015-01-05
CA2677782C (fr) 2016-07-26
LT2502996T (lt) 2017-06-26
ES2530670T3 (es) 2015-03-04
US9290569B2 (en) 2016-03-22
US20190106485A1 (en) 2019-04-11
ES2811318T3 (es) 2021-03-11
PT3181691T (pt) 2020-08-26
AU2008215346A1 (en) 2008-08-21
CY2018021I1 (el) 2019-07-10
EP2128253A4 (fr) 2010-03-10
US20160159895A1 (en) 2016-06-09
PL2502996T3 (pl) 2017-07-31
KR101462291B1 (ko) 2014-11-14
PT2128253E (pt) 2015-02-04
HUS1800034I1 (hu) 2018-09-28
HUE031728T2 (en) 2017-07-28
NL300945I1 (en) 2018-08-15
CY2018021I2 (el) 2019-07-10
US10202446B2 (en) 2019-02-12
DK3181691T3 (da) 2020-08-17
LUC00081I2 (fr) 2018-10-01
HRP20201266T1 (hr) 2021-02-05
TW200902549A (en) 2009-01-16
ES2625823T3 (es) 2017-07-20
TWI422593B (zh) 2014-01-11
CN102702355A (zh) 2012-10-03
LT3181691T (lt) 2020-08-25

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